Abstract
Poststroke dementia is a syndrome characterized by the acute onset of deficits in multiple cognitive domains, often including memory, after a clinical stroke, in a patient with nonrecognizable prestroke cognitive impairment. The interaction of various factors is necessary to produce its symptoms, and different clinical-pathologic correlates may lead to this diagnosis. At least two different mechanisms are responsible for poststroke dementia: strategic infarcts and mixed dementia resulting from the association with Alzheimer’s pathology.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Tatemichi TK, Desmond DW, Paik M, et al. Clinical determinants of dementia related to stroke. Ann Neurol 1993;33: 568–575.
Pohjasvaara T, Mantyla R, Salonen O, et al. MRI correlates of dementia after first clinical ischemic stroke. J Neurol Sci 2000;181:111–117.
Barba R, Martínez-Espinosa S, Rodrígues-García E, et al. Poststroke dementia. Clinical features and risk factors. Stroke 2000;31:1494–1501.
Pohjasvaara T, Erkinjuntti T, Ylikoski R, et al. Clinical determinants of poststroke dementia. Stroke 1998;29:75–81.
Desmond DW, Moroney JT, Paik MC, et al. Frequency and clinical determinants of dementia after ischemic stroke. Neurology 2000;54:1124–1131.
Censori B, Manara O, Agostini C, et al. Dementia after first stroke. Stroke 1996;27:1205–1210.
Hénon H, Pasquier F, Durieu I, et al. Preexisting dementia in stroke patients. Baseline frequency, associated factors and outcome. Stroke 1997;28:1932–1939.
Kokmen E, Whisnant JP, O’Fallon WM, et al. Dementia after ischemic stroke: a population-based study in Rochester, Minnesota (1960–1984). Neurology 1996;46:154–159.
Pasquier F, Didier L. Why are stroke patients prone to develop dementia. J Neurol 1997;244:135–142.
Auchus AP, Chen CPLH, Sodagar SN, et al. Single stroke dementia: insights from 12 cases in Singapore. J Neurol Sci 2002;203–204:85–89.
Tatemichi TK, Paik M, Beigelli MS, et al. Risk of dementia after stroke in a hospitalized cohort: results of a longitudinal study. Neurology 1994;44:1885–1891.
Tatemichi TK. How acute brain failure becomes chronic: a view of the mechanisms of dementia related to stroke. Neurology 1990;40:1652–1659.
Pohjasvaara T, Mäntylä R, Salonen O, et al. How complex interactions of ischemic brain infarcts, white matter lesions, and atrophy relate to poststroke dementia. Arch Neurol 2000;57:1295–1300.
Instar D, Di Carlo A, Paracusic G, et al. Incidence and determinants of poststroke dementia as defined by an informant interview method in a hospital-based stroke registry. Stroke 1998;29:2087–2093.
Cordoliani-Mackowiak MA, Hénon H, Pruvo JP, et al. Poststroke dementia—influence of hippocampal atrophy. Arch Neurol 2003;60:585–590.
Crisostomo RA, Garcia MM, Tong DC. Detection of diffusion-weighted MRI abnormalities in patients with transient ischemic attack: correlation with clinical characteristics. Stroke 2003;34:932–937.
Moroney JT, Bagiella E, Desmond DW, et al. Risk factors for incident dementia after stroke. Role of hypoxic and ischemic disorders. Stroke 1996;27:1283–1289.
Desmond DW, Tatemichi TK, Figueroa M, et al. Disorientation following stroke: frequency, course and clinical correlates. J Neurol 1994;241:585–591.
Knopman DS, Rocca WA, Cha RH, et al. Incidence of vascular dementia in Rochester, Minn, 1985–1989. Arch Neurol. 2002;59:1605–1610.
Laduner G, Iliff LD, Lechner H. Clinical factors associated with dementia in ischemic stroke. J Neurol Neurosurg Psychiatry 1982;45:97–101.
Román GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 1993;43:250–260.
McPherson SE, Cummings JL. Neuropsychological aspects of vascular dementia. Brain Cogn 1996;31:269–282.
Ferro J. Hyperacute cognitive stroke syndromes. J Neurol 2001;248:841–849.
Leys D, Erkinjuntti T, Desmond DW, et al. Vascular dementia: the role of cerebral infarcts. Alzheimer Dis Assoc Disord 1999;13(S3):S38–S48.
Cummings JL. Frontal-subcortical circuits and human behavior. Arch Neurol 1993;50:873–880.
Baron JC, D’Antona R, Pantano P, et al. Effects of thalamic stroke on energy metabolism of the cerebral cortex. A positron tomography study in man. Brain 1986;109:1243–1259.
Baron JC, Levasseur M, Mazoyer B, et al. Thalamocortical diaschisis: positron emission tomography in humans. J Neurol Neurosurg Psychiatry 1992;55:935–942.
Tatemichi TK, Desmond DW, Prohovnik I, et al. Confusion and memory loss from capsular genu infarction: a thalamocortical disconnection syndrome? Neurology 1992;42:1966–1979.
Tatemichi TK, Desmond DW, Prohovnik I. Strategic infarcts in vascular dementia. A clinical and brain imaging experience. Drug Research 1995;45:371–385.
Karnath HO, Himmelbach M, Rorden C. The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar. Brain 2002;125:350–360.
