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The Pharmacokinetics of Cadmium in the Dually Perfused Human Placenta

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Cellular Biology and Pharmacology of the Placenta

Part of the book series: Trophoblast Research ((TR))

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Abstract

Cadmium is reported to be a significant occupational hazard to over 100,000 workers employed in the mining and processing of this metal (NIOSH publication number 76–192). Because cadmium is released into the environment by mining and numerous manufacturing processes, the general population is exposed to cadmium in air, food, and water (Friberg et al., 1974; Nriagu, 1982). Cigarette smoking is, in addition, an important route of exposure to cadmium (Friberg et al., 1974). The occurrence of exposure to cadmium in the general population has been documented by analyses of the cadmium content in human tissue (Gross et al., 1976). Cadmium is found in human placentae at levels from 0.04 to 1.6 nmole Cd/g (Miller and Shaikh, 1983)

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Wier, P.J., Miller, R.K. (1987). The Pharmacokinetics of Cadmium in the Dually Perfused Human Placenta. In: Miller, R.K., Thiede, H.A. (eds) Cellular Biology and Pharmacology of the Placenta. Trophoblast Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-1936-9_26

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  • DOI: https://doi.org/10.1007/978-1-4757-1936-9_26

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4757-1938-3

  • Online ISBN: 978-1-4757-1936-9

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