Abstract
Focal status epilepticus (FSE) is a condition in which there is an anatomically discrete, continuously discharging epileptic disturbance, lasting more than 1 h (1), that is associated with a definable neurologic behavior. If that discrete and sustained discharge occurs in the temporal lobe or limbic region of the brain, the condition is referred to as nonconvulsive complex partial status epilepticus (discussed in Chapter 10). If the discharge is ongoing in systems that subserve language function, an aphasia may result (see Chapter 11). This chapter will deal with the disorders and conditions associated with FSE arising from other regions of the brain. This condition can be associated with a wide variety of neurologic disorders and have a multitude of signs and symptoms. These signs and symptoms vary according to the function of the brain area engaged by the discharge and can be as simple as a repetitive movement, as seen in epilepsia partialis continua (EPC), or as subtle as an inability to write to command (see case example).
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References
Juul-Jensen P, Denny-Brown D. Epilepsia partialis continua. Arch Neurol 1966;15:563–578.
Thomas JE, Reagen TJ, Klass DW. Epilepsia partialis continua. A review of 32 cases. Arch Neurol 1977;34:266–275.
Bancaud J, Bonis A, Trottier S, Talairach J, Dulac O. L’épilepsie partielle continue: syndrome et maladie. Rev Neurol (Paris) 1982;138:803–814.
Cowan JMA, Rothwell JC, Wise RJS, Marsden CD. Electrophysiological and positron emission studies in a patient with cortical myoclonus, epilepsia partialis continua and motor epilepsy. J Neurol Neurosurg Psychiatry 1986;49:796–807.
Singh BM, Strobos RJ. Epilepsia partialis continua associated with nonketotic hyperglycemia: clinical and biochemical profile of 21 patients. Ann Neurol 1980;8:155–160.
Oguni H, Andermann F, Rasmussen TB. The natural history of the syndrome of chronic encephalitis and epilepsy. A study of the MNI series of forty-eight cases. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:7–36.
Singh BM, Gupta DR, Strobos RJ. Nonketotic hyperglycemia and epilepsia partialis continua. Arch Neurol 1973;29:187–190.
Shiozawa Z, Sasaki H, Ozaki Y, Nakaniski T, Huang YP. Epilepsia partialis continua following metrizamide cisternography. Ann Neurol 1981;10:400–401.
Wroe SJ, Ellershaw JE, Whittaker JA, Richens A. Focal motor status epilepticus following treatment with azlocillin and cefotaxime. Med Toxicol 1987;2:233–234.
Lance JW. Simple formed hallucinations confined to the area of a specific visual field defect. Brain 1976;99:719–734.
Iizuka T, Sakai F, Suzuki N, Hata T, Tsukahara S, Fukuda M, Takiyama Y. Neuronal hyperexcitability in stroke-like episodes of MELAS syndrome. Neurology 2002;59:816–824.
Taylor I, Scheffer IE, Berkovic SF. Occipital epilepsies: identification of specific and newly recognized syndromes. Brain 2003;126:753–769.
Kozhevnikov A, Ya. (trans. Asher D). A particular type of cortical epilepsy (Epilepsia corticalis sive partialis continua). In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:245–262.
Zemskaya AG, Yatsuk SL, Samoilov VI. Intractable or partial epilepsy of infectious or inflammatory etiology: recent surgical experience in the U.S.S.R. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:271–282.
Bartolomei F, Gavaret M, Dhiver C, Gastaut JA, Gambarelli D, Figarell-Branger D, Gastaut JL. Isloated, chronic, epilepsia partialis continua in an HIV-infected patient. Arch Neurol 1999;56:111–114.
Aguilar MJ, Rasmussen T. Role of encephalitis in pathogenesis of epilepsy. Arch Neurol 1960;2:663–676.
Rasmussen T. Further observations on the syndrome of chronic encephalitis and epilepsy. Appl Neurophysiol 1978;41:1–12.
Gray F, Serdaru M, Baron H, Daumas-Duport C, Loron P, Sauron B, Poirier J. Chronic localized encephalitis (Rasmussen’s) in an adult with epilepsia partialis continua. J Neurol Neurosurg Psychiatry 1987;50:747–751.
Rogers SW, Andrews PI, Gahring LC, McNamara J. Autoantibodies to glutamate receptor GluR3 in Rasmussen’s encephalitis. Science 1996;46:242–246.
Meada Y, Oguni H, Saitou Y, Mutoh A, Imai K, Osawa M, Fukuyama Y, Tomokatsu T, Yamane F, Kubo O, Ishii K, Ishiwata K. Rasmussen syndrome: multifocal spread of inflammation suggested from MRI and PET findings. Epilepsia 2003;44:1118–1121.
Verhagen WI, Renier WO, ter Laak H, Jasper HH, Gabreels FJ. Anomalies of the cerebral cortex in a case of epilepsia partialis continua. Epilepsia 1988;29:57–62.
Bansal SK, Sawney IMS, Chopra JS. Epilepsia partialis continua in Sjögren’s syndrome. Epilepsia 1987;28:262–263.
Belopitova L, Bozhinova V, Khadzhibekov V. A variant of the epilepsia partialis continua syndrome in a child with hypoplasia of the internal carotid artery. Zh Nevropatol Psikhiatr Im S S Korsakova 1991;91:97–101.
