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Diphosphonates Mode of Action and Clinical Applications

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Phosphate Metabolism

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 81))

Abstract

This paper will review the current knowledge of the mode of action of diphosphonates on calcium and phosphate metabolism and of the clinical application of these compounds. The relation with inorganic phosphate will be emphasized. In view of the space available no references will be given, the reader being referred to two recent reviews (1,2).

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References

  1. Russell, R.G.G., and Fleisch, H.: Pyrophosphate and diphosphonates in skeletal metabolism. Clin.Orthop. Rel.Res. 108: 241, 1975.

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  2. Fleisch, H., and Russell, R.G.G.: Experimental and clinical studies with pyrophosphate and diphosphonates. In: Calcium Metabolism and Bone in Renal Disease (David, D.S., ed.), John Wiley & Sons Inc., New York, in press.

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Author information

Authors and Affiliations

  1. Department of Pathophysiology, University of Berne, Berne, Switzerland

    H. Fleisch, D. Fast, R. Rizzoli, U. Trechsel & J.-P. Bonjour

Authors
  1. H. Fleisch
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  2. D. Fast
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  3. R. Rizzoli
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  4. U. Trechsel
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  5. J.-P. Bonjour
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Editor information

Editors and Affiliations

  1. University of Southern California, Los Angeles, California, USA

    Shaul G. Massry

  2. Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany

    Eberhard Ritz

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© 1977 Springer Science+Business Media New York

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Fleisch, H., Fast, D., Rizzoli, R., Trechsel, U., Bonjour, JP. (1977). Diphosphonates Mode of Action and Clinical Applications. In: Massry, S.G., Ritz, E. (eds) Phosphate Metabolism. Advances in Experimental Medicine and Biology, vol 81. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-4217-5_27

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  • DOI: https://doi.org/10.1007/978-1-4613-4217-5_27

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-4219-9

  • Online ISBN: 978-1-4613-4217-5

  • eBook Packages: Springer Book Archive

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