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Influence of Ischemia and Infarction on Cardiac Vagal and Sympathetic Innervation

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Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 94))

Abstract

Although the importance of the autonomic nervous system in modulating the genesis of cardiac arrhythmias has been known for many years and is widely accepted, the precise mechanisms by which such modulation results is incompletely understood. Endpoints, after a neural intervention, such as changes in the spontaneous development or electrical induction of arrhythmias, the fibrillation or repetitive response threshold or overall mortality, for example, provide vital information that a neural manipulation exerted an effect on the arrhythmia substrate, but they do not expose the underlying electrophysiologic mechanism. Knowledge of the latter is critical to formulate ways to intervene discretely and uniquely.

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Authors
  1. Douglas P. Zipes
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Editors and Affiliations

  1. Department of Pharmacology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, P&S 7-517, New York, 10032, New York, USA

    Michael R. Rosen M.D. (Professor of Pharmacology and Pediatrics) (Professor of Pharmacology and Pediatrics)

  2. Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, Efron Street, Post Office Box 9697, Haifa, 31096, Israel

    Yoram Palti M.D., Ph.D. (Director) (Director)

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© 1989 Kluwer Academic Publishers, Boston/Dordrecht/London

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Zipes, D.P. (1989). Influence of Ischemia and Infarction on Cardiac Vagal and Sympathetic Innervation. In: Rosen, M.R., Palti, Y. (eds) Lethal Arrhythmias Resulting from Myocardial Ischemia and Infarction. Developments in Cardiovascular Medicine, vol 94. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1649-7_13

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  • DOI: https://doi.org/10.1007/978-1-4613-1649-7_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8916-6

  • Online ISBN: 978-1-4613-1649-7

  • eBook Packages: Springer Book Archive

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