Chatrian GE, Shaw CM, Plum F. Focal periodic slow transients in epilepsia partialis continua. Clinical and pathological correlations in two cases. Electroencephalogr Clin Neurophysiol 1964;16:387–393.
Botez MI, Brossard L. Epilepsia partialis continua with well-delimited subcortical frontal tumor. Epilepsia 1974;15:39–43.
Shahar E, Kramer U, Nass D, Savitzki D. Epilepsia partialis continua associated with widespread gliomatosis cerebri. Pediatr Neurol 2002;27:392–396.
Wilson SAK, MacBride HJ. Epilepsy as a symptom of disseminated sclerosis. J Neurology Psychopath 1925;6:91–103.
Hess DC, Sethi KD. Epilepsia partialis continua in multiple sclerosis. Int J Neurosci 1990;50:109–111.
Ziegler DK, Van Speybroech NW, Seitz EF. Myoclonic epilepsia partialis continua and Friedreich’s ataxia. Arch Neurol 1974;31:308–311.
Andermann F, Lugaresi E, Dvorkin GS, Montagna P. Malignant migraine: the syndrome of prolonged migraine, epilepsia partialis continua, and repeated strokes; a clinically characteristic disorder probably due to mitochrondial encephalopathy. Funct Neurol 1986;1:481–486.
Sabharwal RK, Gupta M, Sharma D, Puri V. Juvenile diabetes manifesting as epilepsia partialis continua. J Assoc Physicians India 1989;37:603–604.
Omorokov LI (trans. by Asher D). Kozhevnikov’s epilepsy in Siberia. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:263–270.
Laxer KD. Temporal lobe epilepsy with inflammatory pathologic changes. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:135–140.
Villemure JG, Andermann F, Rasmussen TB. Hemispherectomy for the treatment of epilepsy due to chronic encephalitis. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:235–244.
Morrell F, Whisler WW, Smith MC. Multiple subpial transection in Rasmussen’s encephalitis. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:219–234.
Dubeau F, Sherwin AL. Pharmacologic principles in the management of chronic encephalitis. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:179–192.
Brandt L, Saveland H, Ljunggren B, Andersson KE. Control of epilepsia partialis continua with intravenous nimodipine. Report of two cases. J Neurosurg 1988;69:949–950.
Prince DA, Connors BW. Mechanisms of epileptogensis in cortical structures. Ann Neurol 1984;16(suppl):S59–64.
Wieser HG, Graf HP, Bernoulli C, Siegfried J. Quantitative analysis of intracerebral recordings in epilepsia partialis continua. Electroencephalogr Clin Neurophysiol 1978;44:14–22.
Kuroiwa Y, Tohgi H, Takahashi A, Kanaya H. Epilepsia partialis continua: active cortical spike discharges and high blood flow in the motor cortex and enhanced transcortical long loop reflex. J Neurol 1985;232:162–166.
Chauvel P, Liegeois-Chauvel C, Marquis P, Bancaud J. Distinction between the myoclonus-related potential and the epileptic spike in epilepsia partialis continua. Electroencephalogr Clin Neurophysiol 1986;64:304–307.
Hallett M, Chadwick D, Marsden CD. Cortical reflex myoclonus. Neurology 1979;29:309–318.
Watanabe K, Kuroiwa Y, Toyokura A. Epilepsia partialis continua. Epileptogenic focus in motor cortex and its participation in transcortical reflexes. Arch Neurol 1984;41:1040–1044.
Kristiansen K, Kaada BR, Henriksen GF. Epilepsia partialis continua. Epilepsia 1971;12:263–267.
Siegfried J, Bernoulli C. Stereo-electroencephalographic exploration and epilepsia partialis continua. Acta Neurochir (Wien) 1976;23(suppl):183–191.
So NK, Gloor P. Electroencephalographic and electrocorticographic findings in chronic encephalitis of the Rasmussen type. In: Andermann F, ed. Chronic Encephalitis and Epilepsy. Boston: Butterworth-Heinemann; 1991:37–46.
Lee SH, Goldberg HI. Hypervascular pattern associated with idiopathic focal status epilepticus. Neuroradiology 1977;125:159–163.
Ruggieri PM, Najm I, Bronen R, Campos M, Cendes F, Duncan JS, Weiser HG, Theodore WH. Neuroimaging of the cortical dysplasias. Neurology 2004;62(suppl 3)S27–29.
Katz A, Bose A, Lind SJ, Spencer SS. SPECT in patients with epilepsia partialis continua. Neurology 1990;40:1848–1850.
Tatum WO, Sperling MR, Jacobstein JG. Epileptic palatal myoclonus. Neurology 1991;41:1305–1306.
Schomer DL, Penna A, Matton B, Seeck M, Slossman D, Roth S, Bidaut L, Landis T. Ictal agraphia: a case report. Neurology 1998;50;542–545.
Roeltgen DP, Heilman KM. Lexical agraphia. Further support for a two-system hypotheses of linguistic agraphia. Brain 1984;107;811–827.
Alexander MP, Fischer RS, Friedman R. Lesion localization in apractic agraphia. Arch Neurol 1992;49:246–251.
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Schomer, D.L. (2005). Focal Status Epilepticus. In: Drislane, F.W. (eds) Status Epilepticus. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-945-1:143
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