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Use of Vasopressor Drugs in Cardiac Arrest

  • Chapter
Cardiopulmonary Resuscitation

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

The importance of vital organ perfusion in patients suffering cardiac arrest (CA) makes arterial vasomotor tone, and the resultant perfusion pressure, critical in resuscitation from sudden death. After failure of countershock, ventilation, and oxygenation, the target organ for resuscitative pharmacotherapy becomes the arterial vascular smooth muscle cell. Selective stimulation of various vascular smooth muscle cell surface receptors is accomplished through administration of exogenous agents with the intention of altering blood flow away from nonvital organ beds toward the myocardium and brain.

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Authors and Affiliations

  1. Department of Anesthesiology and Critical Care Medicine, Leopold-Franzens-University, Innsbruck, Austria

    Anette C. Krismer MD & Volker Wenzel MD

  2. Department of Emergency Medicine, University of Colorado Health Sciences Center, Denver, CO

    Norman A. Paradis MD

  3. Department of Surgery, University of Colorado Health Sciences Center, Denver, CO

    Norman A. Paradis MD

  4. Department of Medicine, University of Colorado Health Sciences Center, Denver, CO

    Norman A. Paradis MD

  5. Department of Emergency Medicine, Maine Medical Center, Portland, ME

    John Southall MD

Authors
  1. Anette C. Krismer MD
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  2. Norman A. Paradis MD
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  3. Volker Wenzel MD
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  4. John Southall MD
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Editor information

Editors and Affiliations

  1. Department of Emergency Medicine, Virginia Commonwealth University Health System, Richmond, VA

    Joseph P. Ornato MD, FACP, FACC, FACEP  & Mary Ann Peberdy MD, FACC  & 

  2. Department of Internal Medicine (Cardiology), Virginia Commonwealth University Health System, Richmond, VA

    Joseph P. Ornato MD, FACP, FACC, FACEP  & Mary Ann Peberdy MD, FACC  & 

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© 2005 Humana Press Inc., Totowa, NJ

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Krismer, A.C., Paradis, N.A., Wenzel, V., Southall, J. (2005). Use of Vasopressor Drugs in Cardiac Arrest. In: Ornato, J.P., Peberdy, M.A. (eds) Cardiopulmonary Resuscitation. Contemporary Cardiology. Humana Press. https://doi.org/10.1385/1-59259-814-5:305

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  • DOI: https://doi.org/10.1385/1-59259-814-5:305

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