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Nechanism of Substance P-Induced Salivary Secretion in Rats

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Book cover Kinins—II

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 120))

Abstract

Leeman and Hammerschlag (1,2) found a potent sialogogic substance in the rough extract from bovine or rat hypothalamus. This sialogogue has been known to be substance P itself. Although substance P (SP), one of tachykinins, has been recognized as a neurotransmitter (3,4) or a modulator (5,6) of the primary sensory neurone, mechanism of sialogogic action of this substance still remained undissolved.

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References

  1. Hammerschlag, R. and Leeman, S.E., 1966, Induction of salivation a bovirie hypothalamic factor, Fed. Ploc. 25, 192.

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  2. Leeman, S.E. and Hammerschlag, R., 1967, Stimulation of salivary secretion by a factor extracted from hypothalamic tissue, Endocrinol. 81, 803.

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  3. Lembeck, F.N.S., 1953, Zur Frage der zentralen flbertragung afferenter Impulse. Das Vorkommen und die Bedeutung der Substanz P in den dorsalen Wurzeln des Rückenmarks, Arch. Pharmacol. 219, 197.

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  4. Otsuka, M. and Konishi, S., 1976, Substance P and Excitatory transmitter of primary sensory neurons, Cold Spring Harbor Symp. Qua.nt. Biol. XL, 135.

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  5. Pïrivoy, W., Lane, M. and Kroeger, D., 1963 The actions of certain polypeptides on synaptic transmission, Ann N. Y. Acad. Scia 104, 312.

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  6. Hedqvist, P. and von Euler, U.S., 1977, Effects of substance P on some autonomic neuroeffector junctions, in Substance P eds. U.S.von Euler and B. Pernow ( Raven Press, New York ) p. 89.

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  7. Hökfelt, T., Johansson, O., Kellerth, J.-G., Ljungdahl, Nilsson, G., Nyards, A. and Pernow, B., 1977, Immunohistochemical distribution of substance P, in Substance P eds, U.S. von Euler and B. Pernow ( Raven Press, New York ) p. 117.

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Author information

Authors and Affiliations

  1. Department of Pharmacology, Osaka University Dental School, Osaka 530, Japan

    R. Inoki, T. Kudo, Y. Kotani, M. Oka, K. Iwatsubo & K. Matsumoto

Authors
  1. R. Inoki
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  2. T. Kudo
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  3. Y. Kotani
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  4. M. Oka
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  5. K. Iwatsubo
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  6. K. Matsumoto
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Editor information

Editors and Affiliations

  1. Institute for Protein Research, Osaka University, Osaka, Japan

    Setsuro Fujii

  2. Science University of Tokyo, Tokyo, Japan

    Hiroshi Moriya

  3. Meiji College of Pharmacy, Tokyo, Japan

    Tomoji Suzuki

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© 1979 Springer Science+Business Media New York

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Inoki, R., Kudo, T., Kotani, Y., Oka, M., Iwatsubo, K., Matsumoto, K. (1979). Nechanism of Substance P-Induced Salivary Secretion in Rats. In: Fujii, S., Moriya, H., Suzuki, T. (eds) Kinins—II. Advances in Experimental Medicine and Biology, vol 120. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-0926-1_37

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  • DOI: https://doi.org/10.1007/978-1-4757-0926-1_37

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4757-0928-5

  • Online ISBN: 978-1-4757-0926-1

  • eBook Packages: Springer Book Archive

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