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Benign Diseases of the Vulva

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Abstract

The external female genitalia include the mons pubis, labia majora and minora, clitoris, and vestibule. The mons is the portion of hair-bearing skin and associated subcutaneous tissue overlying the pubic symphysis. Inferior to the pubis, the hair-bearing skin of the mons divides into two folds, the labia majora, which join posteriorly at the perineal body, just anterior to the anus. Medial to the labia majora are a second set of folds, the labia minora, each of which divides at the anterior end into two sets of smaller folds. The superior folds fuse in the midline anterior to the clitoris, forming the prepuce, or clitoral hood, and the inferior folds fuse in the midline posterior to the clitoris, forming the frenulum. Posteriorly, the labia minora fuse without further divisions, at the fourchette, posterior to the introitus and anterior to the perineal body. The clitoris consists of a bundle of erectile tissue situated in the midline, with just the tip, or glans, visible between the prepuce and frenulum. Beneath the surface is the body of the clitoris which branches at the base into two crurae running along the pubic rami in the deep soft tissue. The vestibule is a roughly diamond shaped area bounded anteriorly by the frenulum of the clitoris, laterally by the medial edges of the labia minora and posteriorly by the fourchette. Posterior to the frenulum on the vestibule is the urethral orifice, and posterior to that lies the vaginal opening, bounded by the hymen or remnants thereof. The external anatomy is illustrated in Fig. 1.

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References

  • Abdul-Cadir J, Catania L, Hindin MJ, Say L, Petignat P, Abdulcadir O (2016) Female genital mutilation: a visual reference and learning tool for health care professionals. Obstet Gynecol 128:958–963

    Article  Google Scholar 

  • Abou M, Dallenbach P (2013) Acute cervicitis and vulvovaginitis may be associated with cytomegalovirus. BMJ Case Rep. https://doi.org/10.1136/bcr-2013-008884

  • Abreu-dos-Santos F, Camara S, Reis F, Freitas T, Gaspar H, Cordeiro M (2016) Vulvar lobular capillary hemangioma: a rare location for a frequent entity. Case Rep Obstet Gynecol. https://doi.org/10.1155/2016/3435270

  • Ahronowitz I, Harp J, Shinkai K (2012) Etiology and management of pyoderma gangrenosum. Am J Clin Dermatol 13:191–211

    Article  PubMed  Google Scholar 

  • Akopians AL, Rapkin AJ (2015) Vulvodynia: the role of inflammation in the etiology of localized provoked pain of the vulvar vestibule (vestibulodynia). Semin Reprod Med 33:239–245

    Article  PubMed  Google Scholar 

  • Al-Ojaimi EH, Abdulla MM (2012) Giant epidermoid inclusion cyst of the clitoris mimicking clitoromegaly. J Lower Gen Tract Dis 17:58–60

    Article  Google Scholar 

  • Ali H, Guy RJ, Wand H, Read TH, Regan DG, Grulich AE, Fairley CK, Donovan B (2013) Decline in in-patient treatments of genital warts among young Australians following the national HPV vaccination program. BMC Infect Dis 13:140. http://www.biomedcentral.com/17471-2334/13/140

    Article  PubMed Central  PubMed  Google Scholar 

  • Allen AL, Siegfried EC (1998) The natural history of condyloma in children. J Am Acad Dermatol 39:951–955

    Article  CAS  PubMed  Google Scholar 

  • Anderson-Mueller BE, Laudenschlager MD, Hansen KA (2009) Epidermoid cyst of the clitoris: an unusual cause of clitoromegaly in a patient without history of previous female circumcision. J Pediatr Adolesc Gynecol 22:e130–e132

    Article  PubMed  Google Scholar 

  • Andreassi L, Bilenchi R (2014) Non-infectious inflammatory genital lesions. Clin Dermatol 32:307–314

    Article  PubMed  Google Scholar 

  • Arkwright PD, Cassim M, Subramanian H, Spergel J, Schneider LC, Wollenberg A (2013) Management of difficult-to-treat atopic dermatitis. J Allergy Clin Immunol 1:142–151

    Article  Google Scholar 

  • Asante A, Omurtag K, Roberts C (2010) Epidermal inclusion cyst of the clitoris 30 years after female genital mutilation. Fertil Steril 94:e1–e3

    Article  Google Scholar 

  • Atzmony L, Hodak E, Leshem YA, Rosenbaum O, Gdalevich M, Anhalt GJ, Mimouni D (2015) The role of adjuvant therapy in pemphigus: a systemic review and meta-analysis. J Am Acad Dermatol 73:264–271

    Article  PubMed  Google Scholar 

  • Aydin Y, Atis A, Polat N (2011) Bilateral endometrioma of Bartholin glands accompanying ovarian endometrioma. J Obstet Gynaecol 31:187–189

    Article  CAS  PubMed  Google Scholar 

  • Baandrup L, Blomberg M, Dehlendorff C, Sand C, Andersen K, Kjaer S (2013) Significant decrease in the incidence of genital warts in young Danish women after implementation of a national human papillomavirus vaccination program. Sex Transm Dis 40:130–135

    Article  PubMed  Google Scholar 

  • Bai H, Cviko A, Granter S, Yuan L, Betensly R, Crum C (2003) Immunophenotype and viral (human papillomavirus) correlates of vulvar seborrheic keratosis. Hum Path 34:559–564

    Article  PubMed  Google Scholar 

  • Baker GM, Selim A, Hoang MP (2013) Vulvar adnexal lesions: a 32 year, single institution review from Massachusetts General Hospital. Arch Pathol Lab Med 137:1237–1246

    Article  PubMed  Google Scholar 

  • Balfour FJT, Vincenti AC (1991) Idiopathic vulvar calcinosis. Histopathology 18:183–184

    Article  CAS  PubMed  Google Scholar 

  • Ball RA, Edwards L, Reutter JC, West KL, Selim MA (2015) Inflammatory disorders affecting the epidermis of the vulva. In: Hoang, Selim (eds) Vulvar pathology. Springer, New York, pp 31–69

    Google Scholar 

  • Barbosa NDF, de Aguiar LM, Maruta CW, Aoki V, Sotto MN, Labinas GHO, Perigo AM, Santi CG (2012) Vulvo-vaginal manifestations and evaluation of Papanicolou smears in pemphigus vulgaris and pemphigus foliaceous. J Am Acad Dermatol 67:409–416

