Abstract
Congestive heart failure has emerged as a major health problem during the past four decades (Bourassa et al., 1993). In spite of our advances, the underlying heart disease is relentlessly progressive in almost all patients who develop symptoms of overt failure, and mortality continues to be unacceptably high—approx 40% in 5 yr (Bourassa et al., 1993). Heart transplantation appears to be the only prospect to improve long-term survival for many patients.
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Anker, S. D., Chua, T. P., Ponikowski, P., Harrington, D., Swan, J. W., Kox, W. J., Poole-Wilson, P. A., & Coats, J. S. (1997). Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. Circulation, 96, 526–534.
Arsenian, M. A. (1997). Carnitine and its derivatives in cardiovascular disease. Progress in Cardiovascular Disease, 40, 265–286.
Azari, J., Brumbaugh, P., Barbeau, A., & Huxtable, R. (1980). Taurine decreases lesion severity in the hearts of cardiomyopathic Syrian hamsters. Canadian Journal of Neurological Sciences, 7, 435–440.
Azuma, J., Sawamura, A., & Awata, N. (1992). Usefulness of taurine in chronic congestive heart failure and its prospective application. Japanese Circulation Journal, 56, 95–99.
Ball, A. M. M. M., & Sole, M.J. (1998). Oxidative stress and the pathogenesis of heart failure. Cardiology Clinics, 16, 665–675.
Bourassa, M. G., Gurne, O., Bangdiwala, S. I., Ghali, J. K., Young, J. B., Rousseau, M., Johnstone, D. E., & Yusuf, S., for the Studies of Left Ventricular Dysfunction (SOLVD) Investigators. (1993). Natural history and patterns of current practice in heart failure. Journal of the American College of Cardiology, 22(Suppl. A), 14A–19A.
Brady, J. A., Rock, C. L., & Horneffer, M. R. (1995). Thiamine status, diuretic medications and the management of congestive heart failure. Journal of the American Dietetic Association, 95, 541–544.
Broqvist, M., Arnqvist, H., Dahlstrom, U., Larsson, J., Nylander, E., & Permet, J. (1994). Nutritional assessment and muscle energy metabolism in severe chronic congestive heart failure: Effects of long-term dietary supplementation. European Heart Journal, 15, 1641–1650.
Carr, J. G., Stevenson, L. W., Walden, J. A., & Heber, D. (1989). Prevalence and hemodynamic correlates of malnutrition in severe congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. American Journal of Cardiology, 63, 709–713.
Clark, A. L., Sparrow, J. L., & Coates, A. J. S. (1995). Muscle fatigue and dyspnea in chronic heart failure: Two sides of the same coin? European Heart Journal, 16, 49–52.
Diaz-Velez, C. R., Garcia-Castineiras, S., Mendoza-Ramos, E., & Hernandez Lopez, E. (1996). Increased malondialdehyde in peripheral blood of patients with congestive heart failure. American Heart Journal, 131, 146–152.
Douglas, S., Darling, P.B., Barr, A., Kurian, R., Sole, M., & Keith, M. (2003). Prevalence of thiamin deficiency in hospitalized patients with congestive heart failure. Canadian Journal of Cardiology, 19(Suppl. A), 193A.
Engel, A. G. (1986). Carnitine deficiency syndromes and lipid storage myopathies. In A. G. Engel & B. Q. Banker (Eds.) Myology, basic and clinical. (pp. 1663–1696). Toronto: McGraw-Hill.
Folkers, K., Langsjoen, P., Willis, R., Richardson, P., Xia, L. J., Ye, C. Q., & Tamagama, H. (1990). Lovastatin decreases coenzyme Q levels in humans. Proceedings of the National Academy of Sciences USA, 87, 8931–8934.
Folkers, K., Vadhanavikit, S., & Mortensen, S. A. (1985). Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10. Proceedings of the National Academy of Sciences USA, 82, 4240–4244.
Freeman, L., & Roubenoff, R. (1994). The nutrition implications of cardiac cachexia. Nutrition Reviews, 52, 340–347.
Ganapathy, V., & Leibach, F. H. (1994). Expression and regulation of the taurine transporter in cultured cell lines of human origin. In R. Huxtable & D.V. Michalk (Eds.), Taurine in health and disease. Advances in experimental medical biology (Vol. 359, pp. 51–57). New York: Plenum.
Geranmaygan, A., Keith, M., Sole, M.J., Kurian, R., Robinson, A., Omran, A. S., & Jeejeebhoy, K. N. (1998). Increased oxidative stress in patients with congestive heart failure. Journal of the American College of Cardiology, 31, 1352–1356.
Gordon, A., Hultman, E., & Kaijser, L. (1995). Creatine supplementation in chronic heart failure increases skeletal muscle creatine phosphate and muscle performance. Cardiovascular Research, 30, 413–418.
