Cytotoxic Reviews

Articles (27 in this collection)

1. Anti-cancer drug combinations approved by US FDA from 2011 to 2021: main design features of clinical trials and role of pharmacokinetics

   Authors (first, second and last of 8)

   • Salvador Fudio
   • Alvaro Sellers
   • Rubin Lubomirov

   • Content type: Review Article
   • Published: 27 August 2022

   • Pages: 285 - 299

   

2. Anti-drug antibodies in the current management of cancer

   Authors (first, second and last of 10)

   • Miguel Borregón
   • Katherine Martínez
   • Víctor Moreno

   • Content type: Review Article
   • Published: 25 March 2022

   • Pages: 577 - 584

   

3. Cytotoxic mechanisms of doxorubicin at clinically relevant concentrations in breast cancer cells

   Authors

   • Rachel E. Nicoletto
   • Clyde M. Ofner III

   • Content type: Review Article
   • Published: 12 February 2022

   • Pages: 285 - 311

   

4. Incidence of interstitial pneumonitis in breast cancer patients treated with pegylated liposomal doxorubicin

   Authors (first, second and last of 4)

   • Liwei Meng
   • Liming Huang
   • Wei Zhang

   • Content type: Review Article
   • Published: 03 August 2019

   • Pages: 3 - 7

   

5. Interactions of lean soft-tissue and chemotherapy toxicities in patients receiving anti-cancer treatments

   Authors

   • Jessica J. Hopkins
   • Michael B. Sawyer

   • Content type: Review Article
   • Published: 06 June 2018

   • Pages: 1 - 29

   

6. Cellular pharmacology studies of anticancer agents: recommendations from the EORTC-PAMM group

   Authors (first, second and last of 8)

   • Paola Perego
   • Georg Hempel
   • On behalf of the EORTC PAMM Group

   • Content type: Review Article
   • Published: 28 December 2017

   • Pages: 427 - 441

   

7. Positioning of proteasome inhibitors in therapy of solid malignancies

   Authors

   • Margot S. F. Roeten
   • Jacqueline Cloos
   • Gerrit Jansen

   • Content type: Review Article
   • Open Access
   • Published: 28 November 2017

   • Pages: 227 - 243

   

8. The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer

   Authors

   • Larry H. Matherly
   • Zhanjun Hou
   • Aleem Gangjee

   • Content type: Review Article
   • Published: 10 November 2017

   • Pages: 1 - 15

   

9. The dawn of “immune-revolution” in children: early experiences with checkpoint inhibitors in childhood malignancies

   Authors (first, second and last of 5)

   • Maurizio Lucchesi
   • Iacopo Sardi
   • Claudio Favre

   • Content type: Review Article
   • Published: 24 October 2017

   • Pages: 1047 - 1053

10. The potential of multi-compound nanoparticles to bypass drug resistance in cancer

    Authors (first, second and last of 4)

    • C. G. Da Silva
    • Godefridus J. Peters
    • Luis J. Cruz

    • Content type: Review Article
    • Open Access
    • Published: 08 September 2017

    • Pages: 881 - 894

    

11. DNA topoisomerase-targeting chemotherapeutics: what’s new?

    Authors

    • Selma M. Cuya
    • Mary-Ann Bjornsti
    • Robert C.A.M. van Waardenburg

    • Content type: Review Article
    • Published: 20 May 2017

    • Pages: 1 - 14

    

12. Neurotoxicity after high-dose methotrexate (MTX) is adequately explained by insufficient folinic acid rescue

    Authors

    • Ian Joseph Cohen

    • Content type: Review Article
    • Published: 28 April 2017

    • Pages: 1057 - 1065

13. Asparaginase pharmacology: challenges still to be faced

    Authors

    • Claudia Lanvers-Kaminsky

    • Content type: Review Article
    • Published: 14 February 2017

    • Pages: 439 - 450

    

14. The effect of cyclophosphamide on the immune system: implications for clinical cancer therapy

    Authors

    • Martina Ahlmann
    • Georg Hempel

    • Content type: Review Article
    • Published: 19 September 2016

    • Pages: 661 - 671

    

15. Irinotecan- and 5-fluorouracil-induced intestinal mucositis: insights into pathogenesis and therapeutic perspectives

    Authors (first, second and last of 8)

    • Ronaldo A. Ribeiro
    • Carlos W. S. Wanderley
    • Roberto C. P. Lima-Júnior

    • Content type: Review Article
    • Published: 02 September 2016

    • Pages: 881 - 893

    

16. Therapeutic potential of taxanes in the treatment of metastatic pancreatic cancer

    Authors

    • Radmila Lemstrova
    • Bohuslav Melichar
    • Beatrice Mohelnikova-Duchonova

    • Content type: Review Article
    • Published: 01 June 2016

    • Pages: 1101 - 1111

    

17. Therapeutic drug monitoring of 5-fluorouracil

    Authors

    • James J. Lee
    • Jan H. Beumer
    • Edward Chu

    • Content type: Review Article
    • Published: 23 May 2016

    • Pages: 447 - 464

18. Identifying novel therapeutic agents using xenograft models of pediatric cancer

    Authors

    • Raushan T. Kurmasheva
    • Peter J. Houghton

    • Content type: Review Article
    • Published: 18 May 2016

    • Pages: 221 - 232

    

19. Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

    Authors (first, second and last of 4)

    • Joseph Ciccolini
    • Cindy Serdjebi
    • Elisa Giovannetti

    • Content type: Review Article
    • Open Access
    • Published: 23 March 2016

    • Pages: 1 - 12

    

20. Platinum-based drugs: past, present and future

    Authors

    • Shahana Dilruba
    • Ganna V. Kalayda

    • Content type: Review Article
    • Published: 17 February 2016

    • Pages: 1103 - 1124

    

21. Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs

    Authors

    • Roger M. Phillips

    • Content type: Review Article
    • Open Access
    • Published: 25 January 2016

    • Pages: 441 - 457

    

22. Cytotoxic drugs: past, present and future

    Authors

    • Herbie Newell
    • Edward Sausville

    • Content type: Introduction
    • Published: 24 December 2015

    • Pages: 1 - 1

23. Contemporary reviews on cancer treatment

    Authors

    • Godefridus J. Peters
    • Eric Raymond

    • Content type: Introduction
    • Published: 24 December 2015

    • Pages: 3 - 4

24. Unique features of trabectedin mechanism of action

    Authors

    • Annette K. Larsen
    • Carlos M. Galmarini
    • Maurizio D’Incalci

    • Content type: Review Article
    • Published: 14 December 2015

    • Pages: 663 - 671

    

25. The druggability of intracellular nucleotide-degrading enzymes

    Authors (first, second and last of 4)

    • Chiara Rampazzo
    • Maria Grazia Tozzi
    • Lars Petter Jordheim

    • Content type: Review Article
    • Published: 27 November 2015

    • Pages: 883 - 893

    

26. Treatment regimens of classical and newer taxanes

    Authors

    • Markus Joerger

    • Content type: Review Article
    • Published: 20 November 2015

    • Pages: 221 - 233

    

27. Oxaliplatin in the era of personalized medicine: from mechanistic studies to clinical efficacy

    Authors

    • Paola Perego
    • Jacques Robert

    • Content type: Review Article
    • Published: 20 November 2015

    • Pages: 5 - 18