Abstract
In vivo metabolic tests are highly valuable to determine whether atherosclerosis progression in mouse models is accompanied by carbohydrate metabolism alterations such as glucose intolerance and insulin resistance. In this chapter, we describe protocols to perform in the mouse glucose and insulin tolerance tests, two metabolic assays which evaluate the glucose tolerance and the insulin sensitivity, respectively.
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Acknowledgments
This work was supported by grants from the Carlos III Health Institute (CP10/00555, PI13/00834) and from the European Regional Development Fund (FEDER). H. González-Navarro is a “Miguel Servet” Program researcher, and A. Vinué received salary support from Proyecto Paula.
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Vinué, Á., González-Navarro, H. (2015). Glucose and Insulin Tolerance Tests in the Mouse. In: Andrés, V., Dorado, B. (eds) Methods in Mouse Atherosclerosis. Methods in Molecular Biology, vol 1339. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2929-0_17
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DOI: https://doi.org/10.1007/978-1-4939-2929-0_17
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-2928-3
Online ISBN: 978-1-4939-2929-0
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