Abstract
A computerized PubMed search of MEDLINE 1966–May 2006 was performed. The terms “thyroid,” “papillary,” and “thyroidectomy” were exploded and the resulting articles were cross-referenced, yielding 2203 trials. An additional search was performed to identify those that mapped to the medical subject headings “thyroid neoplasms” and “thyroidectomy,” as well as the text word “papillary,” which yielded 1139 studies. These articles were then reviewed to identify those that met the following inclusion criteria: 1) patient population with “low risk papillary thyroid carcinoma,” 2) intervention with total thyroidectomy versus unilateral lobectomy, 3) outcome measured in terms of survival (cause specific, overall, or otherwise) and disease recurrence. Articles were excluded if they included mixed follicular and papillary groups or did not specifically analyze low-risk groups. Many related papers pooled papillary and follicular cancers together. Although these two cancers are similar, they are also separate entities with clearly different natural histories and patterns of spread.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Haigh PI, Urbach DR, Rotstein LE. Extent of thyroidectomy is not a major determinant of survival in low-or high-risk papillary thyroid cancer. Ann Surg Oncol 2005;12(1):81–89.
Hay ID, Grant CS, Bergstralh EJ, Thompson GB, van Heerden JA, Goellner JR. Unilateral total lobectomy: is it sufficient surgical treatment for patients with AMES low-risk papillary thyroid carcinoma? Surgery 1998;124(6):958–964.
Hay ID, Thompson GB, Grant CS, et al. Papillary thyroid carcinoma managed at the Mayo Clinic during six decades (1940–1999): temporal trends in initial therapy and long-term outcome in 2444 consecutively treated patients. World J Surg 2002;26(8):879–885.
References
Brierley J, Tsang R, Panzarella T, Bana N. Prognostic factor and the effect of treatment with radioactive iodine and external beam radiation on patients with differentiated thyroid cancer seen at a single institution over the 40 years. Clin Endocrinol 2005;63:418–427.
Chow SM, Law SCK, Mendenhall WM, et al. Papillary thyroid carcinoma: prognostic factors and the role of radio-iodine and external radiotherapy. Int J Radiat Oncol Biol Phys 2002;52:784–795.
Sanders LE, Cady B. Differentiated thyroid cancer: re-examination of risk groups and outcome of treatment. Arch Surg 1998;133:419–425.
Greene FL, Page DL, Fleming ID, et al. AJCC Cancer Staging Manual. 6th ed. New York: Springer; 2002.
Cady B, Rossi R. An expanded view of risk-group definition in differentiated thyroid carcinoma. Surgery 1988;104:947–953.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Slough, C., Randolph, G.W. (2008). Papillary Thyroid Carcinoma. In: Shin, J.J., et al. Evidence-Based Otolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-49979-6_33
Download citation
DOI: https://doi.org/10.1007/978-0-387-49979-6_33
Publisher Name: Springer, New York, NY
Print ISBN: 978-0-387-24447-1
Online ISBN: 978-0-387-49979-6
eBook Packages: MedicineMedicine (R0)