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Studies on the Mechanism of Phototoxicity of BAY y 3118 and Other Quinolones

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Biological Reactive Intermediates V

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 387))

Abstract

The quinolone antibiotic BAY y 3118 is a photochemically labile compound, and irradiation with UV-A light leads to its rapid decomposition. In vivo, following oral drug administration to guinea pigs, irradiation of the animals not only results in a severe local phototoxicity, but also leads to systemic phototoxic reactions [1].

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References

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© 1996 Springer Science+Business Media New York

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Schmidt, U., Schlüter, G. (1996). Studies on the Mechanism of Phototoxicity of BAY y 3118 and Other Quinolones. In: Snyder, R., et al. Biological Reactive Intermediates V. Advances in Experimental Medicine and Biology, vol 387. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-9480-9_16

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  • DOI: https://doi.org/10.1007/978-1-4757-9480-9_16

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-9482-3

  • Online ISBN: 978-1-4757-9480-9

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