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Comparison of Intracellular PO2 and Conditions for Blood-Tissue O2 Transport in Heart and Working Red Skeletal Muscle

  • Chapter
Oxygen Transport to Tissue IX

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 215))

Abstract

Recent measurements (Honig et al., 1984; Gayeski, Connett and Honig, 1985; Gayeski and Honig, 1986) and mathematical models (Hellums, 1977; Clark et al., 1985; Federspiel and Popel, in press; Groebe and Thews, 1986) indicate that the principal resistance to O2 mass transfer is at the capillary under conditions of high O2 flux. Federspiel and Popel (in press) have described this behaviour by relating the transcapillary O2 flux to a driving force. The factor of proportionality is a mass transfer coefficient homologous to a conductance:

$$J=C\times\left[Pcap{{O}_{2}}-Pcell{{O}_{2}}\right]$$
(1)

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Authors and Affiliations

  1. School of Medicine and Dentistry, The University of Rochester, 601 Elwood Avenue, Rochester, NY, 14642, USA

    C. R. Honig & T. E. J. Gayeski

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  1. C. R. Honig
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  2. T. E. J. Gayeski
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Editors and Affiliations

  1. The Medical School, University of Bristol, Bristol, UK

    I. A. Silver  & A. Silver  & 

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© 1987 Plenum Press, New York

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Honig, C.R., Gayeski, T.E.J. (1987). Comparison of Intracellular PO2 and Conditions for Blood-Tissue O2 Transport in Heart and Working Red Skeletal Muscle. In: Silver, I.A., Silver, A. (eds) Oxygen Transport to Tissue IX. Advances in Experimental Medicine and Biology, vol 215. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7433-6_36

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  • DOI: https://doi.org/10.1007/978-1-4684-7433-6_36

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7435-0

  • Online ISBN: 978-1-4684-7433-6

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