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Part of the book series: Current Clinical Neurology ((CCNEU))

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Abstract

Two types of sleep apnea have been identified: obstructive sleep apnea (OSA) and central sleep apnea (CSA). OSA occurs when the upper airway collapses; in OSA, there is no airflow, often despite great respiratory effort. In CSA, the transitory cessations of breathing are because of a drop in respiratory capacity—there is no airflow and no respiratory effort. Excessive daytime sleepiness is a consequence of both OSA and CSA. A comprehensive history, ideally obtained from both the patient and bed partner, is the essential first step in diagnosing sleep apnea, but the gold standard for assessing sleep apnea is the polysomnogram. Sleep apnea has not been extensively evaluated in the setting of Parkinson’s disease (PD), but recent studies have suggested that OSA may be more common in PD than in age- and sex-matched controls, and obesity may not be as important a risk factor for OSA in PD as it is in the general population.

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References

  1. Standards of Practice Committee of the American Sleep Disorders Association. Practice Parameters for the Indications for Polysomnography and Related Procedures. American Sleep Disorders Association Report, 1997.

    Google Scholar 

  2. Sleep-Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research, The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22: 667–689.

    Google Scholar 

  3. Bassiri A, Guilleminault C. Clinical features and evaluation of obstructive sleep apnea-hypopnea syndrome. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 869.

    Google Scholar 

  4. Dement WC, Miles LE, Carskaden MA. “White paper” on sleep and aging. J Am Geriatric Soc 1982;30:25–50.

    CAS  Google Scholar 

  5. White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 827

    Google Scholar 

  6. Hudgel DW, Martin RJ, Johnson B, Hill P. Mechanics of the respiratory system and breathing pattern during sleep in normal humans. J Appl Physiol 1984;56:133–137.

    PubMed  CAS  Google Scholar 

  7. Fouke JM, Teeter JP, Strohl KP. Pressure-volume behaviour of the upper airway. J Appl Physiol 1986; 61:912–918.

    PubMed  CAS  Google Scholar 

  8. Morikawa S, Safar P, DeCarlo J. Influence of the head-jaw position upon upper airway patency. Anesthesiology 1981;22:265–270.

    Google Scholar 

  9. Skatrud J, Dempsey J. Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilation. J Appl Physiol 1983;55:813–822.

    PubMed  CAS  Google Scholar 

  10. Xie A, Wong B, Phillipson EA, et al. Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apnea. Am J Respir Crit Care Med 1994;150:489–495.

    PubMed  CAS  Google Scholar 

  11. White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, pp. 830–831.

    Google Scholar 

  12. White DP. Ventilation and the control of respiration during sleep: normal mechanisms, pathologic nocturnal hypoventilation, and central sleep apnea. In: Martin R, ed. Cardiorespiratory Disorders During Sleep, 2nd ed. Futura, New York, 1990, p. 97.

    Google Scholar 

  13. Lockwood AH. Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release. Arch Neurol 1976;33:292–295.

    PubMed  CAS  Google Scholar 

  14. White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 833.

    Google Scholar 

  15. American Sleep Disorders Association. The International Classification of Sleep Disorders, Revised Diagnostic and Coding Manual. American Sleep Disorders Association, Rochester, MN, 1997, pp. 52–58.

    Google Scholar 

  16. White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 834.

    Google Scholar 

  17. ASDA practice parameters for the use of portable recordings in the assessment of obstructive sleep apnea. Sleep 1997;20:406–422.

    Google Scholar 

  18. Riley RW, Powell NB, Li KK, Guilleminault C. Obstructive sleep apnea syndrome: a surgical protocol for dynamic upper airway reconstruction. J Oral Maxillofacial Surg 1993;51:742–747.

    Article  CAS  Google Scholar 

  19. Sin DD, Mayers I, Man G, Pawluk L. Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based study. Chest 2002;121:430–435.

    Article  PubMed  Google Scholar 

  20. Sanders MH. The management of sleep-disordered breathing. In: Martin R, ed. Cardiorespiratory Disorders During Sleep, 2nd ed. Futura, New York, 1990, pp. 172–173.

    Google Scholar 

  21. Frucht S, Rogers JD, Greene PE, et al. Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole. Neurology 1999;52:1908–1910.

    PubMed  CAS  Google Scholar 

  22. Ondo WG, Dat Vuong K, Khan H, et al. Daytime sleepiness and other sleep disorders in Parkinson’s disease. Neurology 2001;57:1392–1396.

    PubMed  CAS  Google Scholar 

  23. Factor SA, McAlarney T, Sanchez-Ramos JR, Weiner WJ. Sleep disorders and sleep effect in Parkinson’s disease. Mov Disord 1990;5:280–285.

