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Perinatal and Postnatal Determinants of Brain Development: Recent Studies and Methodological Advances

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Book cover Prenatal and Postnatal Determinants of Development

Part of the book series: Neuromethods ((NM,volume 109))

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Abstract

Perinatal diet is an important factor in programming brain development and susceptibility to obesity. There are currently several elegant and simple prenatal and postnatal animal models in use to mimic the effects of early life overfeeding and to study its impact on brain and metabolic development. In this chapter we will discuss the background to some of these models, with a specific focus on manipulating rodent litter sizes to alter the early life nutritional environment.

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Acknowledgements

This work was supported by a Discovery Project Grant from the Australian Research Council (ARC) to SJS (DP130100508). SJS is an ARC Future Fellow (FT110100084) and an RMIT University VC Senior Research Fellow.

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Authors and Affiliations

  1. School of Health Sciences, Health Innovations Research Institute (HIRi), RMIT University, Bundoora Campus, Melbourne, VIC, 3083, Australia

    Sarah J. Spencer

  2. School of Medical Sciences, Health Innovations Research Institute (HIRi), RMIT University, Bundoora Campus, Melbourne, VIC, 3083, Australia

    Trisha A. Jenkins

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  1. Sarah J. Spencer
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Correspondence to Sarah J. Spencer .

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Editors and Affiliations

  1. Hudson Institute of Medical Research, Monash Medical Centre, The Ritchie Centre, Melbourne, Australia

    David W. Walker

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Spencer, S.J., Jenkins, T.A. (2016). Perinatal and Postnatal Determinants of Brain Development: Recent Studies and Methodological Advances. In: Walker, D. (eds) Prenatal and Postnatal Determinants of Development. Neuromethods, vol 109. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-3014-2_9

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  • DOI: https://doi.org/10.1007/978-1-4939-3014-2_9

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3013-5

  • Online ISBN: 978-1-4939-3014-2

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