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Bacterial Mutagenicity Assays: Co-ordinators’ Report

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Comparative Genetic Toxicology

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Abstract

This is a summary and analysis of the results of Salmonella/ mammalian-microsome assays of benzidine (BZD), 4,4″-diaminoterphenyl (DAT), 4-dimethylaminoazobenzene (DAB) and 4-cyanodimethylaniline (CDA). These results were obtained from assays performed by sixteen laboratories which participated in the Second UKEMS Collaborative Genotoxicity Study during 1982–3.

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Notes

  • Ames, B.N., McCann, J. and Yamasaki, E. (1975). Methods for detecting carcinogens and mutagens with the Salmonella/ mammalian-microsome test. Mutation Res. 31: 347–363

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  • IARC (1982) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans, Vol.29. International Agency for Research on Cancer, Lyon. pp.149–183 Resolution: Global

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  • Venitt, S. (1982). UKEMS Collaborative Genotoxicity Trial. Bacterial mutation tests of 4-chloromethylbiphenyl, 4-hydroxy-methylbiphenyl and benzyl chloride. Analysis of data from 17 laboratories. Mutation Res. 100: 91–109

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Author information

Authors and Affiliations

  1. Institute of Cancer Research, Clifton Avenue, Sutton, Surrey, UK

    S. Venitt

  2. Life Science Research, Roma Toxicology Centre, Via Tito Speri, 14 00040, Pomezia, Rome, Italy

    R. Forster

Authors
  1. S. Venitt
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  2. R. Forster
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Editor information

Editors and Affiliations

  1. Department of Genetics, University College Swansea, UK

    J. M. Parry

  2. MRC Cell Mutation Unit, University of Sussex, UK

    C. F. Arlett

Copyright information

© 1985 United Kingdom Environmental Mutagen Society

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Venitt, S., Forster, R. (1985). Bacterial Mutagenicity Assays: Co-ordinators’ Report. In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_16

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