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Catecholamine Metabolism and Digital Circulation after Histamine and Its Analogue

Krypton Clearance and Calorimetric Blood Flow

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Book cover Oxygen Transport to Tissue

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 37B))

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Abstract

In 1959 (1) we reported the paradoxical effects on the digital circulation of histamine administered parenterally and of an orally ingested histamine analogue* (2). Both histamine and its analogue produced vasodilatation of the capillaries as manifested by flushing contrasted with vasoconstriction of the arteriovenous anastomoses (AVAS). It was postulated at that time that the AVA constricted in response to heat loss produced by histamine-mediated precapillary sphincter and hence capillary vasodilatation. The question as to whether the AVA constriction was a neural reflex or produced by some other mechanism such as the release of catecholamines (CM) from nerve endings and/or chrcmaff in tissues remained unanswered (3).

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References

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Author information

Authors and Affiliations

  1. Laboratory of Biochemical Pharmacology, Institute of Rehabilitation Medicine, New York University Medical Center, New York, N.Y., 10016, USA

    Nosrat Eric Naftchi & Edward W. Lowman

  2. The Department of Medicine, The Mount Sinai School of Medicine, The City University of New York, N.Y., 10029, USA

    Milton Mendlowitz & Stefan Racoceanu

Authors
  1. Nosrat Eric Naftchi
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  2. Milton Mendlowitz
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  3. Stefan Racoceanu
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  4. Edward W. Lowman
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Editor information

Editors and Affiliations

  1. Clemson University, Clemson, South Carolina, USA

    Duane F. Bruley (Professor of Chemical Engineering) (Professor of Chemical Engineering)

  2. University of Arkansas Medical Center, Little Rock, Arkansas, USA

    Haim I. Bicher (Associate Professor of Pharmacology) (Associate Professor of Pharmacology)

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© 1973 Plenum Press, New York

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Naftchi, N.E., Mendlowitz, M., Racoceanu, S., Lowman, E.W. (1973). Catecholamine Metabolism and Digital Circulation after Histamine and Its Analogue. In: Bruley, D.F., Bicher, H.I. (eds) Oxygen Transport to Tissue. Advances in Experimental Medicine and Biology, vol 37B. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-5089-7_9

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  • DOI: https://doi.org/10.1007/978-1-4684-5089-7_9

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4684-5091-0

  • Online ISBN: 978-1-4684-5089-7

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