Pediatric Sinusitis

Abstract

A computerized PubMed search of MEDLINE 1966-January 2006 was performed. Articles mapping to the exploded medical subject heading or keyword “sinusitis” were cross-referenced with those mapping to the text words (all fields) “chronic”, “recurrent”, or “persistent”. The resulting articles were then cross-referenced with those mapping to the medical subject headings “antibacterial agents,” “clindamycin,” “fluoroquinolones,” “macrolides,” or “infant,”, “adolescent” or the text word “pediatric.” This search process yielded 208 articles. These articles were then reviewed to identify those that met the following inclusion criteria: 1) pediatric patient population between ages 0 and 18 years old with nonacute sinusitis, 2) prospective intervention with antibiotic versus placebo, 3) outcome measured in terms of patient history, examination findings and/or X-ray examination. Articles were excluded if they focused on adults or patients with cystic fibrosis and other systemic diseases. This method yielded four articles.