Abstract
In this chapter various methods for tissue array construction are compared and protocols for constructing tissue arrays in multicenter trial setting are provided. Listing of all available arrays for breast cancer including commercial and public sources are provided in the appendix.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Kononen J, Bubendorf L, Kallioniemi A, et al. Tissue microarray for high-throughput molecular profiling of tumor specimens. Nat Med 1998;4:844–847.
Jensen TA. Tissue microarray: advanced techniques. J Histotechnol 2003;26:101–104.
Jensen TA, Hammond E. The tissue microarray—a technical guide for histologists. J Histotechnol 2001;24:283–287.
Simon R, Mirlacher M, Sauter G. Tissue microarrays. Bio Techniques 2004;36:98–105.
Battifora H. The Multitumor (Sausage) Tissue Block: novel method for immuno-histochemical antibody testing. Lab Invest 1986;55:244–248.
Battifora H, Mehta P. The checkerboard tissue block. An improved multitissue control block. Lab Invest 1990;63:722–724.
Lampkin SR, Allred DC. Preparation of paraffin blocks and sections containing multiple tissue samples using a skin biopsy punch. J Histotechnol 1990;13:121–123.
Camp RL, Charette LA, Rimm DL. Validation of tissue microarray technology in breast carcinoma. Lab Invest 2000;80:1943–1949.
Zhang D, Salto-Tellez M, Putti TC, et al. Reliability of tissue microarrays in detecting protein expression and gene amplification in breast cancer. Mod Pathol 2003;16:79–84.
Camp RL, Dolled-Filhart M, King BL, Rimm DL. Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcome. Cancer Res 2003;63:1445–1448.
Pollack JR, Sorlie T, Perou CM, et al. Microarray analysis reveals a major direct role of DN A copy number alteration in the transcriptional program of human breast tumors. Proc Natl Acad Sci USA 2002;99:12963–12968.
Hyman E, Kauraniemi P, Hautaniemi S, et al. Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res 2002;62:6240–6245.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Humana Press Inc.
About this chapter
Cite this chapter
Kim, C., Paik, S. (2006). Tissue Microarrays. In: Gasparini, G., Hayes, D.F. (eds) Biomarkers in Breast Cancer. Cancer Drug Discovery and Development. Humana Press. https://doi.org/10.1385/1-59259-915-X:031
Download citation
DOI: https://doi.org/10.1385/1-59259-915-X:031
Publisher Name: Humana Press
Print ISBN: 978-1-58829-227-8
Online ISBN: 978-1-59259-915-8
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)