Abstract
Current research indicates a strong familial risk for the development of attention deficit hyperactivity disorder (ADHD) among offspring of parents with ADHD that results from genetic risk factors (see Chapter 3). The rate of ADHD among first-degree relatives is reported to be in the region of 10–20 % for the siblings and parents of a child with ADHD. However, the genetic transmission is complex and not sufficiently understood to enable clinicians to offer any specific prenatal advice to mothers with ADHD. Though genes play a part in the development of the disorder, it is clear that social, educational, and psychological factors also play an important role in developmental course and long-term outcome, and therefore genetic loading should not be seen as the only determining factor. General advice should therefore be given to parents with ADHD on the risk to their offspring of developing ADHD, and strategies considered to reduce any potentially negative effects of parental ADHD on their developing child.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Chen W, Zhou K, Sham P, et al. DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkage. Am J Med Genet B Neuropsychiatr Genet. 2008;147B:1450–60.
Faraone SV, Biederman J, Monuteaux MC. Toward guidelines for pedigree selection in genetic studies of attention deficit hyperactivity disorder. Genet Epidemiol. 2000;18:1–16.
Humphreys C, Garcia-Bournissen F, Ito S, et al. Exposure to attention deficit hyperactivity disorder medications during pregnancy. Can Fam Phys. 2007;53:1153–5.
Cole JA, Modell JG, Haight BR, Cosmatos IS, Stoler JM, Walker AM. Bupropion in pregnancy and the prevalence of congenital malformations. Pharmacoepidemiol Drug Saf. 2007;16:474–84.
Linnet KM, Dalsgaard S, Obel C, et al. Maternal lifestyle factors in pregnancy risk of attention deficit hyperactivity disorder and associated behaviors: review of the current evidence. Am J Psychiatry. 2003;160:1028–40.
Rodriguez A, Bohlin G. Are maternal smoking and stress during pregnancy related to ADHD symptoms in children? J Child Psychol Psychiatry. 2005;46:246–54.
de Zeeuw P, Zwart F, Schrama R, van Engeland H, Durston S. Prenatal exposure to cigarette smoke or alcohol and cerebellum volume in attention-deficit/hyperactivity disorder and typical development. Transl Psychiatry. 2012;2:e84.
Grizenko N, Shayan YR, Polotskaia A, et al. Relation of maternal stress during pregnancy to symptom severity and response to treatment in children with ADHD. J Psychiatr Neurosci. 2008;33:10–6.
Thapar A, Rice F, Hay D, et al. Prenatal smoking might not cause attention-deficit/hyperactivity disorder: evidence from a novel design. Biol Psychiatry. 2009;66:722–7.
Aarnoudse-Moens CS, Weisglas-Kuperus N, van Goudoever JB, et al. Meta-analysis of neurobehavioral outcomes in very preterm and/or very low birth weight children. Pediatrics. 2009;124:717–28.
Dahl LB, Kaaresen P, Tunby J, et al. Emotional, behavioral, social, and academic outcomes in adolescents born with very low birth weight. Pediatrics. 2006;118:e449–59.
Shum D, Neulinger K, O’Callaghan M, et al. Attentional problems in children born very preterm or with extremely low birth weight at 7–9 years. Arch Clin Neuropsychol. 2008;23:103–12.
Milberger S, Biederman J, Faraone SV, et al. Pregnancy, delivery and infancy complications and attention deficit hyperactivity disorder: issues of gene-environment interaction. Biol Psychiatry. 1997;41:65–75.
Hackett P, Kristensen JH, Hale TW, Paterson R, Ilett KF. Methylphenidate and breast-feeding. Pharmacother. 2006;40:1890–1.
European Medicines Agency (EMA). Modafinil summary of product characteristics. EMA website. www.ema.europa.eu/docs/en_GB/document_library/Referrals_document/Modafinil_31/WC500099178.pdf. Accessed 24 Aug 2012.
Taddio A, Ito S. Drugs and breastfeeding. In: Koren G, editors. Maternal-fetal toxicology, a clinician’s guide. 3rd ed. New York, US: Dekker M, Inc; 2001. p. 177–233.
Author information
Authors and Affiliations
Consortia
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Healthcare
About this chapter
Cite this chapter
UKAAN. (2013). Attention Deficit Hyperactivity Disorder During Pregnancy. In: Handbook for Attention Deficit Hyperactivity Disorder in Adults. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-908517-79-1_9
Download citation
DOI: https://doi.org/10.1007/978-1-908517-79-1_9
Published:
Publisher Name: Springer Healthcare, Tarporley
Print ISBN: 978-1-908517-50-0
Online ISBN: 978-1-908517-79-1
eBook Packages: MedicineMedicine (R0)