The Epidermal Growth Factor Receptor Pathway as a Selective Molecular-Targeted Treatment in Human Breast Cancer

  • Fortunato Ciardiello
  • Teresa Troiani
  • Giampaolo Tortora
Part of the Cancer Drug Discovery and Development book series (CDD&D)


The regulation of normal breast development is dependent on several hormones. Among these hormones, estrogens play an essential role in the control of normal mammary development and in the etiology and progression of breast cancer.

Key Words

Breast cancer EGF EGFR 


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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Fortunato Ciardiello
    • 1
  • Teresa Troiani
    • 2
  • Giampaolo Tortora
    • 2
  1. 1.Cattedra di Oncologia Medica, Dipartimento Medico-Chirurgico di Internistica Clinica e Sperimentale F Magrassi e A LanzaraSeconda Universita degli Studi di NapoliNaplesItaly
  2. 2.Division of Medical Oncology, Department of Molecular and Clinical Endocrinology and OncologyUniversita di Napoli Federico IINaplesItaly

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