Skip to main content

Rationale for a Conservative Approach and Arguments Against Aggressive Surgical Approaches

  • Chapter
  • First Online:
Controversies in Aortic Dissection and Aneurysmal Disease

Abstract

Type A dissection is one of the few remaining true surgical emergencies. Without surgery, the risk of death is still as high as 50 % at 48 h. Patients must therefore have a repair as early as possible to have a chance of survival. In the last four to five decades, surgeons have gained experience of more complex operations for the aortic root and arch in the elective setting. Encouraged by their success, some have proposed performing the same complex operations in cases of type A dissection. In this chapter we put forward a number of arguments against these aggressive approaches. The fundamental counter-argument is that the emergency dissection patient is quite different from the elective aneurysm patient. In aneurysm cases, the patient arrives in theatre in a stable situation and any malperfusion that may exist has been compensated for. Patients presenting as emergencies with type A aortic dissection are unstable and ill-prepared for the insult of the operation. The accompanying systemic inflammatory response to arterial dissection will be compounded by extra-corporeal circulation and hypothermia if used. The “instantaneous risk to life” imposed by type A aortic dissection immediately follows this tearing though the arterial media and only falls below risks offered by surgery after 14 days. Considering these issues, operations for these patients must be prompt and swift in order to minimise the additional insult of surgery. This chapter summarises the evidence in support of this position.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. DeBakey ME, McCollum CH, Crawford ES, Morris Jr GC, Howell J, Noon GP, et al. Dissection and dissecting aneurysms of the aorta: twenty-year follow-up of five hundred twenty-seven patients treated surgically. Surgery. 1982;92(6):1118–34. PubMed PMID: 7147190.

    CAS  PubMed  Google Scholar 

  2. Sato F, Kitamura T, Kongo M, Okinaka T, Onishi K, Ito M, et al. Newly diagnosed acute aortic dissection: characteristics, treatment modifications, and outcomes. Int Heart J. 2005;46(6):1083–98. PubMed PMID: 16394604.

    Article  PubMed  Google Scholar 

  3. Yun KL, Glower DD, Miller DC, Fann JI, Mitchell RS, White WD, et al. Aortic dissection resulting from tear of transverse arch: is concomitant arch repair warranted? J Thorac Cardiovasc Surg. 1991;102(3):355–68. discussion 68–70 PubMed PMID: 1881176.

    CAS  PubMed  Google Scholar 

  4. Moon MR, Sundt 3rd TM, Pasque MK, Barner HB, Huddleston CB, Damiano Jr RJ, et al. Does the extent of proximal or distal resection influence outcome for type A dissections? Ann Thorac Surg. 2001;71(4):1244–9. discussion 9–50. PubMed PMID: 11308168.

    Article  CAS  PubMed  Google Scholar 

  5. Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The international registry of acute aortic dissection (irad): new insights into an old disease. JAMA J Am Med Assoc. 2000;283(7):897–903. PubMed PMID: 10685714.

    Article  CAS  Google Scholar 

  6. Apaydin AZ, Buket S, Posacioglu H, Islamoglu F, Calkavur T, Yagdi T, et al. Perioperative risk factors for mortality in patients with acute type A aortic dissection. Ann Thorac Surg. 2002;74(6):2034–9; discussion 9. PubMed PMID: 12643392.

    Article  PubMed  Google Scholar 

  7. Gore I, Hirst Jr AE. Dissecting aneurysm of the aorta. Cardiovasc Clin. 1973;5(1):239–60. PubMed PMID: 4589962.

    CAS  PubMed  Google Scholar 

  8. Anagnostopolous CE. Acute aortic dissection. 1975. University Park Press, Baltimore, Md.

    Google Scholar 

  9. Miller DC, Mitchell RS, Oyer PE, Stinson EB, Jamieson SW, Shumway NE. Independent determinants of operative mortality for patients with aortic dissections. Circulation. 1984;70(3 Pt 2):I153–64. PubMed PMID: 6235061.