Grimble, R. F., Jackson, A. A., Persaud, C., Wride, M. J., Delers, F., & Engler, R. (1992). Cysteine and glycine supplementation modulate the metabolic response to tumor necrosis factor alpha in rats fed a low protein diet. Journal of Nutrition, 122, 2066–2073.
Guarnieri, C., Muscari, C., Manfroni, S., Caldarera, I., Stefanelli, C., & Pretolani, E. (1987). The effect of treatment with coenzyme Q10 on the mitochondrial function and superoxide radical formation in cardiac muscle hypertrophied by mild aortic stenosis. Journal of Molecular and Cellular Cardiology, 19, 63–71.
Harper, C. G., Giles, M., & Finlay-Jones, R. (1986). Clinical signs in the Wernicke-Korsakoff complex: A retrospective analysis of 131 cases diagnosed at necropsy. Journal of Neurological Neurosurgical Psychiatry, 49, 341–345.
Hofman-Bang, C., Rehnqvist, N., Swedberg, K., Wiklund, I., & Astrom, H., for the Q10 Study Group. (1995). Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. Journal of Cardiac Failure, 1, 101–107.
Huxtable, R.J., Chubb, J., & Azari J. (1980). Physiological and experimental regulation of taurine content in the heart. Federation Proceedings, 39, 2685–2690.
Iliceto, S., Scrutinio, D., Bruzzi, P., D’Ambrosio, G., Boni, L., Di Biase, M., Biasco, G., Hugenholtz, P. G., & Rizzon, P. J. (1995). Effects of l-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: The l-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. Journal of the American College of Cardiology, 26, 380–387.
Jeejeebhoy, F., Keith, M., Freeman, M., Barr, A., McCall, M., Kurian, R., Mazer, D., & Errett, L. (2002). Nutritional supplementation with MyoVive repletes essential cardiac myocyte nutrients and reduces left ventricular size in patients with left ventricular dysfunction. American Heart Journal, 143, 1092–1100.
Katz, A. M. (1989). The myocardium in congestive heart failure. American Journal of Cardiology, 63, 12A–16A.
Keith, M. E., Ball, A., Jeejeebhoy, K. N., Kurian, R., Butany, J., Dawood, F., Wen, W. H., Madapallimattam, A., & Sole, M. J. (2001) Conditioned nutritional deficiencies in the cardiomyopathic hamster heart. Canadian Journal of Cardiology, 17, 449–458.
Keith, M. E., Jeejeebhoy, K. N., Langer, A., Kurian, R., Barr, A., O’Kelly, B., & Sole, M. J. (2001). A controlled clinical trial of vitamin E supplementation in patients with congestive heart failure. American Journal of Clinical Nutrition, 73, 219–224.
Lake, N. (1994). Alterations of ventricular contractility and myofibrillar loss in taurine deficient hearts In R. Huxtable & D.V. Michalk (Eds.), Taurine in health and disease. Advances in experimental medical biology (Vol. 359, pp. 335–342). New York: Plenum.
Langsjoen, P. H., Vadhanavikit, S., & Folkers, K. (1985). Response of patients in classes III and IV of cardiomyopathy to therapy in a blind and crossover trial with coenzyme Q10. Proceedings of the National Academy of Sciences USA, 82, 4240–4244.
Li, R. K., Sole, M. J., Mickle, D. A. G., Schimmer, J., & Goldstein, D. (1997). Vitamin E and oxidative stress in the heart of the cardiomyopathic Syrian hamster. Free Radicals in Biology and Medicine, 24, 252–258.
Littaru, G. P. (1995). Energy and defence: Facts and perspectives on coenzyme Q10 in biology and medicine. Rome: Casa Editrice Scientifica Internazionale.
Momomura, S., Serizawa, T., Ohtani, Y., Izuka, M., & Sugimoto, T. (1991). Coenzyme Q10 attenuates the progression of cardiomyopathy in hamsters. Japanese Heart Journal, 32, 101–110.
Nascimben, L., Ingwall, J. S., Pauletto, P., Freidrich, J., Gwathmey, J. K., Saks, V., Pessina, A. C., & Allen, P. D. (1996). Creatine kinase system in failing and nonfailing human myocardium. Circulation, 94, 1894–1901.
Neubauer, S., Horn, M., Cramer, M., Harre, K., Newell, J. B., Peters, W., Pabst, T., Ertl, G., Hahn, D., Ingwall, J. S., & Kochsiek, K. (1997). In patients with cardomyopathy the myocardial phosphocreatine/ATP ratio predicts mortality better than ejection fraction or NYHA class. Circulation, 96, 2190–2196.