    Article  Google Scholar 

  • Barret M, de Parades V, Battistella M, Sokol H, Lemarchand N, Marteau P (2013) Crohn's disease of the vulva. J Crohn’s Colitis 8:563–570

    Article  Google Scholar 

  • Bast-Juzbasic A, Ceovic R (2014) Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection and molluscum contagiosum. Clin Dermatol 32:290–298

    Article  Google Scholar 

  • Bauer A, Rodiger C, Greif C, Kaatz M, Elsner P (2005) Vulvar dermatoses-irritant and allergic contact dermatitis of the vulva. Dermatology 210:143–149

    Article  CAS  PubMed  Google Scholar 

  • Biswas A, Cooper J, Latifaj B (2007) Metastatic calcinosis cutis presenting as bilateral vulval cysts. Brit J Dermatol 157:622–624

    Article  CAS  Google Scholar 

  • Bornstein J, Goldstein AT, Stockdale CK, Bergeron S, Pukall C, Zolnoun D, Coady D (2016) 2015 ISSVD, ISSWSH and IPPS consensus terminology and classification of persistent vulvar pain and vulvodynia. Obstet Gynecol 127:745–751

    Article  PubMed  Google Scholar 

  • Brenn T (2011) Atypical genital nevus. Arch Pathol Lab Med 135:317–320

    PubMed  Google Scholar 

  • Buda A, Ferrari L, Marra C, Passoni P, Perego P, Milani R (2008) Vulvar endometriosis in surgical scar after excision of the Bartholin gland: report of a case. Arch Gynecol Obstet 277:255–256

    Article  PubMed  Google Scholar 

  • Carlson JA, Mu XC, Slominski A, Weismann K, Crowson AN, Malfetano J, Prieto V, Mihm M (2002) Melanocytic proliferations associated with lichen sclerosus. Arch Dermatol 138:77–87

    Article  PubMed  Google Scholar 

  • Carter J, Elliott P, Russel P (1992) Bilateral fibroepithelial polyps of labium minus with atypical stromal cells. Pathology 24:37–39

    Article  CAS  PubMed  Google Scholar 

  • Cetinkurson S, Narci A, Sahin O, Ozcara E (2009) Epidermoid cyst causing clitoromegaly in a child. Int J Gynaecol Obstet 105:64

    Article  Google Scholar 

  • Chan C, Chiu H (2008) Vestibular papillomatosis. NEJM 358:1485

    Google Scholar 

  • Chang M, Newman C, Davis MDP, Lehman JS (2016) Acquired lymphangiectasia (lymphangioma circumscriptum) of the vulva: clinicopathologic study of 11 patients from a single institution and 67 from the literature. Int J Dermatol 55:e482–e487

    Article  PubMed  Google Scholar 

  • Chen W, Koenig C (2004) Vulvar keratoacanthoma: a report of two cases. Int J Gynecol Path 23:284–286

    Article  Google Scholar 

  • Cilla G, Pico F, Peris A, Idigoras P, Urbieta M, Perez-Trallero E (1992) Human genital myiasis due to Sarcophaga. Rev Clín Esp 190:189–190

    PubMed  CAS  Google Scholar 

  • Coghill SB, Tyler X, Shaxted EJ (1990) Benign mucinous metaplasia of the vulva. Histopathol 17:373–375

    Article  CAS  Google Scholar 

  • Cohen SE, Klausner JD, Engelman J, Philip S (2013) Syphylis in the modern era. Infect Dis Clin N Am 27:705–722

    Article  Google Scholar 

  • Conces MR, Williamson SR, Montironi R, Lopez-Beltran A, Scarpelli M, Cheng L (2012) Urethral caruncle: clinicopathologic features of 41 cases. Hum Path 43:1400–1404

    Article  PubMed  Google Scholar 

  • Connor CJ, Eppsteiner EE (2014) Vulvar contact dermatitis. Proc Obstet Gynecol 4: 1. Available from http://ir.uiowa.edu/pog/

  • Cooper SM, Wojnarowska F (2006) Influence of treatment on erosive lichen planus of the vulva and its prognosis. Arch Dermatol 142:289–294

    PubMed  Google Scholar 

  • Dabade TS, Davis MDP (2011) Diagnosis and tretment of the neutrophilic dermatoses (pyoderma gangrenosum, Sweet's syndrome). Dermatol Therapy 24:273–284

    Article  Google Scholar 

  • Day T, Scurry J (2014) Vulvar Pityriasis versicolor in an immunocompetent woman. J Lower Gen Tract Dis 18:e71–e73

    Article  Google Scholar 

  • Dereli T, Turk BG, Kazandi AC (2007) Syringomas of the vulva. Int J Gynaecol Obstet 99:65–66

    Article  CAS  PubMed  Google Scholar 

  • Domfeh AB, Silasi DA, Lindo F, Parkash V (2012) Chronic hypertrophic vulvar herpes simulating neoplasia. Int J Gyneco Pathol 31:33–37

    Article  Google Scholar 

  • Duan D, Stevenson ML, Malter LB, Pomeranz MK (2014) Cutaneous Crohn’s disease of the vulva. BMJ Case Rep 2014. https://doi.org/10.1136/bcr-2014-204507

  • Edwards L (2010) Pigmented vulvar lesions. Dermatol Ther 23:449–457

    Article  PubMed  Google Scholar 

  • Egan CA, Zone JJ (1999) Linear IgA bullous dermatosis. Int J Dermatol 38:818–827

    Article  PubMed  CAS  Google Scholar 

  • Elas D, Swick B, Stone MS, Miller M, Stockdale C (2014) Botryomycosis of the vulva: a case report. J Lower Gen Tract Dis 18:e80–e83

    Article  Google Scholar 

  • El-Khoury J, Renald M, Plantier F, Avril M, Moyal-Barracco M (2016) Vulvar hidradenoma papilliferum is located on the sites of mammary-like anogenital glands (MLAGs): analysis of the photographs of 52 tumors. J Am Acad Dermatol 75:380–384

    Article  PubMed  Google Scholar 

  • Farahnik B, Blattner CM, Mortazie MB, Perry BM, Lear W, Elston DM (2017) Interentional treatments for Hailey-Hailey disease. J Am Acad Dermatol 76:551–558

