Abstract
Two types of sleep apnea have been identified: obstructive sleep apnea (OSA) and central sleep apnea (CSA). OSA occurs when the upper airway collapses; in OSA, there is no airflow, often despite great respiratory effort. In CSA, the transitory cessations of breathing are because of a drop in respiratory capacity—there is no airflow and no respiratory effort. Excessive daytime sleepiness is a consequence of both OSA and CSA. A comprehensive history, ideally obtained from both the patient and bed partner, is the essential first step in diagnosing sleep apnea, but the gold standard for assessing sleep apnea is the polysomnogram. Sleep apnea has not been extensively evaluated in the setting of Parkinson’s disease (PD), but recent studies have suggested that OSA may be more common in PD than in age- and sex-matched controls, and obesity may not be as important a risk factor for OSA in PD as it is in the general population.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Standards of Practice Committee of the American Sleep Disorders Association. Practice Parameters for the Indications for Polysomnography and Related Procedures. American Sleep Disorders Association Report, 1997.
Sleep-Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research, The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22: 667–689.
Bassiri A, Guilleminault C. Clinical features and evaluation of obstructive sleep apnea-hypopnea syndrome. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 869.
Dement WC, Miles LE, Carskaden MA. “White paper” on sleep and aging. J Am Geriatric Soc 1982;30:25–50.
White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 827
Hudgel DW, Martin RJ, Johnson B, Hill P. Mechanics of the respiratory system and breathing pattern during sleep in normal humans. J Appl Physiol 1984;56:133–137.
Fouke JM, Teeter JP, Strohl KP. Pressure-volume behaviour of the upper airway. J Appl Physiol 1986; 61:912–918.
Morikawa S, Safar P, DeCarlo J. Influence of the head-jaw position upon upper airway patency. Anesthesiology 1981;22:265–270.
Skatrud J, Dempsey J. Interaction of sleep state and chemical stimuli in sustaining rhythmic ventilation. J Appl Physiol 1983;55:813–822.
Xie A, Wong B, Phillipson EA, et al. Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apnea. Am J Respir Crit Care Med 1994;150:489–495.
White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, pp. 830–831.
White DP. Ventilation and the control of respiration during sleep: normal mechanisms, pathologic nocturnal hypoventilation, and central sleep apnea. In: Martin R, ed. Cardiorespiratory Disorders During Sleep, 2nd ed. Futura, New York, 1990, p. 97.
Lockwood AH. Shy-Drager syndrome with abnormal respirations and antidiuretic hormone release. Arch Neurol 1976;33:292–295.
White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 833.
American Sleep Disorders Association. The International Classification of Sleep Disorders, Revised Diagnostic and Coding Manual. American Sleep Disorders Association, Rochester, MN, 1997, pp. 52–58.
White DP. Central sleep apnea. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd ed. W.B. Saunders, Philadelphia, PA, 2000, p. 834.
ASDA practice parameters for the use of portable recordings in the assessment of obstructive sleep apnea. Sleep 1997;20:406–422.
Riley RW, Powell NB, Li KK, Guilleminault C. Obstructive sleep apnea syndrome: a surgical protocol for dynamic upper airway reconstruction. J Oral Maxillofacial Surg 1993;51:742–747.
Sin DD, Mayers I, Man G, Pawluk L. Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based study. Chest 2002;121:430–435.
Sanders MH. The management of sleep-disordered breathing. In: Martin R, ed. Cardiorespiratory Disorders During Sleep, 2nd ed. Futura, New York, 1990, pp. 172–173.
Frucht S, Rogers JD, Greene PE, et al. Falling asleep at the wheel: motor vehicle mishaps in persons taking pramipexole and ropinirole. Neurology 1999;52:1908–1910.
Ondo WG, Dat Vuong K, Khan H, et al. Daytime sleepiness and other sleep disorders in Parkinson’s disease. Neurology 2001;57:1392–1396.