    Article  PubMed  CAS  Google Scholar 

  24. Tandberg E, Larsen JP, Karlsen. A community-based study of sleep disorders in patients with Parkinson’s disease. Mov Disord 1998;13:895–899.

    Article  PubMed  CAS  Google Scholar 

  25. Apps MCP, Sheaff PC, Ingram DA, et al. Respiration and sleep in Parkinson’s disease. J Neurol Neurosurg Psych 1985;48:1240–1245.

    Article  CAS  Google Scholar 

  26. Efthimiou J, Ellis SJ, Hardie RJ, Stern GM. Sleep apnea in idiopathic and postencephalitic Parkinsonism. Adv Neurol 1986;45:275–276.

    Google Scholar 

  27. Arnulf I, Konofal E, Merino-Andreu M, et al. Parkinson’s disease and sleepiness: an integral part of PD. Neurology 2002;58:1019–1024.

    PubMed  CAS  Google Scholar 

  28. Bixler EO, Vgontzas A, Ten Have T, Tyson, Kales A. Effects of age on sleep apnea in men. Am J Respir Crit Care Med 1998;157:144–148.

    PubMed  CAS  Google Scholar 

  29. Vincken WG, Gauthier SG, Dollfuss RE, et al. Involvement of upper-airway muscles in extrapyramidal disorders. A cause of airflow limitation. N Engl J Med 1984;311:438–442.

    Article  PubMed  CAS  Google Scholar 

  30. Hauser RA, Wahba MN, Zesiewicz TA, Anderson WM. Modafinil treatment of pramipexole-associated somnolence. Mov Disord 2000;15:1269–1271.

    Article  PubMed  CAS  Google Scholar 

  31. Adler CH, Caviness JN, Hentz JG, et al. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson’s disease. Mov Disord 2003;18:287–293.

    Article  PubMed  Google Scholar 

  32. Hauser RA, Zesiewicz TA, Delgado HM, et al. Evaluation and treatment of fatigue in Parkinson’s disease. Neurology 2002;58(Suppl 3):A433.

    Google Scholar 

  33. Silber MH, Levine S. Stridor and death in multiple system atrophy. Mov Disord 2000;15:699–704.

    Article  PubMed  CAS  Google Scholar 

  34. Chokroverty S, Sachdeo R, Masdeu J. Autonomic dysfunction and sleep apnea in olivopontocerebellar degeneration. Arch Neurol 1984;41:926–931.

    PubMed  CAS  Google Scholar 

  35. McNicholas WT, Rutherford R, Grossman R, et al. Abnormal respiratory pattern generation during sleep in patients with autonomic dysfunction. Am Rev Respir Dis 1983;128:429–433.

    PubMed  CAS  Google Scholar 

  36. Munschauer FE, Loh L, Bannister R, Newsome-Davis J. Abnormal respiration and sudden death during sleep in multiple system atrophy with autonomic failure. Neurology 1990;40:677–679.

    PubMed  CAS  Google Scholar 

  37. Kneisley LW, Rederich GJ. Nocturnal stridor in olivopontocerebellar atrophy. Sleep 1990;13: 362–368.

    PubMed  CAS  Google Scholar 

  38. Isozaki E, Hayashi M, Hayashida T, et al. Vocal cord abductor paralysis in multiple system atrophy—paradoxical movement of vocal cords during sleep. Rinsho Shinkeigaku 1996;36:529–533.

    PubMed  CAS  Google Scholar 

  39. Blumin JH, Vberke GS. Bilateral vocal cord paresis and multiple system atrophy. Arch Otolaryngol Head Neck Surg 2002;128:1404–1407.

    PubMed  Google Scholar 

  40. Merlo IM, Occhini, Paccheti C. Not paralysis, but dystonia causes stridor in multiple system atrophy. Neurology 2002;58:649.

    PubMed  Google Scholar 

  41. Iranzo A, Santamaria J, Tolosa E. Continuous positive air pressure eliminates nocturnal stridor in multiple system atrophy. Lancet 2000;356:1329–1330.

    Article  PubMed  CAS  Google Scholar 

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© 2005 Humana Press Inc., Totowa, NJ

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Carlucci, C.M., Hauser, R.A. (2005). Sleep Apnea. In: Pfeiffer, R.F., Bodis-Wollner, I. (eds) Parkinson’s Disease and Nonmotor Dysfunction. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-859-5:209

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  • DOI: https://doi.org/10.1385/1-59259-859-5:209

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-316-9

  • Online ISBN: 978-1-59259-859-5

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