    Article  PubMed  Google Scholar 

  • Fatahzadeh M, Schwartz RA (2007) Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol 57:737–763

    Article  PubMed  Google Scholar 

  • Fistarol SK, Itin PH (2013) Diagnosis and treatment of lichen sclerosus. Am J Clin Dermatol 14:27–47

    Article  PubMed  Google Scholar 

  • Fite C, Plantier F, Dupin N, Avril M, Moyal-Barracco M (2011) Vulvar verruciform xanthoma: ten cases associated with lichen sclerosus, lichen planus, or other conditions. Arch Dermatol 147:1087–1092

    Article  PubMed  Google Scholar 

  • Flagg EW, Schwartz R, Weinstock H (2013) Prevalence of anogenital warts among participants in private health plans in the United States, 2003-2010: potential impact of human papillomavirus vaccination. Am J Pub Health 103:1428–1435

    Article  Google Scholar 

  • Foote CA, Brady SP, Brady KL, Clark NS, Mercurio MG (2013) Vulvar dermatitis from allergy to moist flushable wipes. J Lower Gen Tract Dis 18:E16–E18

    Article  Google Scholar 

  • Fox H, Wells M, Harris M, McWilliam LJ, Anderson GS (1988) Enteric tumours of the lower female genital tract: a report of three cases. Histopathol 12:167–176

    Article  CAS  Google Scholar 

  • Frankel MA, Rhodes HE, Euscher ED (2011) Verruciform xanthoma in an adolescent: a case report. J Lower Gen Tract Dis 16:70–74

    Article  Google Scholar 

  • French P, Ison CA, Macdonald N (2005) Lymphogranuloma venereum in the United Kingdom. Sex Transm Infect 81:97–98

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Garland SM, Steben M, Sings HL, James M, Lu S, Railkar R, Barr E, Haupt RM, Joura EA (2009) Natural history of genital warts: analysis of the placebo arm of 2 randomized phase III trials of a quadrivalent human papillomavirus (types 6,11,16, and 18) vaccine. J Infect Dis 199:805–814

    Article  PubMed  Google Scholar 

  • Ghosh D, Woodrow S, Mathew J, Lopes A, Das N (2011) Chronic granulomatous inflammation of the vulva: an unusual presentation with diagnostic and therapeutic difficulties. J Lower Gen Tract Dis 15:322–324

    Article  Google Scholar 

  • Gilbey S, Moore D, Look K, Sutton G (1997) Vulvar keratoacanthoma. Obstet Gynecol 89:848–850

    Article  CAS  PubMed  Google Scholar 

  • Gleason BC, Hirsch MS, Nucci MR, Schmidt BA, Zembowicz A, Mihm MC, McKee PH, Brenn T (2008) Atypical genital nevi: a clinicopathologic analysis of 56 cases. Am J Surg Pathol 32:51–57

    Article  PubMed  Google Scholar 

  • Goldstein AT, Marinoff SC, Chrostopher K, Srodon M (2005) Prevalence of vulvar lichen sclerosus in a general gynecology practice. J Reprod Med 50:477–480

    PubMed  Google Scholar 

  • Goldstein AT, Metz A (2005) Vulvar Lichen planus. Clin Obstet Gynecol 48:818–823

    Article  PubMed  Google Scholar 

  • Gomes do Amaral RL, Giraldo PC, Cursino K, Goncalves AK, Eleuterio J, Giraldo H (2009) Nodular vulvar herpes in an HIV-positive woman. Int J Obstet Gynecol 107:255

    Article  Google Scholar 

  • Gupta R, Warren T, Wald A (2007) Genital herpes. Lancet 370:2127–2137

    Article  PubMed  Google Scholar 

  • Gurumurthy M, Cairns M, Cruickshank M (2009) Case series of zoon vulvitis. J Lower Gen Tract Dis 14:56–58

    Article  Google Scholar 

  • Gushi A, Kanekura T, Kanzaki T, Eizuru Y (2003) Detection and sequences of human papillomavirus DNA in non-genital seborrheic keratosis of immunocompetent individuals. J Derm Sci 31:143–149

    Article  CAS  Google Scholar 

  • Halvorsen JA, Brevig T, Aas T, Skar AG, Slevolden EM, Moi H (2006) Genital ulcers as initial manifestation of Epstein-Barr virus infection: two new cases and a review of the literature. Acta Derm Venerol 86:439–442

    Article  PubMed  Google Scholar 

  • Heller DS, Bean S (2014) Lesions of the Bartholin gland: a review. J Lower Gen Tract Dis 18:351–357

    Article  Google Scholar 

  • Heller DS (2015) Benign tumors and tumor-like lesions of the vulva. Clin Obstet Gynecol 58:526–535

    Article  PubMed  Google Scholar 

  • Heller J, Roche N, Hameed M (2009) Trichoepithelioma of the vulva: report of a case and review of the literature. J Lower Gen Tract Dis 13:186–187

    Article  Google Scholar 

  • Hoang MP, Reuter J, Papalas JA, Edwards L, Selim MA (2014) Vulvar inflammatory dermatoses: an update and review. Am J Dermatopathol 36:689–704

    Article  PubMed  Google Scholar 

  • Hoang MP, Sangueza OP (2015) Vascular lesions of the vulva. In: Huang MP, Selim MA (eds) Vulvar pathology. Springer, New York, pp 411–438

    Google Scholar 

  • Hoang MP, Fernandez-Figueras MT, Mihm M (2015a) Blistering disorders and acantholytic processes affecting the epidermis of the vulva. In: Huang MP, Selim MA (eds) Vulvar pathology. Springer, New York, pp 71–94

    Google Scholar 

  • Hoang MP, Kazakov DV (2015) Lesions of Anogenital mammary-like glands, adnexal neoplasms and metastases. In: Huang MP, Selim MA (eds) Vulvar pathology. Springer, New York, pp 327–354

    Google Scholar 

  • Hoang MP, Kazakov DV, Selim MA (2015b) Cysts, glandular lesions and others. In: Huang MP, Selim MA (eds) Vulvar pathology. Springer, New York, pp 355–383

