Abstract
As a part of the Second UKEMS Collaborative Study DAB and CDA (Sample B) were tested for the induction of revertants in S. typhimurium TA1538 in the presence of uninduced mouse and uninduced rat liver S9. For the purpose of comparison we also included our own induced rat liver S9, prepared according to the method of Ames et al. (1975) from Fischer 344 rats which had been treated with Aroclor 1254 at 500 mg/kg over a five day period.
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Ames, B.N., McCann, J. and Yamasaki, E. (1975). Methods for detecting carcinogens and mutagens with the Salmonella/ mammalian-microsome mutagenicity test. Mutation Res. 31: 347–364
Ashby, J., Styles, J.A. and Paton, D. (1980). Studies in vitro to discern the structural requirements for carcinogenicity in analogues of the carcinogen 4-dimethylaminoazobenzene (Butter Yellow). Carcinogenesis 1: 1–7
de Serres, F.J. and Shelby, M.D. (1979). Recommendations on data production and analysis using the Salmonella/microsome mutagenicity assay. Mutation Res. 64: 159–165
de Serres, F.J. and Ashby J. (1981). Evaluation of Short-term Tests for Carcinogens (Progress in Mutation Research Ser. Vol. 1) Elsevier/ North Holland
Lefevre, P.A. and Ashby, J. (1981). The effects of preincubation period and norharman on the mutagenic potency of 4-dimethylaminoazobenzene and 3′-methyl-4-dimethylaminoazobenzene in S. typhimurium. Carcinogenesis 2: 927–931
Purchase, I.F.H., Longstaff, E., Ashby, J., Styles, J.A., Anderson, D., Lefevre, P.A. and Westwood, F.R. (1978). An evaluation of six short-term tests for detecting organic chemical carcinogens. Br. J. Cancer. 37: 873–959
Yahagi, T., Degawa, M., Seino, Y., Matsushima, T., Nagao, M., Sugimura, T. and Hashimoto, Y. (1975). Mutagenicity of carcinogenic azo dyes and their derivatives. Cancer Lett. 1: 91–96
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© 1985 United Kingdom Environmental Mutagen Society
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Varley, R.B., Rae, J.D., Kirkland, D.J. (1985). A Comparison of the Effects of Uninduced Mouse, Uninduced Rat and Aroclor-induced Rat Liver S9 on Reversion in Salmonella by DAB and CDA. In: Parry, J.M., Arlett, C.F. (eds) Comparative Genetic Toxicology. Palgrave Macmillan, London. https://doi.org/10.1007/978-1-349-07901-8_13
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DOI: https://doi.org/10.1007/978-1-349-07901-8_13
Publisher Name: Palgrave Macmillan, London
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