Factor SA, McAlarney T, Sanchez-Ramos JR, Weiner WJ. Sleep disorders and sleep effect in Parkinson’s disease. Mov Disord 1990;5:280–285.
Tandberg E, Larsen JP, Karlsen. A community-based study of sleep disorders in patients with Parkinson’s disease. Mov Disord 1998;13:895–899.
Apps MCP, Sheaff PC, Ingram DA, et al. Respiration and sleep in Parkinson’s disease. J Neurol Neurosurg Psych 1985;48:1240–1245.
Efthimiou J, Ellis SJ, Hardie RJ, Stern GM. Sleep apnea in idiopathic and postencephalitic Parkinsonism. Adv Neurol 1986;45:275–276.
Arnulf I, Konofal E, Merino-Andreu M, et al. Parkinson’s disease and sleepiness: an integral part of PD. Neurology 2002;58:1019–1024.
Bixler EO, Vgontzas A, Ten Have T, Tyson, Kales A. Effects of age on sleep apnea in men. Am J Respir Crit Care Med 1998;157:144–148.
Vincken WG, Gauthier SG, Dollfuss RE, et al. Involvement of upper-airway muscles in extrapyramidal disorders. A cause of airflow limitation. N Engl J Med 1984;311:438–442.
Hauser RA, Wahba MN, Zesiewicz TA, Anderson WM. Modafinil treatment of pramipexole-associated somnolence. Mov Disord 2000;15:1269–1271.
Adler CH, Caviness JN, Hentz JG, et al. Randomized trial of modafinil for treating subjective daytime sleepiness in patients with Parkinson’s disease. Mov Disord 2003;18:287–293.
Hauser RA, Zesiewicz TA, Delgado HM, et al. Evaluation and treatment of fatigue in Parkinson’s disease. Neurology 2002;58(Suppl 3):A433.
Silber MH, Levine S. Stridor and death in multiple system atrophy. Mov Disord 2000;15:699–704.
Chokroverty S, Sachdeo R, Masdeu J. Autonomic dysfunction and sleep apnea in olivopontocerebellar degeneration. Arch Neurol 1984;41:926–931.
McNicholas WT, Rutherford R, Grossman R, et al. Abnormal respiratory pattern generation during sleep in patients with autonomic dysfunction. Am Rev Respir Dis 1983;128:429–433.
Munschauer FE, Loh L, Bannister R, Newsome-Davis J. Abnormal respiration and sudden death during sleep in multiple system atrophy with autonomic failure. Neurology 1990;40:677–679.
Kneisley LW, Rederich GJ. Nocturnal stridor in olivopontocerebellar atrophy. Sleep 1990;13: 362–368.
Isozaki E, Hayashi M, Hayashida T, et al. Vocal cord abductor paralysis in multiple system atrophy—paradoxical movement of vocal cords during sleep. Rinsho Shinkeigaku 1996;36:529–533.
Blumin JH, Vberke GS. Bilateral vocal cord paresis and multiple system atrophy. Arch Otolaryngol Head Neck Surg 2002;128:1404–1407.
Merlo IM, Occhini, Paccheti C. Not paralysis, but dystonia causes stridor in multiple system atrophy. Neurology 2002;58:649.
Iranzo A, Santamaria J, Tolosa E. Continuous positive air pressure eliminates nocturnal stridor in multiple system atrophy. Lancet 2000;356:1329–1330.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Humana Press Inc., Totowa, NJ
About this chapter
Cite this chapter
Carlucci, C.M., Hauser, R.A. (2005). Sleep Apnea. In: Pfeiffer, R.F., Bodis-Wollner, I. (eds) Parkinson’s Disease and Nonmotor Dysfunction. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-859-5:209
Download citation
DOI: https://doi.org/10.1385/1-59259-859-5:209
Publisher Name: Humana Press
Print ISBN: 978-1-58829-316-9
Online ISBN: 978-1-59259-859-5
eBook Packages: MedicineMedicine (R0)