    Google Scholar 

  • Hofstetter S, Shah M (2015) Vulvodynia. In: Clin Obstet Gynecol 58–536-545

    Google Scholar 

  • Hope-Rapp E, Anyfantakis V, Fouere S, Bonhomme P, Louison JB, Tandeau de Marsac T, Chaine B, Vallee P, Casin I, Scieux C, Lassau F, Janier M (2010) Etiology of genital ulcer disease. A prospective study of 278 cases seen in an STD clinic in Paris. Sex Transm Dis 37:153–158

    Article  PubMed  Google Scholar 

  • Horn L, Bauerfeind UK, Straub H, Karbe I (2014) Vulval intestinal enteric heteropia with a 10-year follow-up: a case report and review of the literature. Int J Gynecol Pathol 33:258–262

    Article  PubMed  Google Scholar 

  • Hornor G (2004) Ano-genital warts in children: sexual abuse or not? J Pediatr Health Care 18:165–170

    Article  PubMed  Google Scholar 

  • Hoy T, Singhal PK, Willey VJ, Insinga RP (2009) Assessing incidence and economic burden of genital warts with data from a US commercially insured population. Curr Med Res Opin 25:2343–2351

    Article  PubMed  Google Scholar 

  • Huppert JS, Gerber MA, Dietch HR, Mortensen JE, Staat MA, Adams HPJ (2006) Vulvar ulcers in young females: a manifestation of apthosis. J Pediatr Adolesc Gynecol 19:195–204

    Article  PubMed  Google Scholar 

  • Jayasinghe Y, Garland SM (2006) Genital warts in children: what do they mean? Arch Dis Child 91:696–700

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Karaa A, Khachemoune A (2007) Keratoacanthoma: a tumor in search of a classification. Int J Derm 46:671–678

    Article  PubMed  Google Scholar 

  • Kasperkiewicz M, Zillikens D, Schmidt E (2012) Pemphigoid diseases: pathogenesis, diagnosis and treatment. Autoimmunity 45:55–70

    Article  CAS  PubMed  Google Scholar 

  • Kaufman RH (1994) Benign diseases of the vulva and vagina, 4th edn. Mosby, St. Louis

    Google Scholar 

  • Kavala M, Demir FT, Zindanci I, Can B, Turkoglu Z, Zemheri E, Cam OH, Teksen A (2015) Genital involvement in pemphigus vulgaris (PV): correlation with clinical and cervicovaginal pap smear findings. J Am Acad Dermatol 73:655–659

    Article  PubMed  Google Scholar 

  • Kazakov DV, Curik R, Vanecek T, Mukensnabl P, Michal M (2007) Nodular hyperplasia of the Bartholin gland: a clinicopathological study of two cases, including detection of clonality by HUMARA. Am J Dermatopathol 29:385–387

    Article  PubMed  Google Scholar 

  • Kazakov DV, Bouda J, Kacerovska D, Michal M (2010a) Vulvar syringomas with deep extension: a potential histopathologic mimic of microcystic adnexal carcinoma. Int J Gynecol Pathol 30:92–94

    Article  Google Scholar 

  • Kazakov DV, Stewart CJR, Kacerovska D, leake R, Kreuzberg B, Chudacek Z, Hora M, Michal M (2010b) Prostatic-type tissue in the lower female genital tract: a morphologic spectrum including vaginal tubulosquamous polyp, adenomyomatous hyperplasia of paraurethral skene glands (female prostate) and ectopic lesion in the vulva. Am J Surg Pathol 34:950–955

    Article  PubMed  Google Scholar 

  • Kazakov DV, Spagnolo DV, Kacerovska D, Michal M (2011) Lesions of anogenital mammary-like glands: an update. Adv Anat Pathol 18:1–28

    Article  PubMed  Google Scholar 

  • Kelly P, McBride HA, Kennedy K, Connolly LE, McCluggage WG (2011) Misplaced Skene’s glands: glandular elements in the lower female genital tract that are variably immunoreactive with prostate markers and that encompass vaginal tubulosquamos polyp and cervical ectopic prostatic tissue. Int J Gynecol Pathol 30:605–612

    Article  PubMed  Google Scholar 

  • Klein PA, Callen JP (2000) Drug-induced linear IgA bullous dermatosis after vancomycin discontinuance in a patient with renal insufficiency. J Am Acad Dermatol 42(Pt 2):316–323

    Article  CAS  PubMed  Google Scholar 

  • Kneisel A, Hertl M (2011) Autoimmune bullous skin diseases. Part 1: clinical manifestations. JDDG 9:844–857

    PubMed  Google Scholar 

  • Konstantinova AM, Michal M, Kacerovska D, Spagnolo D, Stewart C, Kutzner H, Zelger B, Plaza J, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Scurry J, van der Putte SC, Pyman J, Chetty N, Szabo R (2009) Mammary-like gland adenoma of the vulva: review of 46 cases. Pathology 41:372–378

    Article  Google Scholar 

  • Konstantinova AM, Michal M, Kacerovska D, Spagnolo DV, Stewart CJ, Kutzner H, Zelger B, Plaza JA, Denisjuk N, Hejda V, Shelekhova K, Bisceglia M, Danis D, Zamecnik M, Kerl K, Guenova E, Kazakov D (2016) Hidradenoma papilliferum: a clinicopathologic study of 264 tumors from 261 patients, with emphasis on mammary-type alterations. Am J Dermatopathol 38:374–383

    Article  PubMed  Google Scholar 

  • Konstantinova AM, Kyrpychova L, Belousva IE, Spagnolo DV, Kacerovska D, Michal M, Kerl K, Kazakov DV (2017a) Anogenital mammary-like glands: a study of their normal histology with emphasis on glandular depth, presence of columnar epithelial cells, and distribution of elastic fibers. Am J Dermatopathol 39:663–67

    Google Scholar 

  • Konstantinova AM, Stewart CJR, Kyrpychova L, Belousva IE, Michal M, Kazakov DV (2017b) An immunohistochemical study of anogenital mammary-like glands. Am J Dermatopathol 39:599–605

    Google Scholar 

  • Koo YJ, Kim YS, Min KJ, Hong JH, Lee JK (2016) High -risk human papillomavirus infection and the prediction of poor treatment response and disease recurrence in patients with vulvovaginal condyloma. Int J Gynecol Obstet 132:20–24

    Article  Google Scholar 

  • Koranantakul O, Lekhakula A, Wansit R, Koranantakul Y (1991) Cutaneous myiasis of vulva caused by the muscoid fly (Chrysomyia genus). Southeast Asian J Trop Med Public Health 22:458–460

