Collection

Future Prospects in Radiation Oncology from the Perspective of Innovative Radiation Biology

Submission status
Closed
Current radiation biology covers a competence in investigating basic effects of ionizing radiation. By this, growing interest in the complex molecular circuits in malignant cells and in cellular interactions of different cell types present in tumor tissue resulted the emergence of innovative research areas covering biological targeting, and exploring the impact of the tumor microenvironment and immune system to combat radiation resistance. Moreover, experimental radiation oncology in interdisciplinary collaborations with biophysics, molecular biology, biochemistry and immunology covers an essential element in translational (radiation) oncological research. In this collection/special issue, we aim to bring together original research and review articles addressing the current landscape of radiobiological research in Germany and Europe covering DNA repair/damage response, aspects of immune modulation, tumor-stroma interactions, molecular targeting, biomarkers of radiation exposure, and the impact of different radiation qualities. In the end, this collection should provide innovative prospects in molecular radiation oncology and serve as a platform to guide future clinical developments.

Editors

  • Udo Gaipl Udo Gaipl  &

    Udo Gaipl

    Udo Gaipl is Head of Translational Radiobiology and Professor at the Department of Radiation Oncology of the Universitätsklinikum Erlangen, Germany. His research focuses on radiation-induced stimulators and suppressor of the immune system, on osteoimmunological modes of action of low radiation doses, on combination of radio(chemo)therapy with immunotherapies including hyperthermia, and on immune biomarkers obtained from translational studies. He has published over 200 peer-reviewed papers on immune modulations by radiation, activated and stressed cells and is Section Editor for Radiation Biology of the journal Strahlentherapie und Onkologie

  • Franz Rödel Franz Rödel

    Franz Rödel

    Franz Rödel is Professor for Molecular Radiation Biology at the Department of Radiotherapy and Oncology at the University Hospital Frankfurt am Main, Germany. His research focuses on immunomodulatory effects of ionizing radiation, identification of biological/immunological markers to predict therapy response, translational research in rectal and anal cancer and on molecular-targeted therapies to overcome radiation resistance of malignant cells. Prof. Rödel has published 180 peer-reviewed papers on these topics and is Section Editor for Radiation Biology of the journal Strahlentherapie und Onkologie

Articles (13 in this collection)