    CAS  PubMed  Google Scholar 

  10. Fann JI, Smith JA, Miller DC, Mitchell RS, Moore KA, Grunkemeier G, et al. Surgical management of aortic dissection during a 30-year period. Circulation. 1995;92(9 Suppl):II113–21. PubMed PMID: 7586393.

    Article  CAS  PubMed  Google Scholar 

  11. Bick RL, Schmalhorst WR, Arbegast NR. Alterations of hemostasis associated with cardiopulmonary bypass. Thromb Res. 1976;8(3):285–302. PubMed PMID: 131387.

    Article  CAS  PubMed  Google Scholar 

  12. Connolly JE, Roy A, Guernsey JM, Stemmer EA. Bloodless surgery by means of profound hypothermia and circulatory arrest. Effect on brain and heart. Ann Surg. 1965;162(4):724–37. PubMed PMID: 5833592. Pubmed Central PMCID: 1476969.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  13. Donald DE, Fellows JL. Relation of temperature, gas tension and hydrostatic pressure to the formation of gas bubbles in extracorporeally oxygenated blood. Surg Forum. 1960;10:589–92. PubMed PMID: 13817460.

    CAS  PubMed  Google Scholar 

  14. Miller DR, Hallaba MA, Steegmann AT. Effect of profound hypothermia with circulatory arrest in dogs: special reference to changes in cerebrovascular permeability. Ann Surg. 1965;161:272–85. PubMed PMID: 14260027. Pubmed Central PMCID: 1408925.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. Shiiya N, Matsuzaki K, Kunihara T, Murashita T, Matsui Y. Management of vital organ malperfusion in acute aortic dissection: proposal of a mechanism-specific approach. Gen Thorac Cardiovasc Surg. 2007;55(3):85–90. PubMed PMID: 17447505.

    Article  PubMed  Google Scholar 

  16. Fann JI, Sarris GE, Mitchell RS, Shumway NE, Stinson EB, Oyer PE, et al. Treatment of patients with aortic dissection presenting with peripheral vascular complications. Ann Surg. 1990;212(6):705–13. PubMed PMID: 2256762. Pubmed Central PMCID: 1358256.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  17. Girdauskas E, Kuntze T, Borger MA, Falk V, Mohr FW. Surgical risk of preoperative malperfusion in acute type A aortic dissection. J Thorac Cardiovasc Surg. 2009;138(6):1363–9. PubMed PMID: 19733865.

    Article  PubMed  Google Scholar 

  18. Yagdi T, Atay Y, Engin C, Mahmudov R, Tetik O, Iyem H, et al. Impact of organ malperfusion on mortality and morbidity in acute type A aortic dissections. J Card Surg. 2006;21(4):363–9. PubMed PMID: 16846414.

    Article  PubMed  Google Scholar 

  19. Fann JI, Sarris GE, Miller DC, Mitchell RS, Oyer PE, Stinson EB, et al. Surgical management of acute aortic dissection complicated by stroke. Circulation. 1989;80(3 Pt 1):I257–63. PubMed PMID: 2766534.

    CAS  PubMed  Google Scholar 

  20. Alvarez J, Matias-Guiu J, Sumalla J, Molins M, Insa R, Molto JM, et al. Ischemic stroke in young adults. I. Analysis of the etiological subgroups. Acta Neurol Scand. 1989;80(1):28–34. PubMed PMID: 2782039.

    Article  CAS  PubMed  Google Scholar 

  21. Gaul C, Dietrich W, Erbguth FJ. Neurological symptoms in aortic dissection: a challenge for neurologists. Cerebrovasc Dis. 2008;26(1):1–8. PubMed PMID: 18511865.

    Article  PubMed  Google Scholar 

  22. Chase TN, Rosman NP, Price DL. The cerebral syndromes associated with dissecting aneurysm of the aorta. A clinicopathological study. Brain J Neurol. 1968;91(1):173–90. PubMed PMID: 5643281.