    CAS  PubMed  Google Scholar 

  • Kuniyuki S, Fukushima Y, Yoshida Y, Yamanaka K, Maekawa N, Inoue T (2008) Ciliated cyst of the vulva: oestrogen and progesterone receptors. Acta Derm Venereol 88:514–515

    Article  PubMed  Google Scholar 

  • Kurashige Y, Kishida K, Kurashige K, Minemura T, Nagatani T (2014) Hidradenoma papilliferum of the vulva in association with an anogenital mammary-like gland. J Dermatol 41:411–413

    Article  PubMed  Google Scholar 

  • Lacey CJN, Woodhall SC, Wikstrom A, Ross J (2013) 2012 European guideline for the management of anogenital warts. J Europ Acad Dermatol Vener 27:e263–e270

    Article  CAS  Google Scholar 

  • Lawrance NJ, Mowatt D, Yell JA (2015) Massive localized vulval lymphedema with lymphangiomas of the labia majora, misdiagnosed as viral warts. J Lower Gen Tract Dis 19:e64–e65

    Article  Google Scholar 

  • Leclair CM, Goetsch MF, Korcheva VB, Anderson R, Peters D, Morgan TK (2011) Differences in primary compared with secondary vestibulodynia by immunohistochemistry. Obstet Gynecol 117:1307–1313

    Article  PubMed Central  PubMed  Google Scholar 

  • Lee MY, Dalpiaz A, Schwamb R, Miao Y, Waltzer W, Khan A (2014) Clinical pathology of Bartholin’s glands: a review of the literature. Curr Urol 8:22–25

    Article  Google Scholar 

  • Lewis FM (1998) Vulval lichen planus. British J Dermatol 138:569–575

    Google Scholar 

  • Li J, Ackerman AB (1994) Seborrheic keratoses that contain human papillomavirus are condyloma acuminata. Am J Dermatopathol 16:398–405

    Article  CAS  PubMed  Google Scholar 

  • Li J, Shi Y, Zhou C, Lin J (2015) Diagnosis and treatment of perineal endometriosis: review of 17 cases. Arch Gynecol Obstet 292:1295–1299

    Article  PubMed  Google Scholar 

  • Lora V, Scarabello A, Cota C (2015) Warty dyskeratoma as a cutaneous horn on the Mons pubis. Am J Dermatopathol 37:801–804

    Article  Google Scholar 

  • Lynch PJ, Moyal-Barracco M, Bogliatto F, Micheletti L, Scurry J (2006) ISSVD classification of vulvar dermatoses: pathologic subsets and their clinical correlates. J Reprod Med 2007:3–9

    Google Scholar 

  • Lyrio LDC, Grassi MFR, Santana IU, Olavarria VG, Gomes A, Costa Pinto L, Oliveira RP, Aquino R, Santiago MB (2013) Prevalence of human papillomavirus infection in women with systemic lupus erythematosus. Rheumatol Int 33:335–340

    Article  CAS  PubMed  Google Scholar 

  • Maniar KP, Ronnett BM, Vang R, Yemelyanova A (2013) Coexisting high-grade vulvar intraepithelial neoplasia (VIN) and condyloma acuminatum-independent lesions due to different HPV types occurring in immunocompromised patients. Am J Surg Pathol 37:53–60

    Article  PubMed Central  PubMed  Google Scholar 

  • Manoj K, Soma M, Ajay L, Ashish A, Rakesh S, Paliwal RV (2008) Tubercular sinus of labia majora: rare case report. Infect Dis Obstet Gynecol 2008:81753. https://doi.org/10.1155/2008/87515

    Article  Google Scholar 

  • Margesson LJ (2006) Vulvar disease pearls. Dermatol Clin 24:145–155

    Article  CAS  PubMed  Google Scholar 

  • Marquette GP, Su B, Woodruff JD (1985) Introital adenosis associated with Stevens-Johnson syndrome. Obstet Gynecol 66:143–145

    CAS  PubMed  Google Scholar 

  • Marwah S, Bergman ML (1980) Ectopic salivary gland in the vulva (choristoma): report of a case and review of the literature. Obstet Gynecol 56:389–391

    CAS  PubMed  Google Scholar 

  • Marzano DA, Haefner HK (2004) The Bartholin gland cyst: past, present and future. J Lower Gen Tract Dis 8:195–204

    Article  Google Scholar 

  • Marzano A, Ramoni S, Caputo R (2008) Amicrobial pustulosis of the folds: report of 6 cases and a literature review. Dermatology 216:305–311

    Article  PubMed  Google Scholar 

  • Mat C, Yurdakul S, Sevim A, Ozyazgan Y, Tuzun Y (2013) Behcet’s syndrome: facts and controversies. Clin Dermatol 31:352–361

    Article  PubMed  Google Scholar 

  • Medeiros F, Nascimento AF, Crum CP (2005) Early vulvar squamous neoplasia: advances in classification, diagnosis and differential diagnosis. Adv Anat Pathol 12:20–26

    Article  PubMed  Google Scholar 

  • Mittal P, Prakash V, Gupta R, Dewan R, Singhal S, Suri J (2013) Giant condyloma acuminatum of vulva treated by surgical excision and reconstruction of defect. Arch Gynecol Obstet 287:1047–1048

    Article  PubMed  Google Scholar 

  • Miziara ID, Mahmoud A, chagury AA, Alves RD (2013) Bullous systemic lupus erythematosus: case report. Int Arch Otorhinolayngol 17:344–346

    Article  Google Scholar 

  • Mohammed TT, Olumide YM (2008) Chancroid and human immunodeficiency virus infection-a review. Int J Dermatol 47:1–8

    Article  PubMed  Google Scholar 

  • Mosunjac M, Park JP, Wang YF, Tadros T, Siddiqui M, Bagirov M, Little J (2009) Genital and perianal herpes simplex simulating neoplasia in patients with AIDS. AIDS Patient Care STDs 23. https://doi.org/10.1089/apc.2008.0143

  • Moyal-Barracco M, Wendling J (2014) Vulvar dermatosis. Best Prac Res Clin Obstet Gynecol 28:946–958

    Article  Google Scholar 

  • Murzaku EK, Penn LA, Hale CS, Pomeranz MK, Polsky D (2014) Vulvar nevi, melanosis, and melanoma: an epidemiologic, clinical and histopathologic review. J Am Acad Dermatol 71:1241–1249

