Summary
Mass spectrometry of intact ganglioside derivatives has been shown to afford a specific information on type, number and sequence of sugars, as well as ceramide structure. This is illustrated here for a hematoside with N-glycolylneuraminic acid and a di-sialyldihexosylceramide. As shown elsewhere, this novel technique, needing only 10 micrograms for a spectrum, is generally applicable to all types of glycolipids, including complex blood group fuco-lipids.
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References
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Karlsson, KA. (1976). On a Molecular, Microscale Fingerprinting of Gangliosides. In: Porcellati, G., Ceccarelli, B., Tettamanti, G. (eds) Ganglioside Function. Advances in Experimental Medicine and Biology, vol 71. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-4614-9_2
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DOI: https://doi.org/10.1007/978-1-4614-4614-9_2
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