Abstract
Transrectal ultrasound (TRUS) is one of the most frequently performed office procedures in urologist offices. However, the interpretation of the obtained images has not been fully utilized. During the TRUS procedure, unusual situations may be encountered. In addition, unusual patients, such as those who have previously undergone a radical prostatectomy or those without an anus, can be encountered. In this chapter, advanced techniques for prostate biopsy under such unusual situations are described. The second part of the chapter describes the underutilized TRUS staging for prostate cancer. TRUS will not show microscopic tumor extension beyond the capsule. However, careful examination of the prostate can detect subtle findings that suggest microscopic extension of the disease. By using such staging criteria for detecting microscopic tumor extension, the accuracy of TRUS staging can be significantly improved.
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Abbreviations
- ECE:
-
Extracapsular extension
- NPV:
-
Negative predictive value
- PPV:
-
Positive predictive value
- ROC:
-
Receiver-operating characteristic
- SVI:
-
Seminal vesicle invasion
- TRUS:
-
Transrectal ultrasound
References
Cancer Facts & Figures. 2014; http://www.cancer.org/acs/groups/content/@research/documents/webcontent/acspc-042151.pdf. Accessed 4 July 2014.
SEER Stat Fact Sheets: Prostate cancer. 2014; http://seer.cancer.gov/statfacts/html/prost.html. Accessed 5 July 2014.
Hodge KK, McNeal JE, Terris MK, et al. Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate. J Urol. 1989;142(1):71–4. discussion 74–5.
Stamey TA. Making the most out of six systematic sextant biopsies. Urology. 1995;45(1):2–12.
Freedland SJ, Amling CL, Terris MK, et al. Is there a difference in outcome after radical prostatectomy between patients with biopsy Gleason sums 4, 5, and 6? Results from the SEARCH database. Prostate Cancer Prostatic Dis. 2003;6(3):261–5.
Chang JJ, Shinohara K, Bhargava V, et al. Prospective evaluation of lateral biopsies of the peripheral zone for prostate cancer detection. J Urol. 1998;160(6 Pt 1):2111–4.
Freiha FS, McNeal JE, Stamey TA. Selection criteria for radical prostatectomy based on morphometric studies in prostate carcinoma. NCI Monogr. 1988;7:107–8.
Takashima R, Egawa S, Kuwao S, et al. Anterior distribution of Stage T1c nonpalpable tumors in radical prostatectomy specimens. Urology. 2002;59(5):692–7.
Meng MV, Franks JH, Presti Jr JC, et al. The utility of apical anterior horn biopsies in prostate cancer detection. Urol Oncol. 2003;21(5):361–5.
Franiel T, Stephan C, Erbersdobler A, et al. Areas suspicious for prostate cancer: MR-guided biopsy in patients with at least one transrectal US-guided biopsy with a negative finding–multiparametric MR imaging for detection and biopsy planning. Radiology. 2011;259(1):162–72.
Abd-Alazeez M, Ahmed HU, Arya M, et al. The accuracy of multiparametric MRI in men with negative biopsy and elevated PSA level-Can it rule out clinically significant prostate cancer? Urol Oncol. 2014;32(1):17–22.
Hambrock T, Somford DM, Hoeks C, et al. Magnetic resonance imaging guided prostate biopsy in men with repeat negative biopsies and increased prostate specific antigen. J Urol. 2010;183(2):520–7.
Chade DC, Shariat SF, Cronin AM, et al. Salvage radical prostatectomy for radiation-recurrent prostate cancer: a multi-institutional collaboration. Eur Urol. 2011;60(2):205–10.
Foster LS, Jajodia P, Fournier Jr G, et al. The value of prostate specific antigen and transrectal ultrasound guided biopsy in detecting prostatic fossa recurrences following radical prostatectomy. J Urol. 1993;149(5):1024–8.
Connolly JA, Shinohara K, Presti Jr JC, et al. Local recurrence after radical prostatectomy: characteristics in size, location, and relationship to prostate-specific antigen and surgical margins. Urology. 1996;47(2):225–31.
Shinohara K, Gulati M, Koppie TM, et al. Transperineal prostate biopsy after abdominoperineal resection. J Urol. 2003;169(1):141–4.
Rorvik J, Halvorsen OJ, Servoll E, et al. Transrectal ultrasonography to assess local extent of prostatic cancer before radical prostatectomy. Br J Urol. 1994;73(1):65–9.
Lorentzen T, Nerstrom H, Iversen P, et al. Local staging of prostate cancer with transrectal ultrasound: a literature review. Prostate Suppl. 1992;4:11–6.
Ebert T, Schmitz-Drager BJ, Burrig KF, et al. Accuracy of imaging modalities in staging the local extent of prostate cancer. Urol Clin North Am. 1991;18(3):453–7.