    Article  PubMed  Google Scholar 

  • Nakayama J, Busse R (2010) An analysis of vulvar necrotizing fasciitis in the unique and ethnically diverse Hawaiian population. Hawaii Med J 69:13-16

    Google Scholar 

  • Nascimento M, Cominos D, Davies N, Obermair A (2005) Vulval keratoacanthoma. Gyn Onc 97:674–676

    Article  Google Scholar 

  • Nasu K, Okamato M, Nishida M, Narahara H (2013) Endometriosis of the perineum. Obstet Gynaecol Res 39:1095–1097

    Article  Google Scholar 

  • Nettina SM (1998) Herpes genitalis. Lippincotts Prim Care Pract 2:303–306

    CAS  PubMed  Google Scholar 

  • Newland JR, Fusaro RM (1991) Mucinous cysts of the vulva. Nebr Med J 76:307–310

    CAS  PubMed  Google Scholar 

  • Nigam JS, Deshpande AH, Bharti JN, Nair V (2017) Melanocytic colonization of Bartholin cyst: a rarely observed phenomenon. J Lower Gen Tract Dis 21:1–2

    Article  Google Scholar 

  • Nomelini RS, Pansani PL, Guimaraes PDN, Martins-Filho A, Barcelos ACM, Murta EFC (2010) Vulvar angiokeratoma. J Obstet Gynaecol 30:418–419

    Article  CAS  PubMed  Google Scholar 

  • O'Farrell N, Moi H (2016) 2016 European guideline on donovanosis. Int J STD AIDS 27:605–607

    Article  PubMed  Google Scholar 

  • O'Gorman SM, Torgerson RR (2013) Allergic contact dermatitis of the vulva. Dermatitis 24:64–72

    Article  CAS  PubMed  Google Scholar 

  • Oliveira A, Lobo I, Selores M (2011) Asymptomatic vulvar pigmentation. Clin Exp Dermatol 36:921–922

    Article  CAS  PubMed  Google Scholar 

  • Osarumwense DO (2010) Post genital mutilation giant clitoral epidermoid inclusion cyst in Benin City. Nigeria J Pediatr Adolesc Gynecol 23:336–340

    Article  Google Scholar 

  • Ozcan F, Bilgic R, Cesur S (2006) Vulvar keratoacanthoma. APMIS 114:562–565

    Article  Google Scholar 

  • Ozcan Z (2009) Multiple eccrine hidrocystomas of the vulva. Int J Gynaecol Obstet 1:65

    Article  Google Scholar 

  • Paulus YM, Wong AE, Chen B, Jacobson MT (2010) Preputial epidermoid cyst: an atypical case of acquired pseudoclitoromegaly. J Lower Gen Tract Dis 14:382–386

    Article  Google Scholar 

  • Pereira IB, Khan A (2017) Sarcoidosis rare cutaneous manifestations: vulval and perianal involvement. J Obstet Gynaecol 37:539–540

    Article  PubMed  Google Scholar 

  • Pernet C, Bessis D, Savagnac M, Tron E, Guillot B, Hovnanian A (2012) Genitoperineal papular acantholytic dyskeratosis is allelic to Hailey-Hailey disease. Brit J Dermatol 167:211–213

    Article  Google Scholar 

  • Prayson RA, Stoler MH, Hart WR (1995) Vulvar vestibulitis. A histopathologic study of 36 cases, including human papillomavirus in situ hybridization analysis. Am J Surg Path 19:154–160

    Article  CAS  PubMed  Google Scholar 

  • Quddus MR, Sung CJ, Simon RA, Lawrence WD (2014) Localized amyloidosis of the vulva with and without vulvar intraepithelial neoplasia: report of a series. Hum Path 45:2037–2042

    Article  CAS  PubMed  Google Scholar 

  • Read TR, Hocking JS, Chen MY (2011) The near disappearance of genital warts in young women 4 years after commencing a national human papillomavirus (HPV) vaccination program. Sex Transm Infect 87:544–547

    Article  PubMed  Google Scholar 

  • Reed BG, Shippey S, Kremp A, Belin E (2013) Vulvar pyoderma gangrenosum originating from a healed obstetric laceration. Obstet Gynecol 122:452–454

    Article  PubMed  Google Scholar 

  • Regauer S, Eberz B, Beham-Schmid C (2015) Mast cell infiltrates in vulvodynia represent secondary and idiopathic mast cell hyperplasia. APMIS 123:452–445

    Article  CAS  PubMed  Google Scholar 

  • Ridley CM, Neill SM (1999) The vulva, 2nd edn. Blackwell, Oxford, pp 1–36

    Google Scholar 

  • Ribe A (2008) Melanocytic lesions of the genital area with attention given to atypical genital nevi. J Cutan Pathol 35:24–27

    Article  PubMed  Google Scholar 

  • Riszk DEE, Mohammed KH, Joshi SU, Al-Shabani AY, Bossmar TR (2007) A large clitoral epidermoid inclusion cyst Forst presenting in adulthood following childhood circumcision. J Obstetr Gynecol 27:446–448

    Article  Google Scholar 

  • Robinson JB, Im DD, Simmons-O’Brien E, Rosenshein NB (1998) Etretinate: therapy for plasma cell vulvitis. Obstet Gynecol 51:347–351

    Google Scholar 

  • Rock B, Hood AF, Rock JA (1990) Prospective study of vulvar nevi. J Am Acad Dermatol 22:104–106

    Article  CAS  PubMed  Google Scholar 

  • Ruocca V, Ruocco E, Schivao AL, Brunetti G, Guerrera LP, Wolf R (2013) Pemphigus: etiology, pathogenesis, and inducing or triggering factors: facts and controversies. Clin Dermatol 31(374):381

    Google Scholar 

  • Ruocco E, Wolf R, Ruocco V, Brunetti G, Romano F, Schiavo AL (2013a) Pemphigus: associations and management guidelines: facts and controversies. Clin Dermatol 31:382–390

    Article  PubMed  Google Scholar 

  • Ruocco E, Wolf R, Cacavale S, Brancaccio G, Ruocco V, Schiavo AL (2013b) Bullous pemphigoid: associations and management guidelines: facts and controversies. Clin Dermatol 31:400–412

