Abstract
The first stage of lung development, which encompasses the first half of intrauterine life, consists of elaboration of a system of branching tubules derived from a bud arising from the endodermal tube, the branches being widely separated by the mesenchyme that proliferates simultaneously with the endodermal derivatives (Fig. 1; Table 1). The second stage begins at about midpregnancy and continues until after birth. It consists of vascularization of the tubular framework accompanied by progressive reduction in the intervening mesenchyme (Fig. 2).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Selected References
Atkins JP. Laryngeal problems of infancy and childhood. Pediatr Clin N Am 1962;9:1125.
Avery ME. The lung and its disorders in the newborn infant, 3rd ed. Philadelphia: WB Saunders, 1976.
Chen JC, Hollinger LD. Congenital tracheal anomalies: pathology study using serial macrosections and review of the literature. Pediatr Pathol 1994;14:513.
Chinwuba C, Wattman J, Strand R. Nasal airway obstruction: CT assessment. Radiology 1986;159:503.
Davis ME, Potter EL. Intrauterine respiration of the human fetus. JAMA 1946;131:1194.
Ey EH, Han PK, Towbin RP, et al. Bony inlet stenosis as a cause of nasal airway obstruction. Radiology 1988;168:477.
Fuzesi K, Young DG. Congenital laryngotracheoesophageal cleft. J Pediatr Surg 1976;11:933.
Gilbert EF, Opitz JM. Malformations and genetic disorders of the respiratory tract. In: Stocker JT, ed. Pediatric Pulmonary Disease, vol. 2. Washington, DC: Hemisphere, 1989.
Gilbert-Barness E. Respiratory system. In: Gilbert-Barness E, ed. Potter’s Pathology of the Fetus and Infant. Philadelphia: Mosby Year Book, Inc., 1997.
Holinger PH, Brown WT. Congenital webs, cysts, laryngoceles and other anomalies of the larynx. Ann Otol Rhinol Laryngol 1967;76:744.
Kavuru MS, Mehta AC, Eliachar I. Effect of photodynamic therapy and external beam radiation therapy on juvenile laryngotracheobronchial papillomatosis. Am Rev Respir Dis 1990;141:509.
Landing BH, Wells TR. Tracheobronchial anomalies in children. Perspect Pediatr Pathol 1975;1:132.
Langston C, Kida K, Reed M, et al. Human lung growth in late gestation and in the neonate. Am Rev Respir Dis 1984;129:607.
Langston C, Thurlbeck WM. Lung growth and development in late gestation and early postnatal life. Perspect Pediatr Pathol 1982;7:203.
Lubinsky M. Current concepts: VATER and other associations: historical perspectives and modern interpretations. Am J Med Genet 1986; 2(Suppl):9.
Parkin JL, Stevens MH, Jung AL. Acquired and congenital subglottic stenosis in the infant. Ann Otol Rhinol Laryngol 1976;85:573.
Stocker JT, Dehner LP. Pediatric Pathology, 2nd ed. Williams, Wilkins, Lippincott, Philadelphia, 2001.
Stocker JT. Respiratory system. In: Gilbert-Barness E, ed. Potter’s Atlas of Developmental and Infant Pathology. Philadelphia: Mosby Year Book, Inc., 1998.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Humana Press Inc., Totowa, NJ
About this chapter
Cite this chapter
(2005). Respiratory System. In: Gilbert-Barness, E., Debich-Spicer, D.E. (eds) Handbook of Pediatric Autopsy Pathology. Humana Press. https://doi.org/10.1385/1-59259-673-8:251
Download citation
DOI: https://doi.org/10.1385/1-59259-673-8:251
Publisher Name: Humana Press
Print ISBN: 978-1-58829-224-7
Online ISBN: 978-1-59259-673-7
eBook Packages: MedicineMedicine (R0)