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Bone Regeneration and Repair pp 57–65Cite as

Biology of Bone Grafts

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Abstract

The need for bone grafting to replace skeletal defects or augment bony reconstruction has become more prevalent recently because of enhanced capability to salvage major bone loss. There are many bone graft options available for the surgeon, including autografts or allografts, either of a cortical or cancellous structure, each of which has specific biological and mechanical properties. Some grafts are more dependent on the host bed for successful incorporation, such as freeze-dried allografts, while others, such as vascularized autografts, are capable of incorporating into the host bone under adverse physiological conditions. An understanding of the biological events and biomechanical aspects of autografts and allografts is important in understanding the processes that influence the incorporation of the bone graft into the host skeleton.

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Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Case Western Reserve University, Cleveland, OH

    Victor M. Goldberg MD & Sam Akhavan MD

Authors
  1. Victor M. Goldberg MD
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  2. Sam Akhavan MD
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Editor information

Editors and Affiliations

  1. Department of Orthopaedic Surgery David Geffen School of Medicine, University of California, Los Angeles, CA

    Jay R. Lieberman MD

  2. Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, CT

    Gary E. Friedlaender MD

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© 2005 Humana Press Inc., Totowa, NJ

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Goldberg, V.M., Akhavan, S. (2005). Biology of Bone Grafts. In: Lieberman, J.R., Friedlaender, G.E. (eds) Bone Regeneration and Repair. Humana Press. https://doi.org/10.1385/1-59259-863-3:057

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  • DOI: https://doi.org/10.1385/1-59259-863-3:057

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-847-9

  • Online ISBN: 978-1-59259-863-2

  • eBook Packages: MedicineMedicine (R0)

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