    Article  PubMed  Google Scholar 

  • Ruocco V, Ruocco E, Caccavale S, Gambardella A, Schivao AL (2015) Pemphigus vegetans of the folds (intertriginous areas). Clin Dermatol 33:471–476

    Article  PubMed  Google Scholar 

  • Satoh M, Yamamoto T (2013) Genital pyoderma gangrenosusm: report of two cases and published work review of Japanese cases. J Dermatol 40:840–843

    PubMed  Google Scholar 

  • Saitoh A, Ohya T, Yoshida S, Hosoya R, Nishimura K (1995) A case report of Stevens-Johnson syndrome with mycoplasma infection. Acta Paediatr Jpn 37:113–115

    Article  CAS  PubMed  Google Scholar 

  • Sand FL, Thomsen SF (2017) Skin diseases of the vulva: infectious diseases. J Obstet Gynaecol. https://doi.org/10.1080/01443615.2017.1306696

  • Sangueza JM, Saenz ML (2007) Challenge. Am J Dermatopathol 29:210

    Article  PubMed  Google Scholar 

  • Santana IU, Gomes A, Lyrio LDC, Grassi MFR, Santiago MB (2011) Systemic lupus erythematosus, human papillomavirus infection, cervical pre-malignant and malignant lesions: a systematic review. Clin Rheumatol 30:665–672

    Article  PubMed  Google Scholar 

  • Sbano P, Rubegni P, Risulo M, De Nisi MC, Fimiani M (2007) A case of idiopathic granulomatous cheilitis and vulvitis. Int J Dermatol 46:720–721

    Article  PubMed  Google Scholar 

  • Schiavo AL, Ruocco E, Brancaccio G, Caccavale S, Ruocco V, Wolf R (2013) Bullous pemphigoid: etiology, pathogenesis and inducing factors: facts and controversies. Clinics in Dermatol 31:391–399

    Article  Google Scholar 

  • Schneider CA, Festa S, Spillert CR, Bruce CJ, Lazaro EJ (1994) Hydrocele of the canal of Nuck. N J Med 91:37–38

    CAS  PubMed  Google Scholar 

  • Schneider M, Cardones A, Selim MA (2016) Amicrobial pustulosis of the folds and autoimmunity. J Lower Gen Tract Dis 20:e57–e58

    Article  Google Scholar 

  • Schober MS, Hendrickson BW, Alpert SA (2014) Spontaneous clitoral hood epidermal inclusion cyst mimicking clitoromegaly in a pediatric patient. Urology 84:206–208

    Article  PubMed  Google Scholar 

  • Schofield JK, Tatnall FM, Leigh IM (1993) Recurrent erythema multiforme: clinical features and treatment in a large series of patients. Brit J Dermatol 128:542–545

    Article  CAS  Google Scholar 

  • Schwartz R (2004) Keratoacanthoma: a clinico-pathologic enigma. Dermatol Surg 30:326–333

    PubMed  Google Scholar 

  • Scurry J, van der Putte SCJ, Pyman J, Chetty N, Szabo R (2009) Mammary-like gland adenoma of the vulva: a review of 46 cases. Pathology 41:372–378

    Article  PubMed  Google Scholar 

  • Selim MA et al (2015) Infectious diseases and infestations of the vulva. In: Hoang MP, Selim MA (eds) Vulvar pathology. Springer, New York, pp 139–193

    Google Scholar 

  • Shen HP, Chang WC, Hsieh CH, Yang TC, Hung YC (2011) Vulvar tuberculosis. Taiwan J Obstet Gynecol 50:106–108

    Article  PubMed  Google Scholar 

  • Sherman V, McPherson T, Baldo M, Salim A, Gao XH, Wojnarowska F (2010) The high rate of familial lichen sclerosus suggests a genetic contribution: an observational cohort study. J Eur Acad Dermatol Venereol 24:1031–1034

    PubMed  CAS  Google Scholar 

  • Simpson RC, Thomas KS, Leighton P, Murphy R (2013) Diagnostic criteria for erosive lichen planus affecting the vulva: an international electronic-Delphi consensus exercise. Brit J Dermatol 169:337–343

    Article  CAS  Google Scholar 

  • Sington J, Chandrapala R, Manek S, Hollowood K (2006) Mitotic count is not predictive of clinical behavior in hidradenoma papilliferum of the vulva: a clinicopathologic study of 19 cases. Am J Dermatopathol 28:322–326

    Article  PubMed  Google Scholar 

  • Stefanaki C, Barkas G, Valari M, Bethimoutis G, Nicolaidou E, Vosynioti V, Kontochristopoulos G, Papadogeorgaki H, Verra P, Katsarou A (2012) Condyloma acuminata in children. Pediatr Infect Dis J 31:422–424

    Article  PubMed  Google Scholar 

  • Stephenson H, Dotters DJ, Katz V, Droegemueller W (1992) Necrotizing fasciitis of the vulva. Am J Obstet Gynecol 166:1324–1327

    Article  CAS  PubMed  Google Scholar 

  • Steshenko O, Chandrasekaran N, Lawton F (2014) Syringocystadenoma papilliferum of the vulva: a rarity in gynaecology. BMJ Case Reports. https://doi.org/10.1135/bcr-2014-203902

  • Strehl JD, Mehlhorn G, Koch MC, Harrer EG, Harrer T, Beckmann MW, Agaimy A (2012) Int J Gynecol Pathol 31:286–293

    Article  PubMed  Google Scholar 

  • Sultan HY, Boyle AA, Sheppard N (2012) Necrotising fasciitis. BMJ 345:e4274. https://doi.org/10.1136/bmj.e4274

    Article  PubMed  Google Scholar 

  • Sun T, Schwartz NS, Sewell C, Lieberman P, Gross S (1991) Enterobius egg granuloma of the vulva and peritoneum: review of the literature. Am J Trop Med Hyg 45:249–253

    Article  CAS  PubMed  Google Scholar 

  • Tangjitgamol S, Loharamtaweethong K, Thawaramara T, Chanpanitkitchot S (2013) Vulvar pseudoepitheliomatous hyperplasia mimicking cancer in an immunocompromised patient. J Obstet Gynecol Res 40:255–258