Ogasawara, M., Nakamura, T., Koyama, I., Nemoto, M., & Yoshida, T. (1994). Reactivity of taurine with aldehydes and its physiological role. In R. Huxtable & D.V. Michalk (Eds.), Taurine in health and disease. Advances in experimental medical biology. (Vol. 359, pp. 71–78). New York: Plenum.
Oudit, G. Y., Trivieri, M. G., Khaper, N., Husain, T., Wilson, G. J., Liu, P., Sole, M. J., & Backx, P. H. (2004). Taurine supplementation reduces oxidative stress and improves cardiovascular function in an iron-overload murine model. Circulation, 109, 1877–1885.
Pepine, C.J. (1991). The therapeutic potential of carnitine in cardiovascular disorders. Clinical Therapeutics, 13, 2–18.
Pfitzenmeyer, P., Guilland, J. C., d’Athis, Ph., Petit-Marnier, C., & Gaudet, M. (1994). Thiamine status of elderly patients with cardiac failure including the effects of supplementation. International Journal of Vitamin and Nutrition Research, 64, 113–118.
Pion, P. D., Kittleson, M. D,, Rogers, Q.R., & Morris, J. G. (1987). Myocardial failure in cats associated with low plasma taurine: A reversible cardiomyopathy. Science, 237, 764–768.
Schaffer, S. W., Allo, S., Harada, H., Mozaffari, M. (1987). Potentation of myocardial ischemic injury by drug-induced taurine depletion. In R. J. Huxtable, F. Franconi, & A. Giotti (Eds.), The biology of taurine (pp. 15–158). New York: Plenum.
Schonekess, B. O., Allard, M. F., & Lopaschuk, G. D. (1995). Proprionyl l-carnitine improvement of hypertrophied heart function is accompanied by an increase in carbohydrate oxidation. Circulation Research, 77, 726–734.
Seligmann, H., Halkin, H., Rauchfleisch, S., Kaufman, N., Motro, M., Vered, Z., & Ezra, D. (1991). Thiamine deficiency in patients with congestive failure receiving long-term furosemide therapy: A pilot study. American Journal of Medicine, 91, 151–155.
Shimon, I., Almong, S., Vered, Z., Seligmann, H., Shefi, M., Peleg, E., Rosenthal, T., Motro, M., Halkin, H., & Ezra, D. (1995). Improved left ventricular function after thiamine supplementation in patients with congestive heart failure receiving long-term furosemide therapy. American Journal of Medicine, 98, 485–490.
Singh, N., Dhalla, A.K., & Singal, P.K. (1995). Oxidative stress and heart failure. Molecular and Cellular Biochemistry, 147, 77–81.
Soja, A. M., & Mortenson, S. A. (1997). Treatment of congestive heart failure with coenzyme Q10 illuminated by meta-analysis of clinical trials. Molecular Aspects of Medicine, 18 (Suppl.), S159–168.
Sole, M. J. (1995). Shifting the paradigm for the treatment of dilated cardiomyopathy. European Heart Journal, 16(Suppl. O), 176–179.
Sole, M. J., & Jeejeebhoy, K. N. (2002). Conditioned nutritional requirements: Therapeutic relevance to heart failure. Herz, 27, 174–179.
Sturman, J. A. (1993). Taurine in development. Physiological Reviews, 73, 119–147.
Takihara, K., Azuma, J., & Awata, N. (1986). Beneficial effect of taurine in rabbits with chronic congestive heart failure. American Heart Journal, 112, 1278–1284.
Villalba, J. M., Navarro, F., Cordoba, F., Serrano, A., Arroyo, A., Crane, F. L., & Navas, P. (1995). Coenzyme Q reductase from liver plasma membrane: Purification and role in trans-plasma-membrane electron transport. Proceedings of the National Academy of Sciences U S A, 92, 4887–4891.
Vogt, A. M., & Kubler, W. (1998). Heart failure: Is there an energy deficit contributing to contractile dysfunction? Basic Research in Cardiology, 93, 1–10.
Witte, K. K. A,, Clark, A. L., & Cleland, J. G. F. (2001). Chronic heart failure and micronutrients. Journal of the American College of Cardiology, 37, 1765–1774.
Wyss, M., & Walliman, T. (1994). 1–4 Creatine metabolism and the consequences of creatine depletion in muscle. Molecular and Cellular Biochemistry, 133/134, 51–66.
Zeisel, S.H. (2000). Is there a metabolic basis for dietary supplementation? American Journal of Clinical Nutrition, 72 (Suppl.), 507s–511s.
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Sole, M.J. (2006). Conditioned Nutritional Requirements of the Failing Heart. In: Yehuda, S., Mostofsky, D.I. (eds) Nutrients, Stress, and Medical Disorders. Nutrition and Health. Humana Press. https://doi.org/10.1385/1-59259-952-4:341
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DOI: https://doi.org/10.1385/1-59259-952-4:341
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