Neglected tropical diseases (NTDs) present formidable global challenges, disproportionately affecting vulnerable populations who struggle with restricted access to healthcare, clean water, and sanitation. BMC Infectious Diseases invites submissions addressing various aspects of NTDs but not limited to: epidemiological studies, clinical research, socioeconomic analyses, public health and policy initiatives, research advancing the understanding of NTD biology and pathogenesis, as well as the utilization of AI in their management.