    Article  CAS  Google Scholar 

  23. Morimoto N, Okada K, Okita Y. Lack of neurologic improvement after aortic repair for acute type A aortic dissection complicated by cerebral malperfusion: predictors and association with survival. J Thorac Cardiovasc Surg. 2011;142(6):1540–4. PubMed PMID: 21664623.

    Article  PubMed  Google Scholar 

  24. Tanaka H, Okada K, Yamashita T, Morimoto Y, Kawanishi Y, Okita Y. Surgical results of acute aortic dissection complicated with cerebral malperfusion. Ann Thorac Surg. 2005;80(1):72–6. PubMed PMID: 15975343.

    Article  PubMed  Google Scholar 

  25. Estrera AL, Garami Z, Miller CC, Porat EE, Achouh PE, Dhareshwar J, et al. Acute type A aortic dissection complicated by stroke: can immediate repair be performed safely? J Thorac Cardiovasc Surg. 2006;132(6):1404–8. PubMed PMID: 17140967.

    Article  PubMed  Google Scholar 

  26. Ergin MA, Phillips RA, Galla JD, Lansman SL, Mendelson DS, Quintana CS, et al. Significance of distal false lumen after type A dissection repair. Ann Thorac Surg. 1994;57(4):820–4. discussion 5. PubMed PMID: 8166525.

    Article  CAS  PubMed  Google Scholar 

  27. Kimura N, Tanaka M, Kawahito K, Yamaguchi A, Ino T, Adachi H. Influence of patent false lumen on long-term outcome after surgery for acute type A aortic dissection. J Thorac Cardiovasc Surg. 2008;136(5):1160–6, 6 e1–3. PubMed PMID: 19026797.

    Article  PubMed  Google Scholar 

  28. Fattori R, Bacchi-Reggiani L, Bertaccini P, Napoli G, Fusco F, Longo M, et al. Evolution of aortic dissection after surgical repair. Am J Cardiol. 2000;86(8):868–72. PubMed PMID: 11024403.

    Article  CAS  PubMed  Google Scholar 

  29. Lai DT, Miller DC, Mitchell RS, Oyer PE, Moore KA, Robbins RC, et al. Acute type A aortic dissection complicated by aortic regurgitation: composite valve graft versus separate valve graft versus conservative valve repair. J Thorac Cardiovasc Surg. 2003;126(6):1978–86. PubMed PMID: 14688716.

    Article  PubMed  Google Scholar 

  30. Kazui T, Yamashita K, Washiyama N, Terada H, Bashar AH, Suzuki T, et al. Impact of an aggressive surgical approach on surgical outcome in type A aortic dissection. Ann Thorac Surg. 2002;74(5):S1844–7; discussion S57–63. PubMed PMID: 12440678.

    Article  PubMed  Google Scholar 

  31. David TE, Armstrong S, Ivanov J, Barnard S. Surgery for acute type A aortic dissection. Ann Thorac Surg. 1999;67(6):1999–2001; discussion 14–9. PubMed PMID: 10391357.

    Article  CAS  PubMed  Google Scholar 

  32. Fattouch K, Sampognaro R, Navarra E, Caruso M, Pisano C, Coppola G, et al. Long-term results after repair of type a acute aortic dissection according to false lumen patency. Ann Thorac Surg. 2009;88(4):1244–50. PubMed PMID: 19766814.

    Article  PubMed  Google Scholar 

  33. Kobuch R, Hilker M, Rupprecht L, Hirt S, Keyser A, Puehler T, et al. Late reoperations after repaired acute type A aortic dissection. J Thorac Cardiovasc Surg. 2012;144(2):300–7. PubMed PMID: 22078710.

    Article  PubMed  Google Scholar 

  34. Geirsson A, Bavaria JE, Swarr D, Keane MG, Woo YJ, Szeto WY, et al. Fate of the residual distal and proximal aorta after acute type a dissection repair using a contemporary surgical reconstruction algorithm. Ann Thorac Surg. 2007;84(6):1955–64; discussion 1955–64. PubMed PMID: 18036916.

