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Treatment of B-Cell Lymphoma

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Sjögren’s Syndrome

Abstract

Sjögren’s syndrome (SS) displays the highest incidence of malignant lymphoproliferative disorders among all of the autoimmune diseases. This association was highlighted in studies performed at the National Institutes of Health in the 1970s [1, 2] and verified in a meta-analysis that estimated the risk of Non-Hodgkin’s lymphoma (NHL) among the classic autoimmune diseases [3]. This meta-analysis reported that the possibility of an overt malignant lymphoproliferation is higher among SS patients (random effects standardized incidence rate (SIR) of 18.9 [95% confidence interval 9.4, 37.9]).

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Voulgarelis, M., Moutsopoulos, H.M. (2011). Treatment of B-Cell Lymphoma. In: Ramos-Casals, M., Stone, J., Moutsopoulos, H. (eds) Sjögren’s Syndrome. Springer, London. https://doi.org/10.1007/978-0-85729-947-5_37

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  • DOI: https://doi.org/10.1007/978-0-85729-947-5_37

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