Skip to main content

How to Practically Apply Lessons Learned from Translational Neuroscience to Intervention Development: Ideas for the Road Ahead

  • Chapter
Neuroimaging and Psychosocial Addiction Treatment

Abstract

One of the most frequent questions that we hear working in the area of translational neuroscience is, ‘The brain imaging work you are doing is compelling, but how will it inform treatment?’ Within other fields, many basic and clinical research teams have demonstrated that neuroimaging approaches are highly relevant to direct practice (e.g., informing the treatment of depression, obsessive-compulsive disorder, post-traumatic stress disorder) (Weingarten & Strauman, 2014). Despite these advances, few research groups have provided concrete information about what we can do with these data. This is indispensible because despite many real-world addiction treatment centers advertising the ability to alter neuronal connections or remedy brain deficits (e.g., brain restoration rapid detox, neurotransmitter restoration therapy), the connection between neuroscience and direct clinical practice is still nascent.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Feldstein Ewing, S. W., Filbey, F. M., Hendershot, C. S., McEachern, A. D., & Hutchison, K. E. (2011). ‘A proposed model of the neurobiolgocial mechanisms underlying psychosocial alcohol interventions: The example of motivational interviewing and functional magnetic resonance imaging’, Journal of Studies on Alcohol and Drugs, 72, 903–916.

    Article  Google Scholar 

  • Feldstein Ewing, S. W., Filbey, F. M., Sabbineni, A., & Hutchison, K. E. (2011). ‘How psychosocial alcohol interventions work: A preliminary look at what fMRI can tell us’, Alcoholism: Clinical and Experimental Research, 35(4), 1–9.

    Google Scholar 

  • Feldstein Ewing, S. W., McEachern, A. D., Yezhuvath, U., Bryan, A. D., Hutchison, K. E., & Filbey, F. M. (2013). ‘Integrating brain and behavior: Evaluating adolescents’ response to a cannabis intervention’, Psychology of Addictive Behaviors, 27, 510–525.

    Article  Google Scholar 

  • Feldstein Ewing, S. W., Yezhuvath, U., Houck, J. M., & Filbey, F. M. (2014). ‘Brain-based origins of change language: A beginning’, Addictive Behaviors, 39, 1904–1910.

    Article  Google Scholar 

  • Garrett, A. S., Miklowitz, D. J., Howe, M. E., Singh, M. K., Acquaye, T. K., Hawkey, C. G., Glover, G. H., Reiss, A. L., & Chang, K. D. (2015). ‘Changes in brain activation following psychotherapy for youth with mood dysregulation at familial risk for bipolar disorder’, Progress in Neuro-Psychopharmacology & Biological Psychiatry, 56, 215–220.

    Google Scholar 

  • Gaume, J., McCambridge J., Bertholet, N., & Daeppen, J. B. (2014). ‘Mechanisms of action of brief alcohol interventions remain largely unknown-a narrative review’, Frontiers in Psychiatry.

    Google Scholar 

  • Lisdahl, K. M., Gilbart, E. R., Wright, N. E., & Shollenbarger, S. (2013). ‘Dare to delay? The impacts of adolescent alcohol and marijuana use onset on cognition, brain structure, and function’, Front Psychiatry, 4, 53.

    Article  PubMed  PubMed Central  Google Scholar 

  • Miller, W. R., & Mount, K. A. (2001). ‘A small study of training in motivational interviewing: Does one workshop change clinician and client behavior?’ Behavioural and Cognitive Psychotherapy, 29(4), 457–471.

    Article  Google Scholar 

  • Miller, W. R., & Rollnick, S. (2013). Motivational Interviewing: Helping People Change, 3rd Edition. New York: Guilford Press.

    Google Scholar 

  • Prisciandaro, J. J., McRae-Clark, A. L., Myrick, H., Henderson, S., & Brady, K. A. (2012). ‘Brain activation to cocaine cues and motivation/treatment status’, Addiction Biology, 19, 240–249.

    Article  PubMed  PubMed Central  Google Scholar 

  • Robinson, M. J., & Berridge, K. C. (2013). ‘Instant transformation of learned repulsion into motivational “wanting”’. Curr Biol., 23, 282–289.

    Article  PubMed  PubMed Central  Google Scholar 

  • Volkow, N. D., & Baler, R. D. (2014). ‘Addiction science: Uncovering neurobiological complexity’, Neuropharmacology, 76, 235–249.

    Article  PubMed  Google Scholar 

  • Walsh, R. (2004). ‘What is good psychotherapy?’ Journal of Humanistic Psychology, 44, 455–467.

    Article  Google Scholar 

  • Weingarten, C. P., & Strauman, T. J. (2014). ‘Neuroimaging for psychotherapy reserach: Current trends’, Psychotherapy Research.

    Google Scholar 

  • Witkiewitz, K., Lustyk, M. K., & Bowen, S. (2013). ‘Retraining the addicted brain: a review of hypothesized neurobiological mechanisms of mindfulness-based relapse prevention’, Psychology of Addictive Behaviors, 27, 351–365.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Copyright information

© 2015 Sarah W. Feldstein Ewing, Katie Witkiewitz, and Francesca M. Filbey

About this chapter

Cite this chapter

Ewing, S.W.F., Witkiewitz, K., Filbey, F.M. (2015). How to Practically Apply Lessons Learned from Translational Neuroscience to Intervention Development: Ideas for the Road Ahead. In: Ewing, S.W.F., Witkiewitz, K., Filbey, F.M. (eds) Neuroimaging and Psychosocial Addiction Treatment. Palgrave Macmillan, London. https://doi.org/10.1057/9781137362650_17

Download citation

Publish with us

Policies and ethics