    Article  PubMed  Google Scholar 

  35. Subramanian S, Leontyev S, Borger MA, Trommer C, Misfeld M, Mohr FW. Valve-sparing root reconstruction does not compromise survival in acute type A aortic dissection. Ann Thorac Surg. 2012;94:1230–34. PubMed PMID: 22748644.

    Google Scholar 

  36. Kallenbach K, Pethig K, Schwarz M, Milz A, Haverich A, Harringer W. Valve sparing aortic root reconstruction versus composite replacement—perioperative course and early complications. Eur J Cardio Thorac Surg Off J Eur Assoc Cardio Thorac Surg. 2001;20(1):77–81. PubMed PMID: 11423278.

    Article  CAS  Google Scholar 

  37. Chamogeorgakis T, Angouras D, Toumpoulis I, Niki N, Lozos V, Xenikakis T, et al. Reoperativ repair of the aortic root and the aortic arch following previous surgery for acute type A dissection. Chirurgia. 2009;22(4):171–5.

    Google Scholar 

  38. Estrera AL, Miller 3rd CC, Villa MA, Lee TY, Meada R, Irani A, et al. Proximal reoperations after repaired acute type A aortic dissection. Ann Thorac Surg. 2007;83(5):1603–8; discussion 8–9. PubMed PMID: 17462365.

    Article  PubMed  Google Scholar 

  39. Concistre G, Casali G, Santaniello E, Montalto A, Fiorani B, Dell’Aquila A, et al. Reoperation after surgical correction of acute type A aortic dissection: risk factor analysis. Ann Thorac Surg. 2012;93(2):450–5. PubMed PMID: 22206955.

    Article  PubMed  Google Scholar 

  40. Tan ME, Dossche KM, Morshuis WJ, Kelder JC, Waanders FG, Schepens MA. Is extended arch replacement for acute type a aortic dissection an additional risk factor for mortality? Ann Thorac Surg. 2003;76(4):1209–14. PubMed PMID: 14530014.

    Article  PubMed  Google Scholar 

  41. Lansman SL, Raissi S, Ergin MA, Griepp RB. Urgent operation for acute transverse aortic arch dissection. J Thorac Cardiovasc Surg. 1989;97(3):334–41. PubMed PMID: 2918732.

    CAS  PubMed  Google Scholar 

  42. Heinemann M, Laas J, Jurmann M, Karck M, Borst HG. Surgery extended into the aortic arch in acute type A dissection. Indications, techniques, and results. Circulation. 1991;84(5 Suppl):III25–30.

    CAS  PubMed  Google Scholar 

  43. Bachet J, Teodori G, Goudot B, Diaz F, el Kerdany A, Dubois C, et al. Replacement of the transverse aortic arch during emergency operations for type A acute aortic dissection. Report of 26 cases. J Thorac Cardiovasc Surg. 1988;96(6):878–86. PubMed PMID: 3269219.

    CAS  PubMed  Google Scholar 

  44. Crawford ES, Kirklin JW, Naftel DC, Svensson LG, Coselli JS, Safi HJ. Surgery for acute dissection of ascending aorta. Should the arch be included? J Thorac Cardiovasc Surg. 1992;104(1):46–59. PubMed PMID: 1614214.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stephen R. Large MA, MS, FRCS, MRCP, MBA, PaE .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag London

About this chapter

Cite this chapter

Sastry, P., Large, S.R. (2014). Rationale for a Conservative Approach and Arguments Against Aggressive Surgical Approaches. In: Bonser, R., Pagano, D., Haverich, A., Mascaro, J. (eds) Controversies in Aortic Dissection and Aneurysmal Disease. Springer, London. https://doi.org/10.1007/978-1-4471-5622-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-5622-2_10

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5621-5

  • Online ISBN: 978-1-4471-5622-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics