Collection
Special Issue in honor of Prof. Edmond J. LaVoie
- Submission status
- Closed
We are delighted to announce this special issue of Med. Chem. Res. honoring Prof. LaVoie, a respected teacher and a well-known and highly regarded medicinal chemist. The special issue will be guest edited by Dr. Matthew Moschitto and Dr. Alex Ruchelman. We would like to invite you to submit a review or research article to this special issue under the broad theme of drug design and discovery.
We aim for submission by May 1, 2022 and publication of the special issue in summer 2022.
Prof. LaVoie received his B.Sc. in Chemistry from Fordham University in Bronx, NY in 1971 and his Ph.D. in Medicinal Chemistry working with Prof. Wayne K. Anderson at the State University of New York at Buffalo in 1975 and conducted his post-doctoral study with Prof. S. Morris Kupchan in the Department of Chemistry at the University of Virginia, Charlottesville, VA from 1975 to 1976. He then joined the American Health Foundation and served as the Section Head of Metabolic Biochemistry and the Associate Chief of its Division of Environmental Carcinogenesis before he moved to Rutgers University in 1988 as a full professor of Medicinal Chemistry in the College of Pharmacy. He served as the Chairperson of the Department of Medicinal Chemistry between 1994 and 2017 and as the Director of the Graduate Program in Pharmaceutical Science between 1997 and 2000. He has received numerous awards including the NIH “MERIT AWARD” (1989-1999), Louis D. King Faculty Award for Outstanding Service to Undergraduate Pharmacy Students (1992, 1996), Teacher Appreciation Award (1994), Johnson and Johnson Research Discovery Fellowship (1994), William Levine Teacher of the Year (1995, 1996, 1997, 1999, 2000), Bartley J. Sciarrone Award for Compassion and Caring in Pharmacy-Rutgers College of Pharmacy from Rho Chi Honor Society (1997), New Jersey Department of Higher Education EOF Champion Award (2002), and Patent Award from Rutgers Office of Corporate Liaison and Technology Transfer for Outstanding Research (1997). He was elected as a Fellow of the National Academy of Inventors in 2019. He was a co-founder of TAXIS Pharmaceuticals, Inc. and served as a member of its Board of Directors between 2009 and 2019. He also co-founded Prodaptics Pharmaceuticals, Inc in 2011. He has published over 230 papers and has over 50 issued US patents.
Review articles or Research Articles are all welcome Please specify S.I.: Honoring Prof. LaVoie under Additional Information/Questionnaire tab during submissionEditors
-
Matthew Moschitto
Dr. Moschitto is an Assistant Professor of Medicinal Chemistry at the Ernest Mario School of Pharmacy, Rutgers University.
-
Alex Ruchelman
Dr. Ruchelman is an Associate Director at Bristol Myers Squibb.
Articles (14 in this collection)
-
-
Special issue of Medicinal Chemistry Research in honor of Professor Edmond J. LaVoie
Authors
- Alexander L. Ruchelman
- Longqin Hu
- Content type: Editorial
- Published: 06 September 2022
- Pages: 1621 - 1622
-
Combination with a FtsZ inhibitor potentiates the in vivo efficacy of oxacillin against methicillin-resistant Staphylococcus aureus
Authors (first, second and last of 6)
- Malvika Kaul
- Edgar Ferrer-González
- Daniel S. Pilch
- Content type: Original Research
- Published: 05 September 2022
- Pages: 1705 - 1715
-
A case history in natural product-based drug discovery: discovery of vorapaxar (Zontivity™)
Authors
- Samuel Chackalamannil
- Content type: Review Article
- Published: 02 September 2022
- Pages: 1623 - 1636
-
Discovery of mobocertinib, a new irreversible tyrosine kinase inhibitor indicated for the treatment of non-small-cell lung cancer harboring EGFR exon 20 insertion mutations
Authors (first, second and last of 4)
- Jun Wang
- Daniel Lam
- Longqin Hu
- Content type: Review Article
- Published: 01 September 2022
- Pages: 1647 - 1662
-
The history, mechanism, and perspectives of nirmatrelvir (PF-07321332): an orally bioavailable main protease inhibitor used in combination with ritonavir to reduce COVID-19-related hospitalizations
Authors
- Ryan P. Joyce
- Vivian W. Hu
- Jun Wang
- Content type: Review Article
- Published: 30 August 2022
- Pages: 1637 - 1646
-
Bio-guided isolation of anti-Alzheimer’s compounds from Phyllanthus niruri and role of niruriflavone in the reversal of aluminum chloride-induced neurobehavioral and biochemical changes in an animal model
Authors
- Gayathri Rajamanickam
- Manju SL
- Content type: Original Research
- Published: 24 August 2022
- Pages: 1740 - 1753
-
Discovery of α-methylene-γ-lactone-δ-epoxy derivatives with anti-cancer activity: synthesis, SAR study, and biological activity
Authors (first, second and last of 6)
- Jie Ren
- Pengchao Yu
- Kun Hu
- Content type: Original Research
- Published: 18 August 2022
- Pages: 1803 - 1817
-
Exploring thiazole-linked thioureas using alkaline phosphatase assay, biochemical evaluation, computational analysis and structure–activity relationship (SAR) studies
Authors (first, second and last of 14)
- Sajid Ali Channar
- Pervaiz Ali Channar
- Parvez Ali Mahesar
- Content type: Original Research
- Published: 13 August 2022
- Pages: 1792 - 1802
-
Design, synthesis and molecular docking studies of novel benzimidazole-1,3,4-oxadiazole hybrids for their carbonic anhydrase inhibitory and antioxidant effects
Authors (first, second and last of 8)
- Kaan Küçükoğlu
- Ulviye Acar Çevik
- Zafer Asım Kaplancıklı
- Content type: Original Research
- Published: 08 August 2022
- Pages: 1771 - 1782
-
Synthesis, characterization and biological evaluation of Bis-benzimidazolium salts and their silver(I)-N-heterocyclic carbene complexes
Authors (first, second and last of 5)
- Rana Yasir Nadeem
- Munazzah Yaqoob
- Muhammad Adnan Iqbal
- Content type: Original Research
- Published: 08 August 2022
- Pages: 1783 - 1791
-
Development of new donepezil analogs: synthesis, biological screening and in silico study rational
Authors (first, second and last of 4)
- Zeinab Mahmoud
- Hadeer S. Sayed
- Khaled O. Mohamed
- Content type: Original Paper
- Open Access
- Published: 04 August 2022
- Pages: 1754 - 1770
-
Design, synthesis, and structure–activity relationships of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as inhibitors of the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) immune checkpoint pathway
Authors
- Jeffrey Yang
- Subhadwip Basu
- Longqin Hu
- Content type: Original Research
- Published: 14 July 2022
- Pages: 1716 - 1739
-
Antimicrobial activity of quaternary ammonium salts: structure-activity relationship
Authors (first, second and last of 8)
- Mallikarjuna N. Nadagouda
- Pooja Vijayasarathy
- Changseok Han
- Content type: Review Paper
- Published: 02 July 2022
- Pages: 1663 - 1678