Caplan LR, Schmahmann JD, Kase CS, et al. Caudate infarcts. Arch Neurol 1990;47:133–143.
Mendez MF, Adams NL, Lewandowski KS. Neurobehavioral changes associated with caudate lesions. Neurology 1989;39:349–354.
Godefroy O, Rousseaux M, Leys D, et al. Frontal lobe dysfunction in unilateral lenticulostriate infarcts. Prominent role of cortical lesions. Arch Neurol 1992;49:1285–1289.
Kumral E, Evyapan D, Balkir K. Acute caudate vascular lesions. Stroke 1999;30:100–108.
Strub RL. Frontal lobe syndrome in a patient with bilateral globus pallidus lesions. Arch Neurol 1989;46:1024–1027.
Pantoni L, Basile AM, Romanelli M, et al. Abulia and cognitive impairment in two patients with capsular genu infarct. Acta Neurol Scand 2001;104:185–190.
Russmann H, Vingerhoets F, Ghika J, et al. Acute infarction limited to the lenticular nucleus. Clinical, etiologic and topographic features. Arch Neurol 2003;60:351–355.
Madureira S, Guerreiro M, Ferro JM. A follow-up study of cognitive impairment due to inferior capsular genu infarction. J Neurol 1999;246:764–769.
Stuss DT, Guberman A, Nelson R, Larochelle S. The neuropsychology of paramedian thalamic infarction. Brain Cogn 1988;8:348–378.
Bogousslavsky J, Regli F, Uske A. Thalamic infarcts: clinical syndromes, etiology, and prognosis. Neurology 1988;38:837–848.
Castaigne P, Lhermitte F, Buge A, Escourolle R, Hauw JJ, Lyon-Caen O. Paramedian thalamic and midbrain infarcts: clinical and neuropathological study. Ann Neurol 1981;10:127–148.
Graff-Radford NR, Tranel D, Van Hoesen GW, Brandt JP. Diencephalic amnesia. Brain 1990;113:1–25.
Bogousslavsky J, Regli F, Assal G. The syndrome of unilateral tuberothalamic artery territory infarction. Stroke 1986;17:434–441.
von Cramon DY, Hebel N, Schuri U. A contribution to the anatomical basis of thalamic amnesia. Brain 1985;108:993–1008.
Van Der Werf YD, Witter MP, Uylings HBM, Jolles J. Neuropsychology of infarctions in the thalamus: a review. Neuropsychologia 2000;38:613–627.
Van Der Werf YD, Scheltens P, Lindeboom J, et al. Deficits of memory, executive functioning and attention following infarction in the thalamus; a study of 22 cases with localized lesions. Neuropsychologia 2003;41:1330–1344.
Szirmai I, Vastagh I, Szombathelyi E, Kamondi A. Strategic infarcts of the thalamus in vascular dementia. J Neurol Sci 2002;203–204:91–97.
Neau JP, Bogousslavsky J. The syndrome of posterior choroidal artery territory infarction. Ann Neurol. 1996;39:779–788
Mayer E, Martory MD, Pegna AJ, et al. A pure case of Gerstmann syndrome with a subangular lesion. Brain 1999;122:1107–1120.
Ott BR, Saver JL. Unilateral amnesic stroke. Six new cases and review of the literature. Stroke 1993;24:1033–1042.
Rhoton AL, Fujii K, Fradd B. Microsurgical anatomy of the anterior choroidal artery. Surg Neurol 1979;12:171–187.
Hussein S, Renella RR, Dietz H. Microsurgical anatomy of the anterior choroidal artery. Acta Neurochir 1988;92:19–28.
von Cramon DY, Hebel N, Schuri U. Verbal memory and learning in unilateral posterior cerebral infarction. Brain 1988;111:1061–1077.
Pessin MS, Lathi ES, Cohen MB, Kwan ES, Hedges TR, Caplan LR. Clinical features and mechanism of occipital infarction. Ann Neurol 1987;21:290–299.
Damasio AR, Damasio H. The anatomic basis of pure alexia. Neurology 1983;33:1573–1583.
De Renzi E, Zambolin A, Crisi G. The pattern of neuropsychological impairment associated with left posterior cerebral artery infarcts. Brain 1987;110:1099–1116.
Servan J, Verstichel P, Catala M, et al. Aphasia and infarction of the posterior cerebral artery territory. J Neurol 1995;242:87–92.
Kumral E, Bayulkem G, Evyapan D, Yunten N. Spectrum of anterior cerebral artery territory infarction: clinical and MRI findings. Eur J Neurol. 2002;9:615–624.
Bogousslavsky J, Regli F. Anterior cerebral artery territory infarction in the Lausanne Stroke Registry. Arch Neurol 1990;47:144–150.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Humana Press Inc., Totowa, NJ
About this chapter
Cite this chapter
D′Abreu, A., Ott, B.R. (2005). Poststroke Dementia. In: Paul, R.H., Cohen, R., Ott, B.R., Salloway, S. (eds) Vascular Dementia. Current Clinical Neurology. Humana Press. https://doi.org/10.1385/1-59259-824-2:231
Download citation
DOI: https://doi.org/10.1385/1-59259-824-2:231
Publisher Name: Humana Press
Print ISBN: 978-1-58829-366-4
Online ISBN: 978-1-59259-824-3
eBook Packages: MedicineMedicine (R0)