Brain Tumors pp 107-123 | Cite as

Analysis of Neural Precursor Cells in the Context of Origin of Brain Tumors, Their Treatment, and Repair of Treatment-Associated Damage

  • Mark Noble
  • Joerg Dietrich
Part of the Contemporary Cancer Research book series (CCR)


The treatment of any disease always begins with a correct diagnosis. It is here, before any treatment has been initiated, that enormous problems are faced by those involved in investigating brain tumors. Despite longstanding attempts to generate unambiguous diagnostic criteria for tumors of the central nervous system (CNS), the extent of disagreement between neuropathologists diagnosing the same tumor is often considerable (17,47,53,91). The importance of this disagreement cannot be understated. If pathologists are going to place identical tumors in different categories, then further analyses of outcomes as they pertain to diagnosis are severely compromised.


Stem Cell Brain Tumor Precursor Cell Neural Stem Cell Malignant Glioma 
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Copyright information

© Humana Press Inc., Totowa, NJ 2005

Authors and Affiliations

  • Mark Noble
    • 1
  • Joerg Dietrich
    • 1
  1. 1.Department of Biomedical GeneticsUniversity of Rochester Medical CenterRochester

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