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Calcium Protein Signaling pp 155–164Cite as

Activation of Rabbit Skeletal Muscle Myosin Light Chain Kinase by Calmodulin- A Mechanistic Overview

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 255))

Abstract

The myosin light chain kinases [MLCK, E.C. 2.7.1.37] are a family of tissue-specific isozymes which share as their substrate the phosphoryl- or P-light chain.component of myosin. Distinct forms of MLCK have been isolated from smooth, skeletal, and cardiac muscle. The enzyme appears to be ubiquitous, with non-muscle MLCK envisaged as being very similar, if not identical, to the smooth muscle isozyme (For a review see (43)).

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Author information

Authors and Affiliations

  1. Howard Hughes Medical Institute, University of Washington, Seattle, Washington, 98195, USA

    Peter J. Kennelly & Edwin G. Krebs

  2. Department of Biochemistry, University of Washington, Seattle, Washington, 98195, USA

    Melissa Starovasnik & Edwin G. Krebs

  3. Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA

    Edwin G. Krebs

Authors
  1. Peter J. Kennelly
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  2. Melissa Starovasnik
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  3. Edwin G. Krebs
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Editor information

Editors and Affiliations

  1. Nagoya University, Nagoya, Japan

    H. Hidaka

  2. Swiss Federal Institute of Technology, Zurich, Switzerland

    E. Carafoli

  3. Baylor College of Medicine, Houston, Texas, USA

    A. R. Means

  4. Mie University School of Medicine, Mie, Japan

    T. Tanaka

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© 1989 Plenum Press, New York

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Kennelly, P.J., Starovasnik, M., Krebs, E.G. (1989). Activation of Rabbit Skeletal Muscle Myosin Light Chain Kinase by Calmodulin- A Mechanistic Overview. In: Hidaka, H., Carafoli, E., Means, A.R., Tanaka, T. (eds) Calcium Protein Signaling. Advances in Experimental Medicine and Biology, vol 255. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5679-0_17

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  • DOI: https://doi.org/10.1007/978-1-4684-5679-0_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5681-3

  • Online ISBN: 978-1-4684-5679-0

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