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Analysis of Androgens and Their Derivatives

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Steroid Analysis
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Abstract

In view of the enormous increase in the field of androgens during the past decade, an important decision had to be made concerning this present revised chapter. Some of the older material, prior to 1990, discussed in the first edition has been either omitted or, at least, summarised and presented in tabular form. This decision is not meant to detract from the importance of earlier studies. Interested readers can refer to earlier work in the first edition of ‘Steroid Analysis’ which is still available.

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Abbreviations

Testosterone:

17β-hydroxy-4-androstene-3-one

Epitestosterone:

17α-hydroxy-4-androsten-3-one

5α(β)-DHT:

17β-hydroxy-5α(β)-androstan-3-one

DHEA:

3β-hydroxy-5-androsten-17-one

4-Androstenedione:

4-androstene-3,17-dione

5α(β)-Androstanedione:

5α(β)-androstane-3,17-dione

Androsterone:

3α-hydroxy-5α-androstan-17-one

Aetiocholanolone:

3α-hydroxy-5β-androstan-17-one

Epiandrosterone:

3β-hydroxy-5α-androstan-17-one 5-androstenediol5-androstene-3α17β-diol

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Acknowledgements First, and most important, ‘Where does my help come from? My help has come, and still comes, from The LORD, maker of heaven and earth’ Psalm 121: 1–2 (slightly altered by DBG), The Bible.My sincere thanks also go to Dr. C.J. Baxter and Mrs. D.M. Gower for the many hours spent in searching the literature and typing the drafts of the present chapter, and to Mr. R. Dobb for help in general word-processing and in preparing the figures. Mr. A. Evans and Mr. R. Knight gave me invaluable advice in sorting out computer problems. I am most grateful to my friends and colleagues, Professor H.L.J. Makin, Drs. A.T. Kicman and M.J. Wheeler, who took the trouble to read parts of the manuscript, offering helpful criticism and pointing out references that I would otherwise have missed. Finally, I wish to acknowledge the kindness of many colleagues and publishers worldwide in giving permission for me to reproduce research results from various copyright journals and books. The literature survey for this chapter was completed in November 2008. D.B. Gower is Emeritus Professor of Steroid Biochemistry in the University of London and, formerly, Visiting Professor to the Drug Control Centre, King’s College London, 150, Stamford Street, London SE1 9NN.

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Correspondence to D. B. Gower .

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© 2010 Springer Science+Business Media B.V.

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Gower, D.B. (2010). Analysis of Androgens and Their Derivatives. In: Makin, H., Gower, D. (eds) Steroid Analysis. Springer, Dordrecht. https://doi.org/10.1023/b135931_6

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