Using Magnetic Resonance Imaging to Select and Manage Patients for Treatment

  • Peter D. Schellinger
  • Chelsea S. Kidwell
  • Steven Warach
Part of the Current Clinical Neurology book series (CCNEU)


Thrombolysis is the treatment of choice for eligible acute stroke within 3 h after symptom onset. However, in the United States, only 2–5% of acute stroke patients receive this therapy, and among those patients who are treated there remains a risk of developing a symptomatic intracerebral hemorrhage (ICH) (1, 2, 3). Moreover, no treatment beyond 3 h has been approved by regulatory agencies. Thus, there is an urgent need to optimize safety and efficacy of thrombolytic therapy in the early time window (<3 h from onset), and identify selection criteria for therapies that can be safely extended into later time windows. Multimodal neuroimaging techniques are now available in the clinical setting and may provide an opportunity to meet both these needs.


Magnetic Resonance Imaging Apparent Diffusion Coefficient Acute Stroke Acute Ischemic Stroke Perfusion Compute Tomography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press Inc., Totowa, NJ 2005

Authors and Affiliations

  • Peter D. Schellinger
    • 1
  • Chelsea S. Kidwell
    • 2
  • Steven Warach
    • 3
  1. 1.Department of NeurologyUniversity Hospital at HeidelbergGermany
  2. 2.Department of NeurologyGeorgetown UniversityWashington
  3. 3.National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesda

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