Abstract
In recent years, detailed information has been accumulated 1,2,3, that cellular, as well as humoral, immune responses play an important role in the clearing of influenza virus and in the recovery phase of infection. On the other hand, influenza virus, such as many viruses, during the acute stages of infection is able to inhibit cellular immune functions as shown by Reiss, and Rodgers5. Little is known about this mechanism of immunosuppression.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ada G.L., Leung K.N., Ertl H.C.: An analysis of effector T cell generation and function in mice exposed to Influenza A or Sendai viruses. Immunol.Rev., 58, 5, (1981).
Daisy J.A., Toipin M.D., Quinnan G.V., Rook A.H., Murphy B.R., Mitthal K., Clemenis M.L., Mullinlx M.G., Kiley S.C., Ennis F.A.: Influenza A infection in human volunteers, pag.443 in The replication of negative strand virus, Bishop, D.M.L., Compans, R.W. Ed., Elsevier, North-Holland, (1981).
Ennis A.: Some newly recognized aspects of resistence against and recovery from influenza. Archives of Virology, 73, 207, (1982).
Reiss C,S., Schul man J.L.: Cellular Immune Responses of Mice to Influenza Virus Infection., Cellular Immunology, 56, 502, (1980).
Rodgers B., Mins CA.: Interaction of Influenza Virus with mouse macrofages. Infect. Immun., 31, 751, (1981).
Garaci E. , Caliò R. , Djaczenko W. : Effect of Influenza virus PR8 infection on thymus in Intarrt and adrenolectomized mice. Experentia, 30, 358, (1974).
Gillis S., Ferm M.M. Ou W., Smith KA.: T-cell growth factor: parameters of production and a quantitative microassay for activity. J. Immunol., 120, 2027, (1978).
Herberman RB. and Ortaldo J.R.: Natural killer cells: their role in defenses against disease. Science, 24, 214, (1981).
Wysocki L.J. and Sato V.L.: “Panning” for lymphocytes: A method for cell selection. Proc. Natl . Acad. Sci. USA, 75, 2844, (1978).
Hurwitz J.L. and Hackett C.J.: Influenza-specific suppression: contribution of major viral proteins to the generation and function of T suppressor cells. J.Immunology, 135, 2134, (1985).
Chouaib S., Chatenoud L., Klatzmann D. and Fradelizi D.: The mechanisms of inhibition of human IL-2 production. J.Immunology, 132, 1851, (1984).
Chouaib S. and Fradelizi D.: The mechanism of inhibition of human IL-2 production. J.Immunology, 129, 2463, (1982).
Wainberg M.A., Spira B., Boushira M. and Margolese R.G.: Inhibition by human T-lymphotropic virus (HTLV-I) of T-lymphocyte mitogenesis: failure of exogenous T-cell growth factor to restore responsiveness to lectin. Immunology, 54, 1, (1985).
Blackett S. and Minis C.A.: Studies of depressed interleukin-2 production by spleen cells from mice following infection with cytomegalovirus. Arch. Virol. 99, 1, (1988)
Colonna Romano G., Dieli F., Abrignani S., Salerno A. and Colizzi V.: Inhibition of lymphocyte mitogenesis in mice infected with Newcastle disease virus: viral interference with the interleukin system. Immunology, 57, 373, (1986).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Plenum Press, New York
About this paper
Cite this paper
Del Gobbo, V., Balestra, E., Marini, S., Villani, N., Caliò, R. (1989). Influenza Virus Infection Reduces Cellular Immunity Functions. In: Askonas, B.A., Moss, B., Torrigiani, G., Gorini, S. (eds) The Immune Response to Viral Infections. Advances in Experimental Medicine and Biology, vol 257. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5712-4_24
Download citation
DOI: https://doi.org/10.1007/978-1-4684-5712-4_24
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-5714-8
Online ISBN: 978-1-4684-5712-4
eBook Packages: Springer Book Archive