Abstract
The processes of lipid peroxidation (LPO) in cell membranes modify effectively the lipid structure of biomembranes and the activity of drug-metabolizing enzyme systems (DMES) and specially cytochrome P-450-dependent microsomal monooxygenase (Mannering 1981). Reactive oxygen species (ROS) are generated in this system leading to chain development of LPO processes.
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References
Brave, A., Pearson, S., 1962, Statistical methods in biology, N. Bayleys. ed., New York
Chetverikova, L.K and Inozemtseva, L.I., 1996, Role of lipid peroxidation in thepathogenesis of the influenza and search for antivial protective agents, Vestn. Ross. Acad. Med. Nauk, 3: 37
Eisen, H.J., 1986, Induction of hepatic P-450 izozymes. Evidens for specific receptors, in: Cytochrome P-450 Structure, Mechanism and Biochemistry. P.R.O. de Montallano. ed., Plenum Press, New York
Farrell, G.C., 1987, Drug metabolism in extrahepatic diseases. Pharmacol. Ther., 35: 375
Folch, J., Lees, M., Shoane-Stoaley, C.H., 1957, A simple methods for the isolation and puritification of total lipid from animal tissue, J. Biol. Chem., 226: 497
Gorbunov, N.V., Volgarev, A.P., Bykova, N.O., Prozorovskaia, M.P., 1992, Microsomal hydroxilating system of the mouse liver in toxic form of influenza infection, Bull. Exp. Biol. Med. July, 114(7): 44
Kiselev, O.I, Isakov, V.F.A, Sharonov, B.P, Sukhinin, V.P., 1994, Pathogenesis of severe influenza, Vesn. Ross. Acad. Med. Nauk., 9: 32
Mannering, G.J., 1981, Hepatic cytochrome P-450-linked drug metabolizing systems, in: Concepts in Drug Metabolism. P. Jenner and B. Testa. eds., Marcel Dekker, New York
Matsubara, N., Koike, M., Touchi, A., Tochino, Y., Sugeno, K., 1976, Quantative determination of cytochrome P-450 in rat liver homogenate, Anal.Biochem. 75 (2): 596
Mazel, P., 1971, Experiments illustrating drug metabolism in vitro-determination of microsomal of aniline hydroxylase, in: Fundamentals of Drug Metabolism and Drug Disposition. La Du B.N., Mandel H.G., Way E.L. eds, The Willkins Co, Baltimore
Nash, T., 1953, The colometric estimation of formaldehyde by means of the Hautch reaction, J. Biol. Chem. 55: 416
Peterhans, E., 1997, Reactive oxygen species and nitric oxyde in viral diseases, Biol. Trace Element Research, 56: 107
Pokhillko, A.V, Kramskaia, T.A, Poliak, R.I., 1995, Stress and viral infection: dynamics of expression of influenza A virus agents during immobilization stress, Vopr-Virusol., Mar-Apr 40(2): 76
Rechnagel, R. and Glende, E., 1984, Spectrophotometric detection of lipid conjugated diens, Meth. Enzymol. 105: 331
Roering, D. L., Mascaro, L., Aust, S., 1972, Microsomal electron transport: tetrafolium reduction by rat liver microsomal NADP.H-cytochrome c-reductase. Arch. Biochem. 153: 475
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Stoeva, E., Tantcheva, L., Mileva, M., Savov, V., Galabov, A.S., Braykova, A. (2001). Preventive Effect of Vitamin E on the Processes of Free Radical Lipid Peroxidation and Monooxygenase Enzyme Activity in Experimental Influenza Virus Infection. In: Dansette, P.M., et al. Biological Reactive Intermediates VI. Advances in Experimental Medicine and Biology, vol 500. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0667-6_40
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DOI: https://doi.org/10.1007/978-1-4615-0667-6_40
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