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Biochemical Evidence on the Role of Gangliosides in Nerve-Endings

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Ganglioside Function

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 71))

Abstract

The nervous system, compared to other tissues, is characterized by high ganglioside levels, most particularly of the tri- and tetra-sialogangliosides (WIEGANDT, 1968). This simple fact has led to many suggestions that gangliosides must have a neuro-specific function to match their neurospecific concentration and pattern. The purpose of this article is to examine the evidence that the gangliosides have a role in synaptic function, since it is at the synaptic region that the gangliosides seem to be concentrated.

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Authors and Affiliations

  1. Department of Behavioural Biology, Research School of Biological Sciences, Australian National University, P.O. Box 475, Canberra City, ACT, 2601, Australia

    I. G. Morgan

  2. Istituto di Chimica Biologica, Università di Milano, Via Saldini, 50, Milano, 20133, Italia

    G. Tettamanti

  3. Centre de Neurochimie du CNRS, 11 rue Humann, 67085, Strasbourg Cédex, France

    G. Gombos

Authors
  1. I. G. Morgan
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  2. G. Tettamanti
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  3. G. Gombos
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Editors and Affiliations

  1. The Medical School, University of Perugia, Perugia, Italy

    Giuseppe Porcellati

  2. The Medical School, University of Milan, Milan, Italy

    Bruno Ceccarelli  & Guido Tettamanti  & 

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Morgan, I.G., Tettamanti, G., Gombos, G. (1976). Biochemical Evidence on the Role of Gangliosides in Nerve-Endings. In: Porcellati, G., Ceccarelli, B., Tettamanti, G. (eds) Ganglioside Function. Advances in Experimental Medicine and Biology, vol 71. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4614-9_9

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  • DOI: https://doi.org/10.1007/978-1-4614-4614-9_9

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