Abstract
Patients with acute pancreatitis (AP) usually present with sudden onset of abdominal pain, nausea, and vomiting. Approximately 80% of patients have interstitial pancreatitis with mild-to-moderate symptoms, and 20% have life-threatening necrotizing disease. Careful clinical assessment and the judicial use of biochemical tests and radiological imaging enables the practitioner to differentiate AP from other causes of acute abdomen and to assess the severity of disease (1–7) .
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References
Topazian M, Gorelick F. Acute pancreatitis. In: Yamada T, ed. Textbook of Gastroenterology 3rd ed. Lippincott, Philadelphia, PA, 1999: 2121–2150.
Ranson JHC. Diagnostic standards for acute pancreatitis. World J Surg 1997; 21: 136–142.
Beger HG, Rau B, Mayer J, Pralle U. Natural course of acute pancreatitis. World J Surg 1997; 21: 130–135.
Mergener K, Baillie J. Acute pancreatitis. BMJ 1998; 316: 44–48.
Banks P. Acute and chronic pancreatitis. In: Feldman M, Scharschmidt B, Sleisenger M, eds. Sleisenger & Fordtran’s Gastrointestinal and Liver Disease 6th ed. Saunders, Philadelphia, PA, 1998: 809–862.
Levitt MD, Eckfeldt JH. Diagnosis of acute pancreatitis. In: Go V, Dimango E, Gardner J, et al., eds. The Pancreas: Biology, Pathophysiology and Disease 2nd ed. Raven Press, NY, 1993: 613–635.
Steinberg W, Tenner S. Acute pancreatitis. N Engl J Med 1994; 330: 1198–1210.
Banks PA. Practice guidelines in acute pancreatitis. Am J Gastroenterol 1997; 92: 377–386.
Triester SL, Kowdley KV. Prognostic factors in acute pancreatitis. J Clin Gastroenterol 2002; 34: 167–176.
Foitzik T, Bassi DG, Schmidt J, et al. Intravenous contrast medium accentuates the severity of acute necrotizing pancreatitis in the rat. Gastroenterology 1994; 106: 207–214.
Baron T, Morgan D. Acute necrotizing pancreatitis. N Engl J Med 1999; 340: 1412–1417.
Nuutinen P, Kivisaari L, Schroder T. Contrast-enhanced computed tomography and microangiography of the pancreas in acute human hemorrhagic/necrotizing pancreatitis. Pancreas 1988; 3: 53–60.
Baillie J. Treatment of acute biliary pancreatitis. N Engl J Med 1997; 336: 286–287.
Frakes J. Biliary pancreatitis: A review. J Clin Gastroenterol 1999; 28: 97–109.
Neoptolemos JP, Carr-Locke DL, Baily IA, et al. Controlled trial of urgent endoscopic retrograde cholangiopancreatography and endoscopic sphincterotomy versus conservative treatment for acute pancreatitis due to gallstones. Lancet 1988; 2: 979–983.
Prat F, Edery J, Meduri B, et al. Early EUS of the bile duct before endoscopic sphincterotomy for acute biliary pancreatitis. Gastrrointest Endosc 2001; 54: 724–729.
Ranson JHC. Etiological and Prognostic factors in human acute pancreatitis: A review. Am J Gastroenterol 1982; 77: 633–638.
Balthazar E, Ranson JHC, Naidich DP, et al. Acute pancreatitis: Prognostic value of CT. Radiology 1985; 156: 767–772.
Balthazar E, Robinson DL, Meigibow AJ, Ranson JHC. Acute pancreatitis: value of CT in establishing prognosis. Radiology 1990; 174: 331–336.
Balthazar E. Acute pancreatitis: Assessment of severity with clinical and CT evaluation. Radiology 2002; 223: 603–613.
Brown A, Orav J, Banks PA. Hemoconcentration is an early marker for organ failure and necrotizing pancreatitis. Pancreas 2000; 20: 367–372.
Lankisch PG, Mahlke R, Blum T, et al. Hemoconcentration: An early marker of severe and/or necrotizing pancreatitis? A critical appraisal. Am J Gastroenterol 2001; 96: 2081–2086.
Baron T. Predicting the severity of acute pancreatitis: Is it time to concentrate on hematocrit?. Am J Gastroenterol 2001; 96: 1960–1961.
Whitcomb DC, Pederso MRA, Oliva J, et al. An admission hematocrit of 40 or less predicts a low risk of pancreatic necrosis and may reduce the need for diagnostic CT scans. Gastroenterology 1999; 116: A1176.
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© 2005 Humana Press Inc., Totowa, NJ
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Burton, F.R. (2005). Diagnosis and Risk Stratification of Acute Pancreatitis. In: Forsmark, C.E. (eds) Pancreatitis and Its Complications. Clinical Gastroenterology. Humana Press. https://doi.org/10.1385/1-59259-815-3:017
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DOI: https://doi.org/10.1385/1-59259-815-3:017
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