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Part of the book series: Current Clinical Practice ((CCP))

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Abstract

Cardiovascular disease (CVD) is the leading cause of death in the United States for both men and women. Although the precise number of people with elevated lipids depends on the definition chosen, it is clear that hyperlipidemia is one of the most important modifiable risk factors for coronary heart disease in the United States (Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults, 2001).

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References

  1. ALLHAT Investigators. Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). JAMA 288:2998–3007, 2002.

    Article  Google Scholar 

  2. Austin MA, Hokanson JE, Edwards KL. Hypertriglyceridemia as a cardiovascular risk factor. Am J Cardiol 81:7B–12B, 1998.

    Article  PubMed  CAS  Google Scholar 

  3. Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 350:1495–1504, 2004.

    Article  PubMed  CAS  Google Scholar 

  4. Davidson MH, McGarry T, Bettis R, et al. Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia. J Am Coll Cardiol 40:2125–2134, 2002.

    Article  PubMed  CAS  Google Scholar 

  5. Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults. Executive Summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evalution, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 285:2486–2496, 2001.

    Article  Google Scholar 

  6. Fonarow GC, Gawlinski A, Moughrabi S, Tillisch JH. Improved treatment of coronary heart disease by implementation of a Cardiac Hospitalization Atherosclerosis Management Program (CHAMP). Am J Cardiol 87:819–822, 2001.

    Article  PubMed  CAS  Google Scholar 

  7. Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. J Am Coll Cardiol 44:720–732, 2004.

    Article  PubMed  Google Scholar 

  8. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 360:7–22, 2002.

    Article  Google Scholar 

  9. LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 352:1425–1435, 2005.

    Article  PubMed  CAS  Google Scholar 

  10. Ridker PM, Cannon CP, Morrow D, et al. C-reactive protein levels and outcomes after statin therapy. N Engl J Med 352:20–28, 2005.

    Article  PubMed  CAS  Google Scholar 

  11. Sever PS, Dahlof B, Poulter NR, et al. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 361:1149–1158, 2003.

    Article  PubMed  CAS  Google Scholar 

  12. Shepherd J, Blauw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial. Lancet 360:1623–1630, 2002.

    Article  PubMed  CAS  Google Scholar 

  13. Wilson PW, D’Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation 97:1837–1847, 1998.

    PubMed  CAS  Google Scholar 

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© 2006 Humana Press Inc., Totowa, NJ

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(2006). Hyperlipidemia. In: Cardiology in Family Practice. Current Clinical Practice. Humana Press. https://doi.org/10.1385/1-59745-042-1:105

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  • DOI: https://doi.org/10.1385/1-59745-042-1:105

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-509-5

  • Online ISBN: 978-1-59745-042-3

  • eBook Packages: MedicineMedicine (R0)

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