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Structure and Function of Gangliosides pp 213–226Cite as

Biosynthesis of Gangliosides in Tissues

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 125))

Abstract

The presence of neuraminic acid-containing glycosphingolipids (gangliosides) in mammalian (1–5) and avian (6) tissues has been known for the last 40 years. Recently the chemical structures of 20 different gangliosides isolated from neural (7–9) and non-neural (10–12) tissues have been elucidated. In addition to the hexosaminefree and N-acetylgalactosamine-containing gangliosides, the structures of at least 3 different gangliosides (13–18) containing nLcOse4Cer (Gal(β1–4)G1cNAc(β1–3)Gal(β1–4) Glc-Ceramide) as the core structure have been reported by several laboratories.

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Author information

Author notes

  1. Jao-Long Chien

    Present address: Department of Neurology, Medical University of South Carolina, Charleston, S.C., 29403, USA

Authors and Affiliations

  1. Department of Chemistry, Biochemistry and Biophysics Program, Univ. of Notre Dame, Notre Dame, IN, 46556, USA

    Subhash Basu, Manju Basu, Jao-Long Chien & Kathleen A. Presper

Authors
  1. Subhash Basu
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  2. Manju Basu
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  3. Jao-Long Chien
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  4. Kathleen A. Presper
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Editor information

Editors and Affiliations

  1. Psychiatric Research Centre, Department of Neurochemistry, St. Jörgen Hospital, Göteborg, Sweden

    Lars Svennerholm

  2. C. N. R. S. Center for Neurochemistry, Strasbourg, France

    Paul Mandel , Henri Dreyfus  & Paul-Francis Urban ,  & 

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© 1980 Plenum Press, New York

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Basu, S., Basu, M., Chien, JL., Presper, K.A. (1980). Biosynthesis of Gangliosides in Tissues. In: Svennerholm, L., Mandel, P., Dreyfus, H., Urban, PF. (eds) Structure and Function of Gangliosides. Advances in Experimental Medicine and Biology, vol 125. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7844-0_21

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  • DOI: https://doi.org/10.1007/978-1-4684-7844-0_21

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7846-4

  • Online ISBN: 978-1-4684-7844-0

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