Abstract
Laboratory diagnostic tests for viral infections play an important role in the management of infections during pregnancy and in the newborn infant. There are three basic laboratory approaches to diagnosis of viral infection: (1) isolation and identification, (2) serology, and (3) direct detection. The choice of approach depends on the agent suspected, the specimen submitted, and the resources of the laboratory. Isolation is considered the “gold standard,” but not all viruses grow well or at all in currently available culture systems. Serology is the method of choice when the virus is no longer likely to be present or cannot be cultured. Direct detection provides clinically relevant information in a minimum amount of time. The approach can be both highly sensitive and specific.
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© 2006 Humana Press Inc., Totowa, NJ
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Schnurr, D. (2006). Diagnosis of Viral Infections by Viral Isolation and Identification or by Direct Detection. In: Hutto, C. (eds) Congenital and Perinatal Infections. Infectious Disease. Humana Press. https://doi.org/10.1385/1-59259-965-6:023
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DOI: https://doi.org/10.1385/1-59259-965-6:023
Publisher Name: Humana Press
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