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DNA Nanotechnology: From Structure to Functionality

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Closed
In 1980s, Nadrian C. Seeman put forward the concept of utilizing nucleic acids as a type of biomaterial to construct self-assembled nanostructures. Up to date, DNA has far exceeded its original function as gene code, and numerous static and dynamic DNA/RNA nanostructures have been designed and assembled following the highly specific Watson–Crick base-pairing rule. With the fast development of new techniques and new facilities, the field of DNA nanotechnology has been experiencing a rapid expansion and enrichment, and there has been ever-increasing demand for translational applications of those precisely assembled nucleic acids nanostructures. This issue of Topics in Current Chemistry will feature a Forum on DNA Nanotechnology. It will highlight the state-of-the-art advancement in the field of DNA Nanotechnology, focusing on the assembly and translational applications of these self-assembled DNA nanostructures. It will contain 12 Reviews authored by several active research groups in DNA Nanotechnology, covering from molecular basics to practical applications, and will provide readers an overview of the status of DNA nanotechnology with well selected and representative examples.

Editors

  • Chunhai Fan Chunhai Fan  &

    Chunhai Fan

    Chunhai Fan is a K. C. Wong Chair Professor at Shanghai Jiao Tong University (SJTU). Before joining SJTU, he was a CAS Distinguished Professor at the Shanghai Institute of Applied Physics, Chinese Academy of Sciences. He published over 400 papers in peer-reviewed journals. He is a fellow of Royal Society of Chemistry (FRSC), an elected fellow of the International Society of Electrochemistry (ISE) and American Association for the Advancement of Science (AAAS). His research interests include DNA nanotechnology, biosensing and bioimaging.

  • Yonggang Ke Yonggang Ke

    Yonggang Ke

    Yonggang Ke is an assistant professor at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University. He received his Ph.D. degree in chemistry from Arizona State University in 2009. He then worked as a postdoctoral fellow in the Department of Cancer Biology at Harvard University from 2009 to 2014. Dr. Ke is one of the leading experts in DNA nanotechnology. His current research focuses on programmable self-assembly of complex nanostructures and dynamic nanomachines using DNA and other biomolecules, functional nanomaterial self-assembly, drug delivery, and single-molecule biophysics.

Articles (12 in this collection)