    Article  Google Scholar 

  • Takagi A, Kamijo M, Ikeda S (2016) Darier Disease. J Dermatol 43:275–279

    Article  CAS  PubMed  Google Scholar 

  • Taylor S, Drake SM, Dedicoat M, Wood MJ (1998) Genital ulcers associated with acute Epstein-Barr virus infection. Sex Transm Infect 74:296–297

    Article  PubMed Central  PubMed  CAS  Google Scholar 

  • Tomazzini E, Giraldo P, Amaral R, Eleuterio J, Cintra ML, Giraldo HPD (2008) Vulvar calcinosis in childhood. Int J Gynaecol Obstet 103:263–264

    Article  PubMed  Google Scholar 

  • Tommola P, Butzow R, Unkila-Kallio L, Paavonen J, Meri S (2015) Activation of vestibule-associated lymphoid tissue in localized provoked vulvodynia. Am J Obstet Gynecol 212:476.e1–476.e8

    Article  Google Scholar 

  • Van der Avoort IAM, van der Laak JAWM, Otte-Holler I, van de Nieuwenhof HP, Massuger LFAG, de Hullu J, van Kempen LCLT (2010) The prognostic value of blood and lymph vessel parameters in lichen sclerosus for vulvar squamous cell carcinoma development: an immunohistochemical study. Am J Obstet Gynecol 203-167:e1–e8

    Google Scholar 

  • Van der Putte SC (1991) Anogenital "sweat" glands. Histology and pathology of a gland the may mimic mammary glands. Am J Dermatopathol 13:557–567

    Article  PubMed  Google Scholar 

  • Van der Putte SC (1994) Mammary-like glands of the vulva and their disorders. Int J Gynecol Pathol 13:150–160

    Article  PubMed  Google Scholar 

  • Virgili A, Mantovani L, Lauriola MM, Marzola A, Corazza M (2008) Tacrolimus 0.1% ointment: is it really effective in plasma cell vulvitis? Report of four cases. Dermatology 216:243–246

    Article  CAS  PubMed  Google Scholar 

  • Virgili A, Corazza M, Minghetti S, Borghi A (2015) Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. Dermatology 230:113–118

    Article  PubMed  Google Scholar 

  • Vitrey D, Frachon S, Balme B, Golfier F (2003) Tubulovillous adenoma of the vulva. Obstet Gynecol 102:1160–1163

    CAS  PubMed  Google Scholar 

  • Wang MZ, Camilleri MJ, Guo R, Wieland C (2017) Amicrobial pustulosis of the folds: report of 4 cases. J Cutan Pathol 44:367–372

    Article  PubMed  Google Scholar 

  • Wakashin K (2007) Sanitary napkin contact dermatitis of the vulva: location dependent differences in skin surface conditions may play a role in negative patch test results. J Dermatol 34:834–837

    Article  PubMed  Google Scholar 

  • Weedon D, Malo J, Brooks D, Williamson R (2010) Keratoacanthoma: is it really a variant of squamous carcinoma? ANZ J Surg 80:129–130

    Article  PubMed  Google Scholar 

  • Wieselthier JS, Pincus SH (1993) Hailey-Hailey disease of the vulva. Arch Dermatol 129:1344–1345

    Article  CAS  PubMed  Google Scholar 

  • Weyers W (2013) Hypertrophic lichen sclerosus with dyskeratosis and parakeratosis- a common presentation of vulvar lichen sclerosus not associated with a significant risk of malignancy. Am J Dermatopathol 35:713–721

    Article  PubMed  Google Scholar 

  • Weyers W (2015) Hypertrophic lichen sclerosus sine sclerosis: clues to histopathologic diagnosis when presenting as psoriasiform lichenoid dermatitis. J Cutan Pathol 42:118–129

    Article  PubMed  Google Scholar 

  • Wilkinson EJ, Stone IK (2008) Atlas of vulvar disease, 2nd edn. Lippincott Williams & Wilkins, Baltimore

    Google Scholar 

  • Wojnarowska F, Frith P (1997) Linear IgA disease. Dev Ophthalmol 28:64–72

    Article  CAS  PubMed  Google Scholar 

  • Xie Y, Shi L, Xiong X, Wu E, Veasly C, Dade C (2012) Economic burden and quality of life of vulvodynia in the United States. Curr Med Res Opinion 28:601–608

    Article  Google Scholar 

  • Yazici Y, Yurdakul S, Yazici H (2010) Behcet’s Syndrome. Curr Rheumatol Rep 12:429–435

    Article  PubMed  Google Scholar 

  • Yigiter M, Arda IS, Tosum E, Celik M, Hicsonmez A (2008) Angiokeratoma of clitoris: a rare lesion in an adolescent girl. Urology 71:604–606

    Article  PubMed  Google Scholar 

  • Yoganathan S, Bohl TG, Mason G (1994) Plasma cell balanitis and vulvitis (of zoon). A study of 10 cases. J Reprod Med 39:939–944

    CAS  PubMed  Google Scholar 

  • Young M, Aldridge L, Parker P (2017) Psoriasis for the primary care practioner. J Amer Nurse Pract 29:157–178

    Google Scholar 

  • Yu WY, Ng E, Hale C, Hu S, Pomeranz MK (2016) Papular acantholytic dyskeratosis of the vulva associated with familial Hailey-Hailey disease. Clin Exp Dermatol 41:628–631

    Article  CAS  PubMed  Google Scholar 

  • Zaraa I, Sellami A, Bougerra C, Sellami MK, Chelly I, Zitouna M, Makni S, Hmida AB, Mokni M, Osman AB (2010) Pemphigus vegetans: a clinical, histological, immunopathological and prognostic study. J Euro Acad Dermato Venereol 25:1160–1167

    Article  Google Scholar 

  • Zhu J, Lu Z, Zheng M (2014) Acquired progressive lymphangioma in the inguinal area mimicking gioant condyloma acuminatum. Cutis 93:316–319

    PubMed  Google Scholar 

  • Zhuang K, Xu F, Ran Y, Lama J (2015) Atypical infantile genital Molluscum contagiosum. An Bras Dermatol 90:403–405

    Article  PubMed Central  PubMed  Google Scholar 

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Rush, D., Wilkinson, E.J. (2018). Benign Diseases of the Vulva. In: Kurman, R., Hedrick Ellenson, L., Ronnett, B. (eds) Blaustein's Pathology of the Female Genital Tract. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3165-7_1-2

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