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Epitope Specificity of Polyclonal Rabbit Antisera Against Proteus Vulgaris O-Antigens

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Genes and Proteins Underlying Microbial Urinary Tract Virulence

Conclusions

Acidic components, which are characteristic for many Proteus O-specific polysaccharides play an important role in manifesting immunospecificity of three out of four P. vulgaris O-antigens investigated in this paper._It was found that the immunological role of acidic components was determined also by other factors, such as the configuration of the glycosidic linkage and the type of neighbouring sugars.

The acidic nature of polysaccharides,which are present on the surface of Proteus strains,is believed to contribute to the formation of stones in urinary tract7and to facilitate the migration of swarm cells from these bacteria8.

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References

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© 2002 Kluwer Academic Publishers

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Bartodziejska, B. et al. (2002). Epitope Specificity of Polyclonal Rabbit Antisera Against Proteus Vulgaris O-Antigens. In: Emoődy, L., Pál, T., Hacker, J., Blum-Oehler, G. (eds) Genes and Proteins Underlying Microbial Urinary Tract Virulence. Advances in Experimental Medicine and Biology, vol 485. Springer, Boston, MA. https://doi.org/10.1007/0-306-46840-9_32

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  • DOI: https://doi.org/10.1007/0-306-46840-9_32

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46455-3

  • Online ISBN: 978-0-306-46840-7

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