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Regulation of exocytotic events by centrosome-analogous structures

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Book cover Regulatory Mechanisms of Intracellular Membrane Transport

Part of the book series: Topics in Current Genetics ((TCG,volume 10))

Abstract

Centrosomes, spindle pole bodies, and related structures, generally termed microtubule organising centres (MTOCs; Pickett-Heaps 1969), are best understood in the context of their function in the organisation of the mitotic spindle, spindle positioning via astral microtubule organisation, and regulation of cell cycle checkpoints (Doxsey 2001; Pereira and Schiebel 2001). However, cytological studies performed between 1960 and 1980 depict the involvement of MTOCs in membrane related events. These studies extend our definition of the processes that MTOCs regulate. In this review, we summarise some of this cytological knowledge in light of our current understanding of how centrosomes work. The focus of this review is on centrosome related membrane biogenesis processes, where a new membrane is formed from clearly distinct precursors. Central to this discussion is our current understanding of one example that takes place during yeast meiosis.

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Authors and Affiliations

  1. EMBL, Cell Biology and Biophysics Programme, Meyerhofstr. 1, 69117 Heidelberg,  

    Christof Taxis & Michael Knop

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  1. Christof Taxis
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  2. Michael Knop
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Correspondence to Christof Taxis .

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Sirkka Keränen Jussi Jäntti

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Taxis, C., Knop, M. Regulation of exocytotic events by centrosome-analogous structures. In: Keränen, S., Jäntti, J. (eds) Regulatory Mechanisms of Intracellular Membrane Transport. Topics in Current Genetics, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/b98734

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  • DOI: https://doi.org/10.1007/b98734

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-22302-3

  • Online ISBN: 978-3-540-44476-3

  • eBook Packages: Springer Book Archive

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