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Inhibition of Oxidative Damage of Red Blood Cells and Liver Tissue by Genistein-8C-Glucoside

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Biological Reactive Intermediates VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 500))

Abstract

Genistein belongs to isoflavons, a subclass of flavonoids, the large group of polyphenolic compounds widely distributed in plants. A number of studies show a protective effect of flavonoids against cancer, toxic liver injury and cardiovascular diseases1. Being phytoestrogen, genistein has recently generated interest as a potential anticancer and antiatherogenic agent2. Several flavonoids are known as antioxidants and scavengers of free oxygen radicals3.The antiatherogenic effect of isoflavons is associated with inhibition of myeloperoxidase in phagocytic cells producing of hypo-chlorite, a highly reactive chlorinated species4.

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Author information

Authors and Affiliations

  1. Institute of Biochemistry, Grodno, Belarus

    Vyacheslav Buko, Lev Zavodnik, Ilya Zavodnik, Elena Lapshina & Alina Shkodich

  2. Insitute of Experimental Botanics, Minsk, Belarus

    Nikolai Laman

  3. Institute of Biophysics, University of Lodz, Poland

    Maria Bryszewska

Authors
  1. Vyacheslav Buko
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  2. Lev Zavodnik
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  3. Ilya Zavodnik
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  4. Elena Lapshina
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  5. Alina Shkodich
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  6. Nikolai Laman
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  7. Maria Bryszewska
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Editor information

Editors and Affiliations

  1. Université René Descartes, Paris, France

    Patrick M. Dansette

  2. Rutgers University and The Environmental & Occupational Health Sciences Institute, Piscataway, New Jersey, USA

    Robert Snyder

  3. CNRS, Paris, France

    Marcel Delaforge

  4. University of Surrey, Guildford, Surrey, England

    G. Gordon Gibson

  5. Institute of Toxicology and Environmental Health, The Technical University of Munich, Munich, Germany

    Helmut Greim

  6. Medical University of South Carolina, Charleston, South Carolina, USA

    David J. Jollow

  7. University of Texas, Austin, Texas, USA

    Terrence J. Monks

  8. University of Arizona, Tucson, Arizona, USA

    I. Glenn Sipes

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© 2001 Springer Science+Business Media New York

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Buko, V. et al. (2001). Inhibition of Oxidative Damage of Red Blood Cells and Liver Tissue by Genistein-8C-Glucoside. In: Dansette, P.M., et al. Biological Reactive Intermediates VI. Advances in Experimental Medicine and Biology, vol 500. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0667-6_43

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  • DOI: https://doi.org/10.1007/978-1-4615-0667-6_43

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5185-6

  • Online ISBN: 978-1-4615-0667-6

  • eBook Packages: Springer Book Archive

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