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The Mutagenic Activity of the Structurally Related Compounds Benzidine (BZD) and 4,4″-Diaminoterphenyl (DAT) in the Salmonella/Mammalian-Microsome Assay

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Comparative Genetic Toxicology

Summary

The mutagenic activity of BZD and DAT was investigated using the frameshift tester Salmonella typhimurium TA1538, and S9 prepared from the livers of Aroclor-induced F344 rats or non-induced chickens.

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Notes

  • Ames, B.N., McCann, J. and Yamasaki E. (1975). Methods for detecting carcinogens and mutagens with the Salmonella/ mammalian-microsome test. Mutation Res. 31: 347–364

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  • Vogel, H.J. and Bonner, D.M. (1956). Acetylornithase of E. coli: partial purification and some properties. J. Biol. Chem. 218: 97–106

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© 1985 United Kingdom Environmental Mutagen Society

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Brooks, T.M., Gonzalez, L.P. (1985). The Mutagenic Activity of the Structurally Related Compounds Benzidine (BZD) and 4,4″-Diaminoterphenyl (DAT) in the Salmonella/Mammalian-Microsome Assay. In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_5

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