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Cardiac Surgery and Diabetes Mellitus

  • Chapter
Diabetes and Cardiovascular Disease

Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Diabetes mellitus (DM) is an established risk factor for the development and progression of cardiovascular disease (CVD). The prevalence of coronary artery disease (CAD) has been estimated as high as 55% in the diabetic population. It has been shown that diabetes is a major independent risk factor for CVD after adjustment for risk factors such as age, hypertension, hypercholesterolemia, and tobacco abuse (1). Patients with diabetes appear to develop more severe CAD with a greater tendancy toward adverse events. The relative risk of myocardial infarction (MI) is 50% greater in diabetic men and 150% greater in diabetic women (2). Approximately 20% of patients who have undergone coronary artery bypass grafting (CABG) have DM (3). Thus, diabetic patients undergoing surgical coronary revascularization represent a large and complex patient population. In the past decade, advancements in both percutaneous coronary intervention (PCI), primarily the use of stents, and surgical techniques, such as off-pump CABG and the use of arterial grafts, have continued to improve methods of coronary revascularization. Although there is evidence to suggest these new techniques have improved outcomes in diabetic patients, the optimal treatment for multivessel CAD continues to evolve for the diabetic patient population, which despite improvements in revascularization still suffers from significantly worse outcomes when compared to the general population.

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Author information

Authors and Affiliations

  1. Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Department of Medicine and Surgery, Harvard Medical School, Boston, MA

    Tanveer A. Khan MD

  2. Division of Cardiothoracic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Pierre Voisine MD & Frank W. Sellke MD

Authors
  1. Tanveer A. Khan MD
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  2. Pierre Voisine MD
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  3. Frank W. Sellke MD
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Editor information

Editors and Affiliations

  1. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Michael T. Johnstone MD, CM, FRCP(C)  & Aristidis Veves MD, DSC  & 

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© 2005 Humana Press Inc., Totowa, NJ

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Khan, T.A., Voisine, P., Sellke, F.W. (2005). Cardiac Surgery and Diabetes Mellitus. In: Johnstone, M.T., Veves, A. (eds) Diabetes and Cardiovascular Disease. Contemporary Cardiology. Humana Press. https://doi.org/10.1385/1-59259-908-7:543

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  • DOI: https://doi.org/10.1385/1-59259-908-7:543

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-413-5

  • Online ISBN: 978-1-59259-908-0

  • eBook Packages: MedicineMedicine (R0)

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