McSherry SA, Levy F, Schiebler ML, et al. Preoperative prediction of pathological tumor volume and stage in clinically localized prostate cancer: comparison of digital rectal examination, transrectal ultrasonography and magnetic resonance imaging. J Urol. 1991;146(1):85–9.
Scardino PT, Shinohara K, Wheeler TM, et al. Staging of prostate cancer. Value of ultrasonography. Urol Clin North Am. 1989;16(4):713–34.
Rosen MA, Goldstone L, Lapin S, et al. Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J Urol. 1992;148(2 Pt 1):331–7.
Ohori M, Egawa S, Shinohara K, et al. Detection of microscopic extracapsular extension prior to radical prostatectomy for clinically localized prostate cancer. Br J Urol. 1994;74(1):72–9.
Spirnak JP, Resnick MI. Clinical staging of prostatic cancer: new modalities. Urol Clin North Am. 1984;11(2):221–35.
Griffiths GJ, Clements R, Jones DR, et al. The ultrasound appearances of prostatic cancer with histological correlation. Clin Radiol. 1987;38(3):219–27.
Salo JO, Kivisaari L, Rannikko S, et al. Computerized tomography and transrectal ultrasound in the assessment of local extension of prostatic cancer before radical retropubic prostatectomy. J Urol. 1987;137(3):435–8.
Pontes JE, Eisenkraft S, Watanabe H, et al. Preoperative evaluation of localized prostatic carcinoma by transrectal ultrasonography. J Urol. 1985;134(2):289–91.
Ohori M, Scardino PT, Lapin SL, et al. The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol. 1993;17(12):1252–61.
Ohori M, Shinohara K, Wheeler TM, et al. Ultrasonic detection of non-palpable seminal vesicle invasion: a clinicopathological study. Br J Urol. 1993;72(5 Pt 2):799–808.
Perrapato SD, Carothers GG, Maatman TJ, et al. Comparing clinical staging plus transrectal ultrasound with surgical-pathologic staging of prostate cancer. Urology. 1989;33(2):103–5.
Andriole GL, Coplen DE, Mikkelsen DJ, et al. Sonographic and pathological staging of patients with clinically localized prostate cancer. J Urol. 1989;142(5):1259–61.
Rifkin MD, Zerhouni EA, Gatsonis CA, et al. Comparison of magnetic resonance imaging and ultrasonography in staging early prostate cancer. Results of a multi-institutional cooperative trial. N Engl J Med. 1990;323(10):621–6.
Hamper UM, Sheth S, Walsh PC, et al. Capsular transgression of prostatic carcinoma: evaluation with transrectal US with pathologic correlation. Radiology. 1991;178(3):791–5.
Wolf Jr JS, Shinohara K, Narayan P. Staging of prostate cancer. Accuracy of transrectal ultrasound enhanced by prostate-specific antigen. Br J Urol. 1992;70(5):534–41.
Gerber GS, Goldberg R, Chodak GW. Local staging of prostate cancer by tumor volume, prostate-specific antigen, and transrectal ultrasound. Urology. 1992;40(4):311–6.
Eisenberg ML, Cowan JE, Davies BJ, et al. The importance of tumor palpability and transrectal ultrasonographic appearance in the contemporary clinical staging of prostate cancer. Urol Oncol. 2011;29(2):171–6.
Ekici S, Ozen H, Agildere M, et al. A comparison of transrectal ultrasonography and endorectal magnetic resonance imaging in the local staging of prostatic carcinoma. BJU Int. 1999;83(7):796–800.
Jung AJ, Coakley FV, Shinohara K, et al. Local staging of prostate cancer: comparative accuracy of T2-weighted endorectal MR imaging and transrectal ultrasound. Clin Imaging. 2012;36(5):547–52.
Bates TS, Gillatt DA, Cavanagh PM, et al. A comparison of endorectal magnetic resonance imaging and transrectal ultrasonography in the local staging of prostate cancer with histopathological correlation. Br J Urol. 1997;79(6):927–32.
Presti Jr JC, Hricak H, Narayan PA, et al. Local staging of prostatic carcinoma: comparison of transrectal sonography and endorectal MR imaging. Am J Roentgenol. 1996;166(1):103–8.
Hardeman SW, Causey JQ, Hickey DP, et al. Transrectal ultrasound for staging prior to radical prostatectomy. Urology. 1989;34(4):175–80.
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Shinohara, K. (2015). Application of Prostate US for Advanced Techniques in Prostate Biopsy and Prostate Cancer Staging. In: Porter, C., Wolff, E. (eds) Prostate Ultrasound. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1948-2_13
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DOI: https://doi.org/10.1007/978-1-